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67235437

Analogs

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-[3-(trifluoromethyl)phenyl]ace 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.51	11.25	-25.79	1	7	0	78	456.424	6	↓ MOL2 SDF SMILES Flexibase

67235443

Analogs

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Popular Name: N-(4-ethoxyphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(4-ethoxyphenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.07	10.46	-23.58	1	8	0	87	432.48	7	↓ MOL2 SDF SMILES Flexibase

67235462

Analogs

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Popular Name: N-(3-methoxyphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(3-methoxyphenyl)-2-[7-(3-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	9.54	-26.21	1	8	0	87	418.453	6	↓ MOL2 SDF SMILES Flexibase

67235466

Analogs

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Popular Name: N-(4-ethylphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(4-ethylphenyl)-2-[7-(3-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.55	11.67	-22.67	1	7	0	78	416.481	6	↓ MOL2 SDF SMILES Flexibase

67235468

Analogs

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Popular Name: N-(2-chlorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2-chlorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.27	10.87	-20.99	1	7	0	78	422.872	5	↓ MOL2 SDF SMILES Flexibase

67235471

Analogs

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Popular Name: N-(2,4-dimethoxyphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2,4-dimethoxyphenyl)-2-[7-(3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.68	8.93	-23.17	1	9	0	97	448.479	7	↓ MOL2 SDF SMILES Flexibase

67235473

Analogs

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acet N-(3-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	11.33	-21.9	1	7	0	78	436.899	5	↓ MOL2 SDF SMILES Flexibase

67235477

Analogs

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Popular Name: N-(2-methoxyphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2-methoxyphenyl)-2-[7-(3-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.65	9.65	-22.7	1	8	0	87	418.453	6	↓ MOL2 SDF SMILES Flexibase

67235480

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.19	11.82	-25.48	1	9	0	104	460.49	8	↓ MOL2 SDF SMILES Flexibase

67235482

Analogs

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Popular Name: N-ethyl-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-(m-tolyl)acetamide N-ethyl-2-[7-(3-methoxyphenyl)-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.69	13.42	-22.34	0	7	0	69	430.508	6	↓ MOL2 SDF SMILES Flexibase

67235496

Analogs

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Popular Name: N-(2-ethylphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2-ethylphenyl)-2-[7-(3-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.51	11.91	-22.8	1	7	0	78	416.481	6	↓ MOL2 SDF SMILES Flexibase

67235500

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.94	11.18	-20.8	1	9	0	104	446.463	7	↓ MOL2 SDF SMILES Flexibase

67235507

Analogs

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Popular Name: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin N-[2-chloro-5-(trifluoromethyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.14	11.86	-22.59	1	7	0	78	490.869	6	↓ MOL2 SDF SMILES Flexibase

67235509

Analogs

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Popular Name: N-(4-isopropylphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(4-isopropylphenyl)-2-[7-(3-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	12.16	-22.49	1	7	0	78	430.508	6	↓ MOL2 SDF SMILES Flexibase

67235511

Analogs

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Popular Name: N-(4-methoxyphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(4-methoxyphenyl)-2-[7-(3-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.70	9.53	-23.98	1	8	0	87	418.453	6	↓ MOL2 SDF SMILES Flexibase

67235514

Analogs

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Popular Name: N-(4-fluorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(4-fluorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.80	10.31	-23.59	1	7	0	78	406.417	5	↓ MOL2 SDF SMILES Flexibase

67235516

Analogs

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Popular Name: N-(3-chloro-4-methoxy-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]ace N-(3-chloro-4-methoxy-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.30	10.09	-26.61	1	8	0	87	452.898	6	↓ MOL2 SDF SMILES Flexibase

67235519

Analogs

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-(o-tolyl)acetamide 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.04	11.13	-23.47	1	7	0	78	402.454	5	↓ MOL2 SDF SMILES Flexibase

67235523

Analogs

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-(m-tolyl)acetamide 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.07	10.9	-22.71	1	7	0	78	402.454	5	↓ MOL2 SDF SMILES Flexibase

67235525

Analogs

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Popular Name: N-(4-bromo-2-fluoro-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]aceta N-(4-bromo-2-fluoro-phenyl)-2-[7…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.54	10.97	-20.57	1	7	0	78	485.313	5	↓ MOL2 SDF SMILES Flexibase

67235528

Analogs

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Popular Name: N-(3-chlorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(3-chlorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.29	10.76	-24.42	1	7	0	78	422.872	5	↓ MOL2 SDF SMILES Flexibase

67235531

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	12.16	-22.1	1	9	0	104	460.49	8	↓ MOL2 SDF SMILES Flexibase

67235535

Analogs

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-(2,4,6-trimethylphenyl)acetami 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.91	12.52	-22.45	1	7	0	78	430.508	5	↓ MOL2 SDF SMILES Flexibase

67235538

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acet N-(5-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	11.65	-25.03	1	7	0	78	436.899	5	↓ MOL2 SDF SMILES Flexibase

67235542

Analogs

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Popular Name: N-(2-chloro-4-methyl-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acet N-(2-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	11.52	-20.53	1	7	0	78	436.899	5	↓ MOL2 SDF SMILES Flexibase

67235543

Analogs

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Popular Name: N-(2,6-dimethylphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2,6-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	12.09	-22.98	1	7	0	78	416.481	5	↓ MOL2 SDF SMILES Flexibase

67235546

Analogs

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Popular Name: N-(2,4-difluorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2,4-difluorophenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.90	10.41	-20.9	1	7	0	78	424.407	5	↓ MOL2 SDF SMILES Flexibase

67235548

Analogs

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Popular Name: N-(2-fluorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2-fluorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	10.34	-21.73	1	7	0	78	406.417	5	↓ MOL2 SDF SMILES Flexibase

67235551

Analogs

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-methyl-N-phenyl-acetamide 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.89	11.93	-23.43	0	7	0	69	402.454	5	↓ MOL2 SDF SMILES Flexibase

67235554

Analogs

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Popular Name: N-(4-chloro-2-fluoro-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acet N-(4-chloro-2-fluoro-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.41	10.86	-20.6	1	7	0	78	440.862	5	↓ MOL2 SDF SMILES Flexibase

67235557

Analogs

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Popular Name: N-(4-bromophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(4-bromophenyl)-2-[7-(3-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.45	10.86	-22.93	1	7	0	78	467.323	5	↓ MOL2 SDF SMILES Flexibase

67235559

Analogs

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-phenyl-acetamide 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.64	10.24	-23.03	1	7	0	78	388.427	5	↓ MOL2 SDF SMILES Flexibase

67235561

Analogs

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Popular Name: N-(3,5-dimethoxyphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(3,5-dimethoxyphenyl)-2-[7-(3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.68	8.85	-26.08	1	9	0	97	448.479	7	↓ MOL2 SDF SMILES Flexibase

67235564

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Popular Name: N-(2-ethyl-6-methyl-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]aceta N-(2-ethyl-6-methyl-phenyl)-2-[7…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.97	12.73	-22.51	1	7	0	78	430.508	6	↓ MOL2 SDF SMILES Flexibase

67235567

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Popular Name: N-(4-chlorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(4-chlorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	10.76	-22.96	1	7	0	78	422.872	5	↓ MOL2 SDF SMILES Flexibase

67235569

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Popular Name: N-(2,5-dimethylphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2,5-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.47	11.75	-22.78	1	7	0	78	416.481	5	↓ MOL2 SDF SMILES Flexibase

67235572

Analogs

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Popular Name: N-(3,4-dimethoxyphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(3,4-dimethoxyphenyl)-2-[7-(3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.29	9.44	-26.12	1	9	0	97	448.479	7	↓ MOL2 SDF SMILES Flexibase

67235590

Analogs

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Popular Name: N-(3-bromophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(3-bromophenyl)-2-[7-(3-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.43	10.86	-24.37	1	7	0	78	467.323	5	↓ MOL2 SDF SMILES Flexibase

67235592

Analogs

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Popular Name: N-(2,5-difluorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2,5-difluorophenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.90	10.41	-22.6	1	7	0	78	424.407	5	↓ MOL2 SDF SMILES Flexibase

67235595

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Popular Name: N-(3-acetylphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(3-acetylphenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.52	10.64	-31.05	1	8	0	95	430.464	6	↓ MOL2 SDF SMILES Flexibase

67235628

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Popular Name: N-(3-fluorophenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(3-fluorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.78	10.31	-25.63	1	7	0	78	406.417	5	↓ MOL2 SDF SMILES Flexibase

67235637

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Popular Name: N-(2,3-dimethylphenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]acetamide N-(2,3-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.44	11.65	-22.88	1	7	0	78	416.481	5	↓ MOL2 SDF SMILES Flexibase

67235639

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-methyl-N-(m-tolyl)acetamide 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.31	12.59	-23.71	0	7	0	69	416.481	5	↓ MOL2 SDF SMILES Flexibase

67235656

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Popular Name: N-(2-methoxy-5-methyl-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]ace N-(2-methoxy-5-methyl-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.07	10.34	-22.43	1	8	0	87	432.48	6	↓ MOL2 SDF SMILES Flexibase

67235659

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-(3,4,5-trimethoxyphenyl)acetam 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.27	9.38	-27.4	1	10	0	106	478.505	8	↓ MOL2 SDF SMILES Flexibase

67235665

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Popular Name: 2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]ace 2-[7-(3-methoxyphenyl)-5-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.54	11.24	-23.62	1	7	0	78	456.424	6	↓ MOL2 SDF SMILES Flexibase

67235667

Analogs

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Popular Name: N-(5-chloro-2-methoxy-phenyl)-2-[7-(3-methoxyphenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]ace N-(5-chloro-2-methoxy-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.30	10.17	-23.33	1	8	0	87	452.898	6	↓ MOL2 SDF SMILES Flexibase

67235671

Analogs

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Popular Name: 2-[7-(4-chlorophenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-[3-(trifluoromethyl)phenyl]acet 2-[7-(4-chlorophenyl)-5-methyl-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.16	12.47	-23.9	1	6	0	69	460.843	5	↓ MOL2 SDF SMILES Flexibase

67235687

Analogs

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Popular Name: 2-[7-(4-chlorophenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-(3-methoxyphenyl)acetamide 2-[7-(4-chlorophenyl)-5-methyl-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	10.76	-24.37	1	7	0	78	422.872	5	↓ MOL2 SDF SMILES Flexibase

67235690

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Popular Name: 2-[7-(4-chlorophenyl)-5-methyl-4-oxo-pyrrolo[3,2-d]pyrimidin-3-yl]-N-(4-ethylphenyl)acetamide 2-[7-(4-chlorophenyl)-5-methyl-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.20	12.89	-20.87	1	6	0	69	420.9	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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SQL Query Was

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