UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: N-[(3,6-dimethylimidazo[2,1-b]thiazol-5-yl)methyl]-2-(4-methyl-1-piperidyl)ethanamine N-[(3,6-dimethylimidazo[2,1-b]th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 8.26 -44.91 2 4 1 34 307.487 5 ↓

Analogs

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Popular Name: N-[(6-methoxyimidazo[2,1-b]thiazol-5-yl)methyl]-2-(4-methyl-1-piperidyl)ethanamine N-[(6-methoxyimidazo[2,1-b]thiaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 5.53 -41.52 2 5 1 43 309.459 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2,6-dimethylimidazo[2,1-b]thiazol-5-yl)methyl]-2-(4-methyl-1-piperidyl)ethanamine N-[(2,6-dimethylimidazo[2,1-b]th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 8.72 -43.91 2 4 1 34 307.487 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(6-methylimidazo[2,1-b]thiazol-5-yl)methyl]-2-(4-methyl-1-piperidyl)ethanamine N-[(6-methylimidazo[2,1-b]thiazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 7.92 -44.42 2 4 1 34 293.46 5 ↓

Analogs

37782505
37782505
37782506
37782506
44686240
44686240
44686242
44686242
45692550
45692550

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Popular Name: (2S)-N-[(3,6-dimethylimidazo[2,1-b]thiazol-5-yl)methyl]-1-(1-piperidyl)propan-2-amine (2S)-N-[(3,6-dimethylimidazo[2,1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 8.8 -40.3 2 4 1 34 307.487 5 ↓

Analogs

37782505
37782505
37782506
37782506
44686240
44686240
44686242
44686242
45692550
45692550

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[(3,6-dimethylimidazo[2,1-b]thiazol-5-yl)methyl]-1-(1-piperidyl)propan-2-amine (2R)-N-[(3,6-dimethylimidazo[2,1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 8.54 -44.25 2 4 1 34 307.487 5 ↓

Analogs

37782507
37782507
37782508
37782508
37784384
37784384
37784385
37784385
45692555
45692555

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Popular Name: (2S)-N-[(6-methylimidazo[2,1-b]thiazol-5-yl)methyl]-1-(1-piperidyl)propan-2-amine (2S)-N-[(6-methylimidazo[2,1-b]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 8.43 -40.21 2 4 1 34 293.46 5 ↓

Analogs

37782507
37782507
37782508
37782508
45692555
45692555
45692558
45692558

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[(6-methylimidazo[2,1-b]thiazol-5-yl)methyl]-1-(1-piperidyl)propan-2-amine (2R)-N-[(6-methylimidazo[2,1-b]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 8.27 -44.55 2 4 1 34 293.46 5 ↓

Analogs

37782543
37782543
37782544
37782544
45692754
45692754
45692757
45692757

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-N-[(6-methoxyimidazo[2,1-b]thiazol-5-yl)methyl]-1-(1-piperidyl)propan-2-amine (2S)-N-[(6-methoxyimidazo[2,1-b]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 5.87 -37.92 2 5 1 43 309.459 6 ↓

Analogs

37782543
37782543
37782544
37782544
44686516
44686516
44686518
44686518
45692754
45692754

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-N-[(6-methoxyimidazo[2,1-b]thiazol-5-yl)methyl]-1-(1-piperidyl)propan-2-amine (2R)-N-[(6-methoxyimidazo[2,1-b]…

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Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 6.04 -40.19 2 5 1 43 309.459 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(6-methylimidazo[2,1-b]thiazol-5-yl)methyl]-2-(1-piperidyl)ethanamine N-[(6-methylimidazo[2,1-b]thiazo…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 7.31 -43.48 2 4 1 34 279.433 5 ↓

Parameters Provided:

ring.id = 510213
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 510213 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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