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ZINC Item

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19726976

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: Furo[3,2-b]pyridine-2-carboxylic acid, 3-amino-, ethyl ester (9CI) Furo[3,2-b]pyridine-2-carboxylic…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	2.86	-9.86	2	5	0	78	206.201	3	↓ MOL2 SDF SMILES Flexibase

58541956

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N'-(5-bromo-2-cyano-pyrimidin-4-yl)-N'-isobutyl-3-methyl-furo[3,2-b]pyridine-2-carbohydrazide N'-(5-bromo-2-cyano-pyrimidin-4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.01	8.79	-10.16	1	8	0	108	429.278	5	↓ MOL2 SDF SMILES Flexibase

15935056

Analogs

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Popular Name: 1-[2-[2-(4-methoxyphenyl)furo[4,5-b]pyridin-3-yl]ethynyl]cyclohexan-1-ol 1-[2-[2-(4-methoxyphenyl)furo[4,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.81	7.75	-13.19	1	4	0	55	347.414	2	↓ MOL2 SDF SMILES Flexibase

15935096

Analogs

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Popular Name: 4-[2-(3,5-dimethoxyphenyl)furo[4,5-b]pyridin-3-yl]but-3-yn-1-ol 4-[2-(3,5-dimethoxyphenyl)furo[4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	4.74	-14.49	1	5	0	65	323.348	4	↓ MOL2 SDF SMILES Flexibase

15935771

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[2-(4-methoxyphenyl)furo[4,5-b]pyridin-3-yl]prop-2-yn-1-ol 3-[2-(4-methoxyphenyl)furo[4,5-b…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.84	4.67	-16.06	1	4	0	55	279.295	2	↓ MOL2 SDF SMILES Flexibase

69485039

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl-(5-methylfuro[3,2-b]pyridin-2-yl)methanone 6,7-dihydro-4H-thieno[3,2-c]pyri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.36	7.14	-10.82	0	4	0	46	298.367	1	↓ MOL2 SDF SMILES Flexibase

69485956

Analogs

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Popular Name: N-(1-isopropylpyrazolo[3,4-b]pyridin-5-yl)-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-(1-isopropylpyrazolo[3,4-b]pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.29	6.44	-13.63	1	7	0	86	335.367	3	↓ MOL2 SDF SMILES Flexibase

69490032

Analogs

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Popular Name: (5-methylfuro[3,2-b]pyridin-2-yl)-[(2R)-2-[(2S)-1-methylpyrrolidin-2-yl]pyrrolidin-1-yl]methanone (5-methylfuro[3,2-b]pyridin-2-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	8.51	-37.52	1	5	1	51	314.409	2	↓ MOL2 SDF SMILES Flexibase

69490033

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-methylfuro[3,2-b]pyridin-2-yl)-[(2S)-2-[(2S)-1-methylpyrrolidin-2-yl]pyrrolidin-1-yl]methanone (5-methylfuro[3,2-b]pyridin-2-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	8.4	-40.68	1	5	1	51	314.409	2	↓ MOL2 SDF SMILES Flexibase

69490035

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-methylfuro[3,2-b]pyridin-2-yl)-[(2R)-2-[(2R)-1-methylpyrrolidin-2-yl]pyrrolidin-1-yl]methanone (5-methylfuro[3,2-b]pyridin-2-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	7.69	-40.84	1	5	1	51	314.409	2	↓ MOL2 SDF SMILES Flexibase

69490036

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-methylfuro[3,2-b]pyridin-2-yl)-[(2S)-2-[(2R)-1-methylpyrrolidin-2-yl]pyrrolidin-1-yl]methanone (5-methylfuro[3,2-b]pyridin-2-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	8.66	-37.66	1	5	1	51	314.409	2	↓ MOL2 SDF SMILES Flexibase

69491151

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2-methoxyphenyl)methyl]-N,5-dimethyl-furo[3,2-b]pyridine-2-carboxamide N-[(2-methoxyphenyl)methyl]-N,5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.50	7.5	-11.57	0	5	0	56	310.353	4	↓ MOL2 SDF SMILES Flexibase

69491175

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(3,4-dimethoxyphenyl)methyl]-N,5-dimethyl-furo[3,2-b]pyridine-2-carboxamide N-[(3,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.14	7.21	-15.32	0	6	0	65	340.379	5	↓ MOL2 SDF SMILES Flexibase

69491180

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N,5-dimethyl-N-[(1S)-1-(2-thienyl)ethyl]furo[3,2-b]pyridine-2-carboxamide N,5-dimethyl-N-[(1S)-1-(2-thieny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.95	7.45	-10.41	0	4	0	46	300.383	3	↓ MOL2 SDF SMILES Flexibase

69491183

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N,5-dimethyl-N-[(1R)-1-(2-thienyl)ethyl]furo[3,2-b]pyridine-2-carboxamide N,5-dimethyl-N-[(1R)-1-(2-thieny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.95	7.46	-10.46	0	4	0	46	300.383	3	↓ MOL2 SDF SMILES Flexibase

69509303

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-ethyl-2-[4-(5-methylfuro[3,2-b]pyridine-2-carbonyl)piperazin-1-yl]acetamide N-ethyl-2-[4-(5-methylfuro[3,2-b…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.97	2.89	-16.07	1	7	0	79	330.388	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	0.97	5.04	-51.44	2	7	1	80	331.396	4	↓ MOL2 SDF SMILES Flexibase

69510282

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [(2S)-2-[(2R)-1-ethylpyrrolidin-2-yl]pyrrolidin-1-yl]-(5-methylfuro[3,2-b]pyridin-2-yl)methanone [(2S)-2-[(2R)-1-ethylpyrrolidin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.28	8.09	-40.27	1	5	1	51	328.436	3	↓ MOL2 SDF SMILES Flexibase

69510288

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [(2S)-2-[(2S)-1-ethylpyrrolidin-2-yl]pyrrolidin-1-yl]-(5-methylfuro[3,2-b]pyridin-2-yl)methanone [(2S)-2-[(2S)-1-ethylpyrrolidin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.28	8.31	-38.89	1	5	1	51	328.436	3	↓ MOL2 SDF SMILES Flexibase

69519237

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N,N-diethyl-1-(5-methylfuro[3,2-b]pyridine-2-carbonyl)piperidine-4-carboxamide N,N-diethyl-1-(5-methylfuro[3,2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.97	7.74	-16.79	0	6	0	67	343.427	4	↓ MOL2 SDF SMILES Flexibase

69520068

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-methyl-N-[(3-ureidophenyl)methyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[(3-ureidophenyl)meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.36	1.89	-17.96	4	7	0	110	324.34	4	↓ MOL2 SDF SMILES Flexibase

69561149

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-methyl-N-[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[1-[2-(methylamino)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.03	2.03	-25.48	2	8	0	102	313.317	4	↓ MOL2 SDF SMILES Flexibase

69561421

Analogs

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Popular Name: N-[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]-N,5-dimethyl-furo[3,2-b]pyridine-2-carboxamide N-[(4-methoxy-3,5-dimethyl-2-pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.52	8.15	-34.26	1	6	1	70	340.403	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.52	6.92	-10.92	0	6	0	68	339.395	4	↓ MOL2 SDF SMILES Flexibase

69571578

Analogs

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Popular Name: N-(6-acetyl-1,3-benzodioxol-5-yl)-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-(6-acetyl-1,3-benzodioxol-5-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	5.25	-14.41	1	7	0	91	338.319	3	↓ MOL2 SDF SMILES Flexibase

69664351

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.66	8.66	-16.69	0	6	0	73	338.363	5	↓ MOL2 SDF SMILES Flexibase

69697703

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.46	6.61	-15.44	1	7	0	91	340.335	6	↓ MOL2 SDF SMILES Flexibase

69697709

Analogs

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Popular Name: 5-methyl-N-[2-(1,2,4-triazol-1-ylmethyl)phenyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[2-(1,2,4-triazol-1-y…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.62	9.13	-16.24	1	7	0	86	333.351	4	↓ MOL2 SDF SMILES Flexibase

69705285

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-methyl-N-[5-(2-pyridyl)-1,3,4-thiadiazol-2-yl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[5-(2-pyridyl)-1,3,4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.04	5.06	-17.68	1	7	0	94	337.364	3	↓ MOL2 SDF SMILES Flexibase

69738724

Analogs

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Popular Name: 5-methyl-N-[3-(6-oxo-1H-pyridazin-3-yl)phenyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[3-(6-oxo-1H-pyridazi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.79	2.97	-64.58	1	7	-1	104	345.338	3	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.33	4.81	-19.81	2	7	0	101	346.346	3	↓ MOL2 SDF SMILES Flexibase

69742416

Analogs

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Popular Name: N-(3-imidazol-1-ylphenyl)-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-(3-imidazol-1-ylphenyl)-5-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.06	8.1	-13.67	1	6	0	73	318.336	3	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	2.06	8.61	-42.58	2	6	1	74	319.344	3	↓ MOL2 SDF SMILES Flexibase

69776222

Analogs

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Popular Name: 5-methyl-N-[(1S)-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)butyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[(1S)-1-([1,2,4]triaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	8.18	-16.23	1	7	0	85	349.394	5	↓ MOL2 SDF SMILES Flexibase

69776224

Analogs

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Popular Name: 5-methyl-N-[(1R)-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)butyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[(1R)-1-([1,2,4]triaz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	8.18	-16.17	1	7	0	85	349.394	5	↓ MOL2 SDF SMILES Flexibase

69779484

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-methylfuro[3,2-b]pyridin-2-yl)-[(2R)-2-(pyrazol-1-ylmethyl)pyrrolidin-1-yl]methanone (5-methylfuro[3,2-b]pyridin-2-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.56	7.49	-14.94	0	6	0	64	310.357	3	↓ MOL2 SDF SMILES Flexibase

69779485

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (5-methylfuro[3,2-b]pyridin-2-yl)-[(2S)-2-(pyrazol-1-ylmethyl)pyrrolidin-1-yl]methanone (5-methylfuro[3,2-b]pyridin-2-yl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.56	6.94	-15.58	0	6	0	64	310.357	3	↓ MOL2 SDF SMILES Flexibase

69780600

Analogs

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Popular Name: N-[4-(1H-imidazol-2-yl)phenyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[4-(1H-imidazol-2-yl)phenyl]-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.65	6.24	-16.89	2	6	0	84	318.336	3	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.65	6.73	-39.27	3	6	1	85	319.344	3	↓ MOL2 SDF SMILES Flexibase

69807697

Analogs

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Popular Name: N-[[6-(2-methoxyethoxy)-3-pyridyl]methyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[[6-(2-methoxyethoxy)-3-pyridy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.30	2.71	-13.27	1	7	0	86	341.367	7	↓ MOL2 SDF SMILES Flexibase

69808626

Analogs

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Popular Name: 5-methyl-N-[3-(1,2,4-triazol-1-ylmethyl)phenyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[3-(1,2,4-triazol-1-y…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.64	8.8	-16.18	1	7	0	86	333.351	4	↓ MOL2 SDF SMILES Flexibase

69808697

Analogs

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Popular Name: 5-methyl-N-[4-(propanoylamino)phenyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[4-(propanoylamino)ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.60	5.43	-15.16	2	6	0	84	323.352	4	↓ MOL2 SDF SMILES Flexibase

69808749

Analogs

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Popular Name: 5-methyl-N-(6-pyrazol-1-yl-3-pyridyl)furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-(6-pyrazol-1-yl-3-pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	6.23	-14.22	1	7	0	86	319.324	3	↓ MOL2 SDF SMILES Flexibase

69813827

Analogs

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Popular Name: N-[(1S)-2-amino-1-benzyl-2-oxo-ethyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[(1S)-2-amino-1-benzyl-2-oxo-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	3.82	-18.18	3	6	0	98	323.352	5	↓ MOL2 SDF SMILES Flexibase

69813828

Analogs

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Popular Name: N-[(1R)-2-amino-1-benzyl-2-oxo-ethyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[(1R)-2-amino-1-benzyl-2-oxo-e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	3.82	-18.19	3	6	0	98	323.352	5	↓ MOL2 SDF SMILES Flexibase

69815389

Analogs

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Popular Name: 5-methyl-N-[4-(1,3,4-oxadiazol-2-yl)phenyl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[4-(1,3,4-oxadiazol-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.42	1.62	-16.78	1	7	0	94	320.308	3	↓ MOL2 SDF SMILES Flexibase

69844045

Analogs

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Popular Name: N-[1-(2-diethylaminoethyl)pyrazol-4-yl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[1-(2-diethylaminoethyl)pyrazo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.71	6.96	-48.1	2	7	1	77	342.423	7	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	1.71	4.81	-13.47	1	7	0	76	341.415	7	↓ MOL2 SDF SMILES Flexibase

69846894

Analogs

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Popular Name: N-[(1R,2R)-2-(2-methoxyphenyl)cyclopropyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[(1R,2R)-2-(2-methoxyphenyl)cy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	6.77	-12.07	1	5	0	64	322.364	4	↓ MOL2 SDF SMILES Flexibase

69846896

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2R)-2-(2-methoxyphenyl)cyclopropyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[(1S,2R)-2-(2-methoxyphenyl)cy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	6.59	-12.51	1	5	0	64	322.364	4	↓ MOL2 SDF SMILES Flexibase

69846898

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2S)-2-(2-methoxyphenyl)cyclopropyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[(1R,2S)-2-(2-methoxyphenyl)cy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	6.59	-12.52	1	5	0	64	322.364	4	↓ MOL2 SDF SMILES Flexibase

69846901

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2S)-2-(2-methoxyphenyl)cyclopropyl]-5-methyl-furo[3,2-b]pyridine-2-carboxamide N-[(1S,2S)-2-(2-methoxyphenyl)cy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	6.78	-12.1	1	5	0	64	322.364	4	↓ MOL2 SDF SMILES Flexibase

69847554

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-methoxyethyl)-5-methyl-N-(2-pyridylmethyl)furo[3,2-b]pyridine-2-carboxamide N-(2-methoxyethyl)-5-methyl-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.31	6.29	-16.22	0	6	0	68	325.368	6	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	1.31	6.71	-39.06	1	6	1	70	326.376	6	↓ MOL2 SDF SMILES Flexibase

69871704

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-methyl-N-[1-(4-pyridylmethyl)pyrazol-3-yl]furo[3,2-b]pyridine-2-carboxamide 5-methyl-N-[1-(4-pyridylmethyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.43	6.52	-15.73	1	7	0	86	333.351	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	1.43	6.98	-44.47	2	7	1	87	334.359	4	↓ MOL2 SDF SMILES Flexibase

69872731

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2,4-dimethoxyphenyl)methyl]-N,5-dimethyl-furo[3,2-b]pyridine-2-carboxamide N-[(2,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.53	6.79	-12.31	0	6	0	65	340.379	5	↓ MOL2 SDF SMILES Flexibase

69874720

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-cyanoethyl)-5-methyl-N-(p-tolyl)furo[3,2-b]pyridine-2-carboxamide N-(2-cyanoethyl)-5-methyl-N-(p-t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.70	9.18	-11.61	0	5	0	70	319.364	4	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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