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Analogs

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Popular Name: 2-(3,3-dimethylmorpholin-4-yl)imidazo[1,2-a]pyridine-3-carbaldehyde 2-(3,3-dimethylmorpholin-4-yl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.21 6.24 -10.18 0 5 0 47 259.309 2 ↓

Analogs

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Popular Name: 2-(3,3-dimethylmorpholin-4-yl)imidazo[1,2-a]pyridine-3-carboxylic 2-(3,3-dimethylmorpholin-4-yl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.99 5.94 -57.37 0 6 -1 70 274.3 2 ↓
Lo Low (pH 4.5-6) 1.99 7.43 -32.05 1 6 0 71 275.308 2 ↓

Analogs

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Popular Name: [2-(3,3-dimethylmorpholin-4-yl)imidazo[1,2-a]pyridin-3-yl]methanol [2-(3,3-dimethylmorpholin-4-yl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 3.92 -12.32 1 5 0 50 261.325 2 ↓
Lo Low (pH 4.5-6) 1.76 4.69 -29.74 2 5 1 51 262.333 2 ↓

Analogs

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Popular Name: 4-[3-(chloromethyl)imidazo[1,2-a]pyridin-2-yl]-3,3-dimethyl-morpholine 4-[3-(chloromethyl)imidazo[1,2-a…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.00 7.88 -9.6 0 4 0 30 279.771 2 ↓
Lo Low (pH 4.5-6) 3.00 8.64 -28.95 1 4 1 31 280.779 2 ↓

Analogs

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Popular Name: [2-(3,3-dimethylmorpholin-4-yl)imidazo[1,2-a]pyridin-3-yl]methanamine [2-(3,3-dimethylmorpholin-4-yl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.61 4.66 -56.76 3 5 1 57 261.349 2 ↓
Hi High (pH 8-9.5) 1.61 4.25 -9.45 2 5 0 56 260.341 2 ↓

Analogs

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Popular Name: 1-[2-(3,3-dimethylmorpholin-4-yl)imidazo[1,2-a]pyridin-3-yl]-N-methyl-methanamine 1-[2-(3,3-dimethylmorpholin-4-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 6.53 -50.48 2 5 1 46 275.376 3 ↓
Hi High (pH 8-9.5) 1.98 5.07 -9.21 1 5 0 42 274.368 3 ↓

Analogs

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Popular Name: N-[[2-(3,3-dimethylmorpholin-4-yl)imidazo[1,2-a]pyridin-3-yl]methyl]ethanamine N-[[2-(3,3-dimethylmorpholin-4-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.36 7.41 -49.11 2 5 1 46 289.403 4 ↓
Hi High (pH 8-9.5) 2.36 6.04 -8.58 1 5 0 42 288.395 4 ↓

Parameters Provided:

ring.id = 541496
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 541496 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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