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Analogs

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Popular Name: 1-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]-3-phenyl-imidazolidin-2-one 1-[2-oxo-2-(3,4,6,7-tetrahydroim…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 8.49 -52.14 2 7 1 74 326.38 3 ↓
Mid Mid (pH 6-8) 1.05 8.02 -21.75 1 7 0 73 325.372 3 ↓

Analogs

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Popular Name: 1-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]-3-(p-tolyl)imidazolidin-2-one 1-[2-oxo-2-(3,4,6,7-tetrahydroim…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.50 9.16 -52.09 2 7 1 74 340.407 3 ↓
Mid Mid (pH 6-8) 1.50 8.7 -21.82 1 7 0 73 339.399 3 ↓

Analogs

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Popular Name: 1-(4-fluorophenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2-one 1-(4-fluorophenyl)-3-[2-oxo-2-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.22 8.56 -52.33 2 7 1 74 344.37 3 ↓
Mid Mid (pH 6-8) 1.22 8.09 -21.23 1 7 0 73 343.362 3 ↓

Analogs

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Popular Name: 1-(2-fluorophenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2-one 1-(2-fluorophenyl)-3-[2-oxo-2-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.17 8.84 -52.61 2 7 1 74 344.37 3 ↓
Mid Mid (pH 6-8) 1.17 8.37 -22.55 1 7 0 73 343.362 3 ↓

Analogs

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Popular Name: 1-(3-chlorophenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2-one 1-(3-chlorophenyl)-3-[2-oxo-2-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 9.01 -51.1 2 7 1 74 360.825 3 ↓
Mid Mid (pH 6-8) 1.71 8.54 -19.49 1 7 0 73 359.817 3 ↓

Analogs

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Popular Name: 1-(4-chlorophenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2-one 1-(4-chlorophenyl)-3-[2-oxo-2-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.73 9.01 -51.83 2 7 1 74 360.825 3 ↓
Mid Mid (pH 6-8) 1.73 8.54 -20.67 1 7 0 73 359.817 3 ↓

Analogs

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Popular Name: 1-(3,4-difluorophenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2 1-(3,4-difluorophenyl)-3-[2-oxo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 8.61 -52.22 2 7 1 74 362.36 3 ↓
Mid Mid (pH 6-8) 1.31 8.14 -19.62 1 7 0 73 361.352 3 ↓

Analogs

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Popular Name: 1-(4-methoxyphenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2-on 1-(4-methoxyphenyl)-3-[2-oxo-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.11 7.78 -52.99 2 8 1 83 356.406 4 ↓
Mid Mid (pH 6-8) 1.11 7.31 -22.07 1 8 0 82 355.398 4 ↓

Analogs

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Popular Name: 1-(2-methoxyphenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2-on 1-(2-methoxyphenyl)-3-[2-oxo-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 8.13 -53.23 2 8 1 83 356.406 4 ↓
Mid Mid (pH 6-8) 1.06 7.66 -23.28 1 8 0 82 355.398 4 ↓

Analogs

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Popular Name: 1-(4-ethoxyphenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2-one 1-(4-ethoxyphenyl)-3-[2-oxo-2-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.49 8.71 -52.8 2 8 1 83 370.433 5 ↓
Mid Mid (pH 6-8) 1.49 8.24 -21.91 1 8 0 82 369.425 5 ↓

Analogs

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Popular Name: 1-(3,4-dimethoxyphenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin- 1-(3,4-dimethoxyphenyl)-3-[2-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.70 7.69 -55.29 2 9 1 92 386.432 5 ↓
Mid Mid (pH 6-8) 0.70 7.22 -23.77 1 9 0 91 385.424 5 ↓

Analogs

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Popular Name: 1-(2,5-dimethoxyphenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin- 1-(2,5-dimethoxyphenyl)-3-[2-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 7.42 -54.97 2 9 1 92 386.432 5 ↓
Mid Mid (pH 6-8) 1.10 6.96 -25.11 1 9 0 91 385.424 5 ↓

Analogs

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Popular Name: 1-(4-isopropylphenyl)-3-[2-oxo-2-(3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl)ethyl]imidazolidin-2- 1-(4-isopropylphenyl)-3-[2-oxo-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 10.41 -51.7 2 7 1 74 368.461 4 ↓
Mid Mid (pH 6-8) 2.57 9.94 -21.45 1 7 0 73 367.453 4 ↓

Parameters Provided:

ring.id = 558496
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 558496 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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