UCSF
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45632063
45632063
45632065
45632065
45632067
45632067
45632069
45632069

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Popular Name: N-(2,4-dimethoxyphenyl)-2-[(4S)-2,5-dioxo-4-phenyl-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetamid N-(2,4-dimethoxyphenyl)-2-[(4S)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 6.67 -20.3 2 9 0 106 423.425 6 ↓

Analogs

45632063
45632063
45632065
45632065
45632067
45632067
45632069
45632069

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethoxyphenyl)-2-[(4R)-2,5-dioxo-4-phenyl-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetamid N-(2,4-dimethoxyphenyl)-2-[(4R)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 6.67 -20.39 2 9 0 106 423.425 6 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-phenyl-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2-methoxy-5-methyl-phenyl)ac 2-[(4S)-2,5-dioxo-4-phenyl-4,7-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.49 8.06 -19.89 2 8 0 97 407.426 5 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-phenyl-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2-methoxy-5-methyl-phenyl)ac 2-[(4R)-2,5-dioxo-4-phenyl-4,7-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.49 8.07 -19.93 2 8 0 97 407.426 5 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(m-tolyl)acetamide 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 9.39 -21.26 2 7 0 88 391.427 4 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(m-tolyl)acetamide 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 9.38 -21.43 2 7 0 88 391.427 4 ↓

Analogs

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Popular Name: N-(3,4-dimethylphenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(3,4-dimethylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 9.93 -21.41 2 7 0 88 405.454 4 ↓

Analogs

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Popular Name: N-(3,4-dimethylphenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(3,4-dimethylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 9.92 -21.52 2 7 0 88 405.454 4 ↓

Analogs

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Popular Name: N-(3,5-dimethylphenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(3,5-dimethylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 10.06 -21.11 2 7 0 88 405.454 4 ↓

Analogs

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Popular Name: N-(3,5-dimethylphenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(3,5-dimethylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 10.05 -21.27 2 7 0 88 405.454 4 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2,4,6-trimethylphenyl)ace 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 10.96 -20.23 2 7 0 88 419.481 4 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2,4,6-trimethylphenyl)ace 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 10.96 -20.36 2 7 0 88 419.481 4 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(4-ethylphenyl)acetamide 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.42 10.08 -21.25 2 7 0 88 405.454 5 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(4-ethylphenyl)acetamide 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.42 10.09 -21.34 2 7 0 88 405.454 5 ↓

Analogs

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Popular Name: N-(2,4-dimethylphenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(2,4-dimethylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 10.21 -20.49 2 7 0 88 405.454 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethylphenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(2,4-dimethylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 10.21 -20.78 2 7 0 88 405.454 4 ↓

Analogs

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Popular Name: N-(2,5-dimethylphenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(2,5-dimethylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 10.21 -20.55 2 7 0 88 405.454 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethylphenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(2,5-dimethylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 10.21 -20.6 2 7 0 88 405.454 4 ↓

Analogs

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Popular Name: N-(2,6-dimethylphenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(2,6-dimethylphenyl)-2-[(4R)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 10.3 -20.15 2 7 0 88 405.454 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,6-dimethylphenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]acetam N-(2,6-dimethylphenyl)-2-[(4S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 10.3 -20.25 2 7 0 88 405.454 4 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(4-methoxyphenyl)acetamide 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 8 -22.25 2 8 0 97 407.426 5 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(4-methoxyphenyl)acetamide 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 8 -22.42 2 8 0 97 407.426 5 ↓

Analogs

45632063
45632063
45632065
45632065
45632067
45632067
45632069
45632069

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethoxyphenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]aceta N-(2,4-dimethoxyphenyl)-2-[(4R)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 7.39 -20.28 2 9 0 106 437.452 6 ↓

Analogs

45632063
45632063
45632065
45632065
45632067
45632067
45632069
45632069

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethoxyphenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]aceta N-(2,4-dimethoxyphenyl)-2-[(4S)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 7.4 -20.38 2 9 0 106 437.452 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-dimethoxyphenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]aceta N-(3,4-dimethoxyphenyl)-2-[(4R)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.15 7.91 -24.3 2 9 0 106 437.452 6 ↓

Analogs

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Popular Name: N-(3,4-dimethoxyphenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]aceta N-(3,4-dimethoxyphenyl)-2-[(4S)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.15 7.9 -24.4 2 9 0 106 437.452 6 ↓

Analogs

45632063
45632063
45632065
45632065
45632067
45632067
45632069
45632069

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2-ethoxyphenyl)acetamide 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.89 8.99 -19.69 2 8 0 97 421.453 6 ↓

Analogs

45632063
45632063
45632065
45632065
45632067
45632067
45632069
45632069

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2-ethoxyphenyl)acetamide 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.89 9 -19.88 2 8 0 97 421.453 6 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(4-ethoxyphenyl)acetamide 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.94 8.87 -22.21 2 8 0 97 421.453 6 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(4-ethoxyphenyl)acetamide 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.94 8.88 -22.3 2 8 0 97 421.453 6 ↓

Analogs

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Popular Name: N-(3-chloro-4-fluoro-phenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(3-chloro-4-fluoro-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 9.28 -25.09 2 7 0 88 429.835 4 ↓

Analogs

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Popular Name: N-(3-chloro-4-fluoro-phenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(3-chloro-4-fluoro-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 9.27 -25.15 2 7 0 88 429.835 4 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-[2-(trifluoromethyl)phenyl 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 9.94 -18.56 2 7 0 88 445.397 5 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-[2-(trifluoromethyl)phenyl 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 9.95 -18.69 2 7 0 88 445.397 5 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2-fluoro-4-methyl-phenyl) 2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 9.48 -18.38 2 7 0 88 409.417 4 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2-fluoro-4-methyl-phenyl) 2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 9.48 -18.55 2 7 0 88 409.417 4 ↓

Analogs

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Popular Name: N-(3-chloro-2-methyl-phenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(3-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.54 9.98 -20.17 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(3-chloro-2-methyl-phenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(3-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.54 9.98 -20.18 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(5-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 10.06 -21.88 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(5-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 10.07 -22 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(2-chloro-4-methyl-phenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(2-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 10.01 -18.03 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(2-chloro-4-methyl-phenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(2-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 10.01 -18.15 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(3-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 9.82 -23.53 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl] N-(3-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 9.81 -23.59 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: N-(3-chloro-4-methoxy-phenyl)-2-[(4R)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl N-(3-chloro-4-methoxy-phenyl)-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 8.56 -25.85 2 8 0 97 441.871 5 ↓

Analogs

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Popular Name: N-(3-chloro-4-methoxy-phenyl)-2-[(4S)-2,5-dioxo-4-(p-tolyl)-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl N-(3-chloro-4-methoxy-phenyl)-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 8.57 -25.99 2 8 0 97 441.871 5 ↓

Analogs

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Popular Name: 2-[(4S)-4-(3-chlorophenyl)-2,5-dioxo-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2,4,6-trimethylphe 2-[(4S)-4-(3-chlorophenyl)-2,5-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 10.73 -21.3 2 7 0 88 439.899 4 ↓

Analogs

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Popular Name: 2-[(4R)-4-(3-chlorophenyl)-2,5-dioxo-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2,4,6-trimethylphe 2-[(4R)-4-(3-chlorophenyl)-2,5-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.98 10.74 -20.11 2 7 0 88 439.899 4 ↓

Analogs

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Popular Name: 2-[(4S)-4-(3-chlorophenyl)-2,5-dioxo-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2,5-dimethylphenyl 2-[(4S)-4-(3-chlorophenyl)-2,5-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.54 9.99 -21.31 2 7 0 88 425.872 4 ↓

Analogs

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Popular Name: 2-[(4R)-4-(3-chlorophenyl)-2,5-dioxo-4,7-dihydro-3H-furo[3,4-d]pyrimidin-1-yl]-N-(2,5-dimethylphenyl 2-[(4R)-4-(3-chlorophenyl)-2,5-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.54 10 -20.21 2 7 0 88 425.872 4 ↓

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