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Analogs

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Popular Name: 2-methyl-1-(5-methylthiazol-2-yl)-6,7-dihydro-5H-indol-4-one 2-methyl-1-(5-methylthiazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 8.5 -10.36 0 3 0 35 246.335 1 ↓

Analogs

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Popular Name: 1-(5-methylthiazol-2-yl)-6,7-dihydro-5H-indol-4-one 1-(5-methylthiazol-2-yl)-6,7-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.17 8.25 -9.82 0 3 0 35 232.308 1 ↓

Analogs

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Popular Name: 2,6,6-trimethyl-1-(5-methylthiazol-2-yl)-5,7-dihydroindol-4-one 2,6,6-trimethyl-1-(5-methylthiaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 9.43 -9.77 0 3 0 35 274.389 1 ↓

Analogs

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Popular Name: 6,6-dimethyl-1-(5-methylthiazol-2-yl)-5,7-dihydroindol-4-one 6,6-dimethyl-1-(5-methylthiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 9.19 -9.3 0 3 0 35 260.362 1 ↓

Analogs

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Popular Name: 2-methyl-1-thiazol-2-yl-6,7-dihydro-5H-indol-4-one 2-methyl-1-thiazol-2-yl-6,7-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.17 7.67 -10.57 0 3 0 35 232.308 1 ↓

Analogs

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Popular Name: 1-thiazol-2-yl-6,7-dihydro-5H-indol-4-one 1-thiazol-2-yl-6,7-dihydro-5H-in…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 7.43 -10.17 0 3 0 35 218.281 1 ↓

Analogs

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Popular Name: 2,6,6-trimethyl-1-thiazol-2-yl-5,7-dihydroindol-4-one 2,6,6-trimethyl-1-thiazol-2-yl-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 8.6 -10.03 0 3 0 35 260.362 1 ↓

Analogs

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Popular Name: 6,6-dimethyl-1-thiazol-2-yl-5,7-dihydroindol-4-one 6,6-dimethyl-1-thiazol-2-yl-5,7-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 8.35 -9.57 0 3 0 35 246.335 1 ↓

Analogs

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Popular Name: 2-methyl-1-(4-methylthiazol-2-yl)-6,7-dihydro-5H-indol-4-one 2-methyl-1-(4-methylthiazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.39 8.52 -12.25 0 3 0 35 246.335 1 ↓

Analogs

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Popular Name: 1-(4-methylthiazol-2-yl)-6,7-dihydro-5H-indol-4-one 1-(4-methylthiazol-2-yl)-6,7-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.17 7.59 -12.39 0 3 0 35 232.308 1 ↓

Analogs

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Popular Name: 2,6,6-trimethyl-1-(4-methylthiazol-2-yl)-5,7-dihydroindol-4-one 2,6,6-trimethyl-1-(4-methylthiaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 9.44 -11.43 0 3 0 35 274.389 1 ↓

Analogs

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Popular Name: 6,6-dimethyl-1-(4-methylthiazol-2-yl)-5,7-dihydroindol-4-one 6,6-dimethyl-1-(4-methylthiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 8.52 -11.56 0 3 0 35 260.362 1 ↓

Analogs

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Popular Name: 1-(5-bromothiazol-2-yl)-2-methyl-6,7-dihydro-5H-indol-4-one 1-(5-bromothiazol-2-yl)-2-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.10 8.41 -8.18 0 3 0 35 311.204 1 ↓

Analogs

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Popular Name: 1-(5-bromothiazol-2-yl)-6,7-dihydro-5H-indol-4-one 1-(5-bromothiazol-2-yl)-6,7-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 8.15 -7.81 0 3 0 35 297.177 1 ↓

Analogs

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Popular Name: 1-(5-bromothiazol-2-yl)-2,6,6-trimethyl-5,7-dihydroindol-4-one 1-(5-bromothiazol-2-yl)-2,6,6-tr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.99 9.34 -7.67 0 3 0 35 339.258 1 ↓

Analogs

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Popular Name: 1-(5-bromothiazol-2-yl)-6,6-dimethyl-5,7-dihydroindol-4-one 1-(5-bromothiazol-2-yl)-6,6-dime…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.76 9.08 -7.28 0 3 0 35 325.231 1 ↓

Analogs

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Popular Name: 1-(4-tert-butylthiazol-2-yl)-2-methyl-6,7-dihydro-5H-indol-4-one 1-(4-tert-butylthiazol-2-yl)-2-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.11 10.54 -11.61 0 3 0 35 288.416 2 ↓

Analogs

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Popular Name: 1-(4-tert-butylthiazol-2-yl)-6,7-dihydro-5H-indol-4-one 1-(4-tert-butylthiazol-2-yl)-6,7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.89 9.62 -11.82 0 3 0 35 274.389 2 ↓

Analogs

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Popular Name: 1-(4-tert-butylthiazol-2-yl)-6,6-dimethyl-5,7-dihydroindol-4-one 1-(4-tert-butylthiazol-2-yl)-6,6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.78 10.53 -10.98 0 3 0 35 302.443 2 ↓

Analogs

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Popular Name: 1-(4-isopropylthiazol-2-yl)-2-methyl-6,7-dihydro-5H-indol-4-one 1-(4-isopropylthiazol-2-yl)-2-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 9.79 -11.95 0 3 0 35 274.389 2 ↓

Analogs

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Popular Name: 1-(4-isopropylthiazol-2-yl)-6,7-dihydro-5H-indol-4-one 1-(4-isopropylthiazol-2-yl)-6,7-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.22 8.86 -12.08 0 3 0 35 260.362 2 ↓

Analogs

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Popular Name: 1-(4-isopropylthiazol-2-yl)-2,6,6-trimethyl-5,7-dihydroindol-4-one 1-(4-isopropylthiazol-2-yl)-2,6,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.33 10.71 -11.12 0 3 0 35 302.443 2 ↓

Analogs

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Popular Name: 1-(4-isopropylthiazol-2-yl)-6,6-dimethyl-5,7-dihydroindol-4-one 1-(4-isopropylthiazol-2-yl)-6,6-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.11 9.79 -11.23 0 3 0 35 288.416 2 ↓

Parameters Provided:

ring.id = 569362
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 569362 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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