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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

11839518
11839518

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Popular Name: N-[[(3S)-8-[(2-fluorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-3-methyl-butanamide N-[[(3S)-8-[(2-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 -0.22 -38.71 2 4 1 43 363.497 6 ↓

Analogs

11839517
11839517

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Popular Name: N-[[(3R)-8-[(2-fluorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-3-methyl-butanamide N-[[(3R)-8-[(2-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 -0.17 -41.29 2 4 1 43 363.497 6 ↓

Analogs

11975532
11975532
12035891
12035891
12035894
12035894

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Popular Name: N-[[(2S)-8-[(2,5-dimethylphenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]-2-methoxy-acetamide N-[[(2S)-8-[(2,5-dimethylphenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.49 -0.81 -45.1 2 5 1 52 361.506 6 ↓

Analogs

12035891
12035891
12035894
12035894
11975527
11975527

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Popular Name: N-[[(2R)-8-[(2,5-dimethylphenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]-2-methoxy-acetamide N-[[(2R)-8-[(2,5-dimethylphenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.49 -0.81 -48.45 2 5 1 52 361.506 6 ↓

Analogs

11997666
11997666

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Popular Name: N-[[(3S)-8-[(2-methoxyphenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]acetamide N-[[(3S)-8-[(2-methoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.73 -1.4 -39.99 2 5 1 52 333.452 5 ↓

Analogs

11997662
11997662

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Popular Name: N-[[(3R)-8-[(2-methoxyphenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]acetamide N-[[(3R)-8-[(2-methoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.73 -1.22 -41.98 2 5 1 52 333.452 5 ↓

Analogs

11998571
11998571

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Popular Name: N-[[(3S)-8-[(2-allyloxyphenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-2-methyl-propanamide N-[[(3S)-8-[(2-allyloxyphenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 -0.48 -39.62 2 5 1 52 387.544 8 ↓

Analogs

11998570
11998570

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Popular Name: N-[[(3R)-8-[(2-allyloxyphenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-2-methyl-propanamide N-[[(3R)-8-[(2-allyloxyphenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 -0.3 -41.83 2 5 1 52 387.544 8 ↓

Analogs

12000533
12000533

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Popular Name: 2-methoxy-N-[[(3S)-8-[(2,3,6-trifluorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]acetamid 2-methoxy-N-[[(3S)-8-[(2,3,6-tri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.01 0.44 -43.8 2 5 1 52 387.422 6 ↓

Analogs

12000525
12000525

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Popular Name: 2-methoxy-N-[[(3R)-8-[(2,3,6-trifluorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]acetamid 2-methoxy-N-[[(3R)-8-[(2,3,6-tri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.01 0.36 -46.13 2 5 1 52 387.422 6 ↓

Analogs

12034489
12034489

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Popular Name: N-[[(3S)-8-[(3-fluorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]acetamide N-[[(3S)-8-[(3-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.86 -0.78 -49 2 4 1 43 321.416 4 ↓

Analogs

12034488
12034488

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Popular Name: N-[[(3R)-8-[(3-fluorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]acetamide N-[[(3R)-8-[(3-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.86 -0.65 -48.7 2 4 1 43 321.416 4 ↓

Analogs

12035125
12035125

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Popular Name: N-[[(3S)-8-[(2,5-dimethoxyphenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-2-methoxy-acetamide N-[[(3S)-8-[(2,5-dimethoxyphenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 -1.45 -42.77 2 7 1 70 393.504 8 ↓

Analogs

12035122
12035122

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Popular Name: N-[[(3R)-8-[(2,5-dimethoxyphenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-2-methoxy-acetamide N-[[(3R)-8-[(2,5-dimethoxyphenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 -1.39 -41.71 2 7 1 70 393.504 8 ↓

Analogs

12035894
12035894
11975527
11975527
11975532
11975532

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Popular Name: 2-methoxy-N-[[(2S)-8-[(2,4,5-trimethylphenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]acetamid 2-methoxy-N-[[(2S)-8-[(2,4,5-tri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 -0.52 -44.99 2 5 1 52 375.533 6 ↓

Analogs

11975527
11975527
11975532
11975532
12035891
12035891

Draw Identity 99% 90% 80% 70%

Popular Name: 2-methoxy-N-[[(2R)-8-[(2,4,5-trimethylphenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]acetamid 2-methoxy-N-[[(2R)-8-[(2,4,5-tri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 -0.53 -48.25 2 5 1 52 375.533 6 ↓

Analogs

12040764
12040764

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Popular Name: N-[[(3S)-8-[(3-chlorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-2-methyl-propanamide N-[[(3S)-8-[(3-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 -1.21 -46 2 4 1 43 365.925 5 ↓

Analogs

12040761
12040761

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Popular Name: N-[[(3R)-8-[(3-chlorophenyl)methyl]-4-oxa-8-azaspiro[4.5]decan-3-yl]methyl]-2-methyl-propanamide N-[[(3R)-8-[(3-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 -1.16 -44.4 2 4 1 43 365.925 5 ↓

Analogs

12040842
12040842

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Popular Name: N-[[(2S)-8-[(4-isobutylphenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]acetamide N-[[(2S)-8-[(4-isobutylphenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 -0.64 -44.04 2 4 1 43 359.534 6 ↓

Analogs

12040834
12040834

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Popular Name: N-[[(2R)-8-[(4-isobutylphenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]acetamide N-[[(2R)-8-[(4-isobutylphenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 -0.55 -41.49 2 4 1 43 359.534 6 ↓

Analogs

12210976
12210976

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Popular Name: N-[[(2S)-8-[(4-methoxy-3-methyl-phenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]-2-methyl-prop N-[[(2S)-8-[(4-methoxy-3-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 -0.64 -45.17 2 5 1 52 375.533 6 ↓

Analogs

12210973
12210973

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Popular Name: N-[[(2R)-8-[(4-methoxy-3-methyl-phenyl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]-2-methyl-prop N-[[(2R)-8-[(4-methoxy-3-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 -0.73 -47.59 2 5 1 52 375.533 6 ↓

Parameters Provided:

ring.id = 58339
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 58339 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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