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Analogs

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Popular Name: (5R)-1-isopentyl-N-(2-methoxyphenyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-carboxami (5R)-1-isopentyl-N-(2-methoxyphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.37 2.54 -18.45 3 9 0 126 400.435 6 ↓
Ref Reference (pH 7) 1.82 3.26 -42.47 2 9 -1 129 399.427 6 ↓

Analogs

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Popular Name: (5S)-1-isopentyl-N-(2-methoxyphenyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-carboxami (5S)-1-isopentyl-N-(2-methoxyphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.37 2.5 -18.52 3 9 0 126 400.435 6 ↓
Ref Reference (pH 7) 1.82 4.34 -39.05 2 9 -1 129 399.427 6 ↓

Analogs

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Popular Name: (5R)-1-isopentyl-N-(3-methylsulfanylphenyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-ca (5R)-1-isopentyl-N-(3-methylsulf…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 4.12 -21.67 3 8 0 117 416.503 6 ↓
Ref Reference (pH 7) 2.22 4.84 -46.1 2 8 -1 119 415.495 6 ↓

Analogs

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Popular Name: (5S)-1-isopentyl-N-(3-methylsulfanylphenyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-ca (5S)-1-isopentyl-N-(3-methylsulf…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 4.12 -21.6 3 8 0 117 416.503 6 ↓
Ref Reference (pH 7) 2.22 5.98 -39.64 2 8 -1 119 415.495 6 ↓

Analogs

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Popular Name: (5R)-N-(3,4-difluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5 (5R)-N-(3,4-difluorophenyl)-1-(2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.05 0.56 -19.75 3 9 0 126 394.334 5 ↓
Ref Reference (pH 7) 0.40 1.3 -38.28 2 9 -1 129 393.326 5 ↓

Analogs

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Popular Name: (5S)-N-(3,4-difluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5 (5S)-N-(3,4-difluorophenyl)-1-(2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.05 0.56 -22.54 3 9 0 126 394.334 5 ↓
Ref Reference (pH 7) 0.40 2.41 -38.06 2 9 -1 129 393.326 5 ↓

Analogs

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Popular Name: (5R)-N-(4-fluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5R)-N-(4-fluorophenyl)-1-(2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.14 0.5 -20.81 3 9 0 126 376.344 5 ↓
Ref Reference (pH 7) 0.31 1.25 -40.82 2 9 -1 129 375.336 5 ↓

Analogs

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Popular Name: (5S)-N-(4-fluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5S)-N-(4-fluorophenyl)-1-(2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.14 0.51 -19.35 3 9 0 126 376.344 5 ↓
Ref Reference (pH 7) 0.31 2.36 -36.74 2 9 -1 129 375.336 5 ↓

Analogs

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Popular Name: (5R)-N-(3-fluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5R)-N-(3-fluorophenyl)-1-(2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.17 0.5 -18.63 3 9 0 126 376.344 5 ↓
Ref Reference (pH 7) 0.28 1.25 -40.23 2 9 -1 129 375.336 5 ↓

Analogs

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Popular Name: (5S)-N-(3-fluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5S)-N-(3-fluorophenyl)-1-(2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.17 0.51 -21.41 3 9 0 126 376.344 5 ↓
Ref Reference (pH 7) 0.28 2.37 -39.88 2 9 -1 129 375.336 5 ↓

Analogs

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Popular Name: (5R)-1-isopentyl-2,4,7-trioxo-N-[4-(trifluoromethoxy)phenyl]-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine- (5R)-1-isopentyl-2,4,7-trioxo-N-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 2.9 -19.33 3 9 0 126 454.405 7 ↓
Ref Reference (pH 7) 2.78 3.62 -37.24 2 9 -1 129 453.397 7 ↓

Analogs

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Popular Name: (5S)-1-isopentyl-2,4,7-trioxo-N-[4-(trifluoromethoxy)phenyl]-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine- (5S)-1-isopentyl-2,4,7-trioxo-N-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 2.88 -20.12 3 9 0 126 454.405 7 ↓
Ref Reference (pH 7) 2.78 4.73 -34.51 2 9 -1 129 453.397 7 ↓

Analogs

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Popular Name: (5R)-1-isopentyl-2,4,7-trioxo-N-(2,3,4-trifluorophenyl)-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5R)-1-isopentyl-2,4,7-trioxo-N-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 3.35 -17.59 3 8 0 117 424.379 5 ↓
Ref Reference (pH 7) 2.16 4.06 -33.59 2 8 -1 119 423.371 5 ↓

Analogs

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Popular Name: (5S)-1-isopentyl-2,4,7-trioxo-N-(2,3,4-trifluorophenyl)-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5S)-1-isopentyl-2,4,7-trioxo-N-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 3.33 -17.83 3 8 0 117 424.379 5 ↓
Ref Reference (pH 7) 2.16 5.17 -32.45 2 8 -1 119 423.371 5 ↓

Analogs

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Popular Name: (5R)-1-(2-methoxyethyl)-2,4,7-trioxo-N-[2-(trifluoromethyl)phenyl]-6,8-dihydro-5H-pyrido[2,3-d]pyrim (5R)-1-(2-methoxyethyl)-2,4,7-tr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 1.69 -17.1 3 9 0 126 426.351 6 ↓
Ref Reference (pH 7) 0.99 2.41 -41.28 2 9 -1 129 425.343 6 ↓

Analogs

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Popular Name: (5S)-1-(2-methoxyethyl)-2,4,7-trioxo-N-[2-(trifluoromethyl)phenyl]-6,8-dihydro-5H-pyrido[2,3-d]pyrim (5S)-1-(2-methoxyethyl)-2,4,7-tr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 1.69 -15.47 3 9 0 126 426.351 6 ↓
Ref Reference (pH 7) 0.99 3.57 -38.85 2 9 -1 129 425.343 6 ↓

Analogs

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Popular Name: (5R)-N-(2-fluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5R)-N-(2-fluorophenyl)-1-(2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.19 0.58 -17.89 3 9 0 126 376.344 5 ↓
Ref Reference (pH 7) 0.26 1.29 -42.13 2 9 -1 129 375.336 5 ↓

Analogs

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Popular Name: (5S)-N-(2-fluorophenyl)-1-(2-methoxyethyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-car (5S)-N-(2-fluorophenyl)-1-(2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.19 0.55 -17.35 3 9 0 126 376.344 5 ↓
Ref Reference (pH 7) 0.26 2.39 -39.57 2 9 -1 129 375.336 5 ↓

Analogs

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Popular Name: (5R)-1-isopentyl-N-(3-methoxyphenyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-carboxami (5R)-1-isopentyl-N-(3-methoxyphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.40 2.4 -22.06 3 9 0 126 400.435 6 ↓
Ref Reference (pH 7) 1.84 3.11 -46.35 2 9 -1 129 399.427 6 ↓

Analogs

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Popular Name: (5S)-1-isopentyl-N-(3-methoxyphenyl)-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-carboxami (5S)-1-isopentyl-N-(3-methoxyphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.40 2.39 -22.06 3 9 0 126 400.435 6 ↓
Ref Reference (pH 7) 1.84 4.26 -40.04 2 9 -1 129 399.427 6 ↓

Analogs

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Popular Name: (5R)-N-(2-chloro-5-methoxy-phenyl)-1-isopentyl-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5 (5R)-N-(2-chloro-5-methoxy-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 3.03 -19.13 3 9 0 126 434.88 6 ↓
Ref Reference (pH 7) 2.48 3.73 -42.8 2 9 -1 129 433.872 6 ↓

Analogs

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Popular Name: (5S)-N-(2-chloro-5-methoxy-phenyl)-1-isopentyl-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5 (5S)-N-(2-chloro-5-methoxy-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 3.03 -19.18 3 9 0 126 434.88 6 ↓
Ref Reference (pH 7) 2.48 4.88 -38.25 2 9 -1 129 433.872 6 ↓

Analogs

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Popular Name: (5R)-N-(2-fluorophenyl)-1-isopentyl-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-carboxamid (5R)-N-(2-fluorophenyl)-1-isopen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.48 3.23 -17.33 3 8 0 117 388.399 5 ↓
Ref Reference (pH 7) 1.93 3.94 -39.49 2 8 -1 119 387.391 5 ↓

Analogs

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Popular Name: (5S)-N-(2-fluorophenyl)-1-isopentyl-2,4,7-trioxo-6,8-dihydro-5H-pyrido[2,3-d]pyrimidine-5-carboxamid (5S)-N-(2-fluorophenyl)-1-isopen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.48 3.2 -17.4 3 8 0 117 388.399 5 ↓
Ref Reference (pH 7) 1.93 5.05 -36.91 2 8 -1 119 387.391 5 ↓

Parameters Provided:

ring.id = 584174
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 584174 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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