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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

38735530
38735530

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Popular Name: (3R)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(3,4-dimethylphenyl)-5-oxo-pyrrolidine-3- (3R)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.54 11.61 -25.63 1 6 0 67 432.549 4 ↓
Lo Low (pH 4.5-6) 3.54 12.05 -41.75 2 6 1 68 433.557 4 ↓

Analogs

38735528
38735528

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Popular Name: (3S)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(3,4-dimethylphenyl)-5-oxo-pyrrolidine-3- (3S)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.54 11.64 -32.09 1 6 0 67 432.549 4 ↓
Lo Low (pH 4.5-6) 3.54 12.08 -44.89 2 6 1 68 433.557 4 ↓

Analogs

38735648
38735648

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Popular Name: (3R)-1-(3-bromophenyl)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-pyrrolidine-3-carbo (3R)-1-(3-bromophenyl)-N-[4-(2,3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.50 11.01 -24.31 1 6 0 67 483.391 4 ↓
Lo Low (pH 4.5-6) 3.50 11.45 -40.22 2 6 1 68 484.399 4 ↓

Analogs

38735646
38735646

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Popular Name: (3S)-1-(3-bromophenyl)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-pyrrolidine-3-carbo (3S)-1-(3-bromophenyl)-N-[4-(2,3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.50 11.04 -30.07 1 6 0 67 483.391 4 ↓
Lo Low (pH 4.5-6) 3.50 11.48 -43.18 2 6 1 68 484.399 4 ↓

Analogs

38735670
38735670
38735902
38735902
38735904
38735904

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Popular Name: (3R)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-1-(p-tolyl)pyrrolidine-3-carboxamide (3R)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 11.05 -25.41 1 6 0 67 418.522 4 ↓
Lo Low (pH 4.5-6) 3.16 11.49 -41.6 2 6 1 68 419.53 4 ↓

Analogs

38735902
38735902
38735904
38735904
38735668
38735668

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Popular Name: (3S)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-1-(p-tolyl)pyrrolidine-3-carboxamide (3S)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 11.1 -31.7 1 6 0 67 418.522 4 ↓
Lo Low (pH 4.5-6) 3.16 11.54 -44.7 2 6 1 68 419.53 4 ↓

Analogs

38735674
38735674

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Popular Name: (3R)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(3-methoxyphenyl)-5-oxo-pyrrolidine-3-car (3R)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 9.67 -28.4 1 7 0 76 434.521 5 ↓
Lo Low (pH 4.5-6) 2.75 10.11 -44.68 2 7 1 78 435.529 5 ↓

Analogs

38735672
38735672

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Popular Name: (3S)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(3-methoxyphenyl)-5-oxo-pyrrolidine-3-car (3S)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 9.71 -35.06 1 7 0 76 434.521 5 ↓
Lo Low (pH 4.5-6) 2.75 10.16 -47.79 2 7 1 78 435.529 5 ↓

Analogs

38735678
38735678

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Popular Name: (3R)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(4-methoxyphenyl)-5-oxo-pyrrolidine-3-car (3R)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 9.67 -26.11 1 7 0 76 434.521 5 ↓
Lo Low (pH 4.5-6) 2.77 10.11 -42.3 2 7 1 78 435.529 5 ↓

Analogs

38735676
38735676

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Popular Name: (3S)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(4-methoxyphenyl)-5-oxo-pyrrolidine-3-car (3S)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 9.71 -32.16 1 7 0 76 434.521 5 ↓
Lo Low (pH 4.5-6) 2.77 10.15 -45.26 2 7 1 78 435.529 5 ↓

Analogs

38735682
38735682

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Popular Name: (3R)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(4-fluorophenyl)-5-oxo-pyrrolidine-3-carb (3R)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 10.46 -24.98 1 6 0 67 422.485 4 ↓
Lo Low (pH 4.5-6) 2.88 10.9 -41.65 2 6 1 68 423.493 4 ↓

Analogs

38735680
38735680

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Popular Name: (3S)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-1-(4-fluorophenyl)-5-oxo-pyrrolidine-3-carb (3S)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.88 10.52 -31.3 1 6 0 67 422.485 4 ↓
Lo Low (pH 4.5-6) 2.88 10.96 -44.55 2 6 1 68 423.493 4 ↓

Analogs

38735686
38735686

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Popular Name: (3R)-1-(4-chlorophenyl)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-pyrrolidine-3-carb (3R)-1-(4-chlorophenyl)-N-[4-(2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.39 10.91 -24.51 1 6 0 67 438.94 4 ↓
Lo Low (pH 4.5-6) 3.39 11.35 -41.04 2 6 1 68 439.948 4 ↓

Analogs

38735684
38735684

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Popular Name: (3S)-1-(4-chlorophenyl)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-pyrrolidine-3-carb (3S)-1-(4-chlorophenyl)-N-[4-(2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.39 10.97 -30.8 1 6 0 67 438.94 4 ↓
Lo Low (pH 4.5-6) 3.39 11.41 -43.98 2 6 1 68 439.948 4 ↓

Analogs

38735904
38735904
38735668
38735668
38735670
38735670

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Popular Name: (3R)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-1-phenyl-pyrrolidine-3-carboxamide (3R)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 10.37 -25.47 1 6 0 67 404.495 4 ↓

Analogs

38735668
38735668
38735670
38735670
38735902
38735902

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-[4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)phenyl]-5-oxo-1-phenyl-pyrrolidine-3-carboxamide (3S)-N-[4-(2,3-dihydroimidazo[2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 10.41 -31.65 1 6 0 67 404.495 4 ↓

Parameters Provided:

ring.id = 599654
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 599654 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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