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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: 2-acetylsulfanyl-N-[4-(3-pyridyl)thiazol-2-yl]-acetamide 2-acetylsulfanyl-N-[4-(3-pyridyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.55 4.87 -11.18 1 5 0 72 293.373 5 ↓
Lo Low (pH 4.5-6) 1.55 5.16 -41.7 2 5 1 73 294.381 5 ↓

Analogs

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Popular Name: 2-methyl-4-(3-pyridyl)thiazole-5-carboxylic 2-methyl-4-(3-pyridyl)thiazole-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.00 4.71 -48.64 0 4 -1 66 219.245 2 ↓

Analogs

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Popular Name: 2-ethyl-4-(3-pyridyl)thiazole-5-carboxylic 2-ethyl-4-(3-pyridyl)thiazole-5-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.48 -48.19 0 4 -1 66 233.272 3 ↓

Analogs

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Popular Name: 1-(3-methoxypropyl)-1-methyl-3-[4-(3-pyridyl)thiazol-2-yl]urea 1-(3-methoxypropyl)-1-methyl-3-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 5.4 -12.71 1 6 0 67 306.391 6 ↓

Analogs

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Popular Name: 2-isopentylsulfanyl-N-[(1S)-1-[4-(3-pyridyl)thiazol-2-yl]ethyl]acetamide 2-isopentylsulfanyl-N-[(1S)-1-[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 7.58 -15.84 1 4 0 55 349.525 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-isopentylsulfanyl-N-[(1R)-1-[4-(3-pyridyl)thiazol-2-yl]ethyl]acetamide 2-isopentylsulfanyl-N-[(1R)-1-[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 7.58 -15.85 1 4 0 55 349.525 8 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-methyl-1-[(1S)-1-methyl-2-methylsulfonyl-ethyl]-3-[4-(3-pyridyl)thiazol-2-yl]urea 1-methyl-1-[(1S)-1-methyl-2-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.08 4.24 -24.55 1 7 0 92 354.457 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-methyl-1-[(1R)-1-methyl-2-methylsulfonyl-ethyl]-3-[4-(3-pyridyl)thiazol-2-yl]urea 1-methyl-1-[(1R)-1-methyl-2-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.08 4.46 -24.04 1 7 0 92 354.457 5 ↓

Analogs

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Popular Name: 1-[(1S)-1,2-dimethylpropyl]-1-ethyl-3-[4-(3-pyridyl)thiazol-2-yl]urea 1-[(1S)-1,2-dimethylpropyl]-1-et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 8.59 -10.08 1 5 0 58 318.446 5 ↓

Analogs

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Popular Name: 1-[(1R)-1,2-dimethylpropyl]-1-ethyl-3-[4-(3-pyridyl)thiazol-2-yl]urea 1-[(1R)-1,2-dimethylpropyl]-1-et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 8.01 -10.39 1 5 0 58 318.446 5 ↓

Analogs

8720929
8720929

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Popular Name: 3-methyl-N-[4-(3-pyridyl)thiazol-2-yl]butanamide 3-methyl-N-[4-(3-pyridyl)thiazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 5.87 -10.13 1 4 0 55 261.35 4 ↓

Analogs

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Popular Name: 5-oxo-5-[[4-(3-pyridyl)thiazol-2-yl]amino]pentanoic 5-oxo-5-[[4-(3-pyridyl)thiazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 6 -54.36 1 6 -1 95 290.324 6 ↓

Analogs

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Popular Name: 4-oxo-4-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}butanoic acid 4-oxo-4-{[4-(pyridin-3-yl)-1,3-t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.56 5.21 -45.82 1 6 -1 95 276.297 5 ↓
Lo Low (pH 4.5-6) 0.56 3.24 -12.14 2 6 0 92 277.305 5 ↓

Analogs

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Popular Name: 2-methoxy-N-[4-(3-pyridyl)thiazol-2-yl]acetamide 2-methoxy-N-[4-(3-pyridyl)thiazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.76 3.82 -13.24 1 5 0 64 249.295 4 ↓
Hi High (pH 8-9.5) 0.94 1.24 -42.06 0 5 -1 70 248.287 4 ↓

Analogs

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Popular Name: 1,1-dimethyl-3-[4-(3-pyridyl)thiazol-2-yl]urea 1,1-dimethyl-3-[4-(3-pyridyl)thi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.96 4.56 -11.17 1 5 0 58 248.311 2 ↓

Analogs

813405
813405

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Popular Name: 5-methyl-4-(3-pyridyl)thiazol-2-amine 5-methyl-4-(3-pyridyl)thiazol-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.30 3.35 -8.55 2 3 0 52 191.259 1 ↓
Lo Low (pH 4.5-6) 1.30 3.73 -29.6 3 3 1 53 192.267 1 ↓

Analogs

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Popular Name: 2-[5-isopropyl-4-(3-pyridyl)thiazol-2-yl]ethanamine 2-[5-isopropyl-4-(3-pyridyl)thia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 4.22 -50.27 3 3 1 53 248.375 4 ↓

Analogs

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Popular Name: 2-(diethylamino)-N-[4-(3-pyridyl)thiazol-2-yl]acetamide 2-(diethylamino)-N-[4-(3-pyridyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.92 6.59 -44.5 2 5 1 59 291.4 6 ↓
Hi High (pH 8-9.5) 1.92 4.59 -10.69 1 5 0 58 290.392 6 ↓

Parameters Provided:

ring.id = 6209
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 6209 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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