UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 2-acetylsulfanyl-N-[4-(2-pyridyl)thiazol-2-yl]-acetamide 2-acetylsulfanyl-N-[4-(2-pyridyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.48 5.06 -11.37 1 5 0 72 293.373 5 ↓
Lo Low (pH 4.5-6) 1.48 5.32 -38.02 2 5 1 73 294.381 5 ↓

Analogs

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Popular Name: 1-isopropyl-3-[4-(2-pyridyl)thiazol-2-yl]urea 1-isopropyl-3-[4-(2-pyridyl)thia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 4.17 -14.17 2 5 0 67 262.338 3 ↓

Analogs

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Popular Name: 2-Bromo-4-(pyridin-2-yl)thiazole 2-Bromo-4-(pyridin-2-yl)thiazole

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 4.21 -5.8 0 2 0 26 241.113 1 ↓

Analogs

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Popular Name: 1-(2-bromoallyl)-3-[4-(2-pyridyl)thiazol-2-yl]urea 1-(2-bromoallyl)-3-[4-(2-pyridyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 4.55 -10.26 2 5 0 67 339.218 4 ↓

Analogs

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Popular Name: (2S)-2-allyloxy-N-[4-(2-pyridyl)thiazol-2-yl]propanamide (2S)-2-allyloxy-N-[4-(2-pyridyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 6.23 -13.33 1 5 0 64 289.36 6 ↓

Analogs

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Popular Name: (2R)-2-allyloxy-N-[4-(2-pyridyl)thiazol-2-yl]propanamide (2R)-2-allyloxy-N-[4-(2-pyridyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 6.23 -13.22 1 5 0 64 289.36 6 ↓

Analogs

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Popular Name: N-methyl-2-[4-(2-pyridyl)thiazol-2-yl]ethanamine N-methyl-2-[4-(2-pyridyl)thiazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.09 4.37 -45.72 2 3 1 42 220.321 4 ↓

Analogs

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Popular Name: 2-[isopropyl(methyl)amino]-N-[4-(2-pyridyl)thiazol-2-yl]acetamide 2-[isopropyl(methyl)amino]-N-[4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 6.63 -43.99 2 5 1 59 291.4 5 ↓
Hi High (pH 8-9.5) 1.77 4.19 -10.86 1 5 0 58 290.392 5 ↓
Mid Mid (pH 6-8) 1.59 5.79 -35.96 1 5 0 66 290.392 5 ↓

Analogs

813401
813401

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Popular Name: 5-methyl-4-(2-pyridyl)thiazol-2-amine 5-methyl-4-(2-pyridyl)thiazol-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.22 3.97 -8.03 2 3 0 52 191.259 1 ↓

Analogs

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Popular Name: 2-[5-isopropyl-4-(2-pyridyl)thiazol-2-yl]ethanamine 2-[5-isopropyl-4-(2-pyridyl)thia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.39 5.02 -50.1 3 3 1 53 248.375 4 ↓

Parameters Provided:

ring.id = 6210
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 6210 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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