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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: 6-(methylamino)-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 6-(methylamino)-N-(1-methyl-4-pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.55 1.64 -44.46 3 6 1 76 285.393 4 ↓
Hi High (pH 8-9.5) 0.55 -0.76 -9.53 2 6 0 74 284.385 4 ↓

Analogs

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Popular Name: 6-(ethylamino)-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 6-(ethylamino)-N-(1-methyl-4-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 2.51 -43.83 3 6 1 76 299.42 5 ↓
Hi High (pH 8-9.5) 0.93 0.11 -9.27 2 6 0 74 298.412 5 ↓

Analogs

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Popular Name: N-(1-methyl-4-piperidyl)-6-(propylamino)pyridine-3-sulfonamide N-(1-methyl-4-piperidyl)-6-(prop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.43 3.28 -43.72 3 6 1 76 313.447 6 ↓
Hi High (pH 8-9.5) 1.43 0.88 -9.03 2 6 0 74 312.439 6 ↓

Analogs

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Popular Name: 2-(methylamino)-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 2-(methylamino)-N-(1-methyl-4-pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.34 2.52 -45.08 3 6 1 76 285.393 4 ↓
Hi High (pH 8-9.5) 0.34 0.12 -9.49 2 6 0 74 284.385 4 ↓

Analogs

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Popular Name: 2-(ethylamino)-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 2-(ethylamino)-N-(1-methyl-4-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.71 3.2 -44.89 3 6 1 76 299.42 5 ↓
Hi High (pH 8-9.5) 0.71 0.79 -9.07 2 6 0 74 298.412 5 ↓

Analogs

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Popular Name: N-(1-methyl-4-piperidyl)-2-(propylamino)pyridine-3-sulfonamide N-(1-methyl-4-piperidyl)-2-(prop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.21 3.96 -44.82 3 6 1 76 313.447 6 ↓
Hi High (pH 8-9.5) 1.21 1.54 -8.93 2 6 0 74 312.439 6 ↓

Analogs

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Popular Name: 5-bromo-2-(methylamino)-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 5-bromo-2-(methylamino)-N-(1-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.29 3.12 -44.39 3 6 1 76 364.289 4 ↓
Hi High (pH 8-9.5) 1.29 0.72 -8.04 2 6 0 74 363.281 4 ↓

Analogs

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Popular Name: 5-bromo-2-(ethylamino)-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 5-bromo-2-(ethylamino)-N-(1-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.67 3.8 -44.16 3 6 1 76 378.316 5 ↓
Hi High (pH 8-9.5) 1.67 1.39 -7.51 2 6 0 74 377.308 5 ↓

Analogs

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Popular Name: 6-amino-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 6-amino-N-(1-methyl-4-piperidyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.18 0.75 -46.59 4 6 1 90 271.366 3 ↓
Hi High (pH 8-9.5) 0.18 -1.64 -9.86 3 6 0 88 270.358 3 ↓

Analogs

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Popular Name: 2-amino-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 2-amino-N-(1-methyl-4-piperidyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.04 1.31 -45.04 4 6 1 90 271.366 3 ↓
Hi High (pH 8-9.5) -0.04 -1.08 -9.4 3 6 0 88 270.358 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-amino-5-bromo-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 2-amino-5-bromo-N-(1-methyl-4-pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.92 1.9 -44.41 4 6 1 90 350.262 3 ↓
Hi High (pH 8-9.5) 0.92 -0.49 -8.06 3 6 0 88 349.254 3 ↓

Analogs

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Popular Name: N-(1-butyl-4-piperidyl)-5-fluoro-pyridine-3-sulfonamide N-(1-butyl-4-piperidyl)-5-fluoro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 4.26 -45.59 2 5 1 63 316.422 6 ↓
Hi High (pH 8-9.5) 2.10 2.04 -7.49 1 5 0 62 315.414 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-amino-N-(1-methylsulfonyl-4-piperidyl)pyridine-3-sulfonamide 6-amino-N-(1-methylsulfonyl-4-pi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.45 -2.65 -19.21 3 8 0 122 334.423 4 ↓

Analogs

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Popular Name: 6-nitro-N-(4-piperidyl)pyridine-3-sulfonamide 6-nitro-N-(4-piperidyl)pyridine-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.06 1.45 -54.54 3 8 1 121 287.321 4 ↓
Hi High (pH 8-9.5) 0.06 1.41 -45.37 2 8 0 124 286.313 4 ↓

Analogs

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Popular Name: N-methyl-6-nitro-N-(4-piperidyl)pyridine-3-sulfonamide N-methyl-6-nitro-N-(4-piperidyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.30 3.3 -54.58 2 8 1 113 301.348 4 ↓

Analogs

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Popular Name: N-ethyl-6-nitro-N-(4-piperidyl)pyridine-3-sulfonamide N-ethyl-6-nitro-N-(4-piperidyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.68 3.95 -55.22 2 8 1 113 315.375 5 ↓

Analogs

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Popular Name: 6-amino-N-(1-isopropyl-4-piperidyl)-N-methyl-pyridine-3-sulfonamide 6-amino-N-(1-isopropyl-4-piperid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 3.7 -43.62 3 6 1 81 313.447 4 ↓
Hi High (pH 8-9.5) 1.10 1.52 -9.41 2 6 0 80 312.439 4 ↓

Analogs

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Popular Name: 6-amino-N-(2-hydroxyethyl)-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 6-amino-N-(2-hydroxyethyl)-N-(1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.21 1.03 -50.62 4 7 1 101 315.419 5 ↓
Hi High (pH 8-9.5) -0.21 -1.36 -12.34 3 7 0 100 314.411 5 ↓

Analogs

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Popular Name: 2-[4-[(6-amino-3-pyridyl)sulfonylamino]-1-piperidyl]acetamide 2-[4-[(6-amino-3-pyridyl)sulfony…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.09 -2.31 -49.03 6 8 1 133 314.391 5 ↓
Mid Mid (pH 6-8) -1.09 -4.51 -15.66 5 8 0 131 313.383 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-amino-N-(1-ethyl-4-piperidyl)pyridine-3-sulfonamide 6-amino-N-(1-ethyl-4-piperidyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.56 1.41 -45.56 4 6 1 90 285.393 4 ↓
Hi High (pH 8-9.5) 0.56 -0.84 -9.72 3 6 0 88 284.385 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-amino-N-methyl-N-(1-propyl-4-piperidyl)pyridine-3-sulfonamide 6-amino-N-methyl-N-(1-propyl-4-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.30 3.92 -45.91 3 6 1 81 313.447 5 ↓
Hi High (pH 8-9.5) 1.30 1.71 -9.38 2 6 0 80 312.439 5 ↓

Analogs

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Popular Name: 6-amino-N-(1-tert-butyl-4-piperidyl)pyridine-3-sulfonamide 6-amino-N-(1-tert-butyl-4-piperi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 2.15 -43 4 6 1 90 313.447 4 ↓
Hi High (pH 8-9.5) 1.36 0.02 -9.53 3 6 0 88 312.439 4 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 0.84 -14.99 1 7 0 89 299.352 4 ↓

Analogs

37982274
37982274

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Popular Name: 6-chloro-N-(1-methyl-4-piperidyl)pyridine-3-sulfonamide 6-chloro-N-(1-methyl-4-piperidyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.37 2.43 -47.45 2 5 1 63 290.796 3 ↓
Hi High (pH 8-9.5) 1.37 2.34 -42.27 1 5 0 66 289.788 3 ↓

Analogs

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Popular Name: 6-hydrazino-N-(1-propyl-4-piperidyl)pyridine-3-sulfonamide 6-hydrazino-N-(1-propyl-4-piperi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.82 2.06 -48 5 7 1 102 314.435 6 ↓

Analogs

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Popular Name: 2-hydrazino-N-(1-propyl-4-piperidyl)pyridine-3-sulfonamide 2-hydrazino-N-(1-propyl-4-piperi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 2.55 -46.57 5 7 1 102 314.435 6 ↓

Parameters Provided:

ring.id = 6266
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 6266 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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