ZINC 12

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ZINC Item

Suppliers, Protomers, & Similar Substances

8980426

Analogs

8980429
8980431
12648065
12648068
12648073

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(2,4-difluorophenyl)ethyl]-2-(4-methyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl)-acetamide N-[1-(2,4-difluorophenyl)ethyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	0.09	-15.91	2	6	0	78	387.386	5	↓ MOL2 SDF SMILES Flexibase

8980429

Analogs

8980431
12648065
12648068
12648073
12648077

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(2,4-difluorophenyl)ethyl]-2-(4-methyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl)-acetamide N-[1-(2,4-difluorophenyl)ethyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	0.09	-15.89	2	6	0	78	387.386	5	↓ MOL2 SDF SMILES Flexibase

8980431

Analogs

12648065
12648068
12648073
12648077
12693623

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(2,4-difluorophenyl)ethyl]-2-(4-methyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl)-acetamide N-[1-(2,4-difluorophenyl)ethyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	0.09	-17.14	2	6	0	78	387.386	5	↓ MOL2 SDF SMILES Flexibase

8980479

Analogs

8980483
8980485
8980489
8644064
8644067

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(2-chlorophenyl)ethyl]-2-[4-methyl-2,5-dioxo-4-(4-tert-butylphenyl)-imidazolidin-1-yl]-acetamid N-[1-(2-chlorophenyl)ethyl]-2-[4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.11	-0.3	-16.4	2	6	0	78	441.959	6	↓ MOL2 SDF SMILES Flexibase

8980483

Analogs

8980485
8980489
8980479
8644064
8644067

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(2-chlorophenyl)ethyl]-2-[4-methyl-2,5-dioxo-4-(4-tert-butylphenyl)-imidazolidin-1-yl]-acetamid N-[1-(2-chlorophenyl)ethyl]-2-[4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.11	-0.3	-16.33	2	6	0	78	441.959	6	↓ MOL2 SDF SMILES Flexibase

8980485

Analogs

8980489
8980479
8980483
8644064

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(2-chlorophenyl)ethyl]-2-[4-methyl-2,5-dioxo-4-(4-tert-butylphenyl)-imidazolidin-1-yl]-acetamid N-[1-(2-chlorophenyl)ethyl]-2-[4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.11	-0.34	-16.48	2	6	0	78	441.959	6	↓ MOL2 SDF SMILES Flexibase

8980489

Analogs

8980479
8980483
8980485

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(2-chlorophenyl)ethyl]-2-[4-methyl-2,5-dioxo-4-(4-tert-butylphenyl)-imidazolidin-1-yl]-acetamid N-[1-(2-chlorophenyl)ethyl]-2-[4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.11	-0.35	-16.46	2	6	0	78	441.959	6	↓ MOL2 SDF SMILES Flexibase

17970172

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]-N-[(1S)-1-(2-methoxyphenyl)ethyl]acetamide 2-[(4S)-4-ethyl-2,5-dioxo-4-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	7.62	-16.09	2	7	0	88	395.459	7	↓ MOL2 SDF SMILES Flexibase

17970175

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]-N-[(1S)-1-(2-methoxyphenyl)ethyl]acetamide 2-[(4R)-4-ethyl-2,5-dioxo-4-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	7.68	-17.3	2	7	0	88	395.459	7	↓ MOL2 SDF SMILES Flexibase

17970179

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]-N-[(1R)-1-(2-methoxyphenyl)ethyl]acetamide 2-[(4S)-4-ethyl-2,5-dioxo-4-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	7.78	-17.19	2	7	0	88	395.459	7	↓ MOL2 SDF SMILES Flexibase

17970184

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]-N-[(1R)-1-(2-methoxyphenyl)ethyl]acetamide 2-[(4R)-4-ethyl-2,5-dioxo-4-phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.28	7.66	-15.88	2	7	0	88	395.459	7	↓ MOL2 SDF SMILES Flexibase

36640970

Analogs

36640972

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acet 2-[(4S)-4-(2,4-dichlorophenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	6.72	-14.38	2	7	0	88	436.295	6	↓ MOL2 SDF SMILES Flexibase

36640972

Analogs

36640970

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acet 2-[(4R)-4-(2,4-dichlorophenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	6.72	-14.28	2	7	0	88	436.295	6	↓ MOL2 SDF SMILES Flexibase

36640996

Analogs

36640998
3464444

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-4-(4-chlorophenyl)-4-ethyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acetamide 2-[(4S)-4-(4-chlorophenyl)-4-eth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.42	7.24	-14.95	2	7	0	88	415.877	7	↓ MOL2 SDF SMILES Flexibase

36640998

Analogs

36640996
3464444

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-4-(4-chlorophenyl)-4-ethyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acetamide 2-[(4R)-4-(4-chlorophenyl)-4-eth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.42	7.14	-14.12	2	7	0	88	415.877	7	↓ MOL2 SDF SMILES Flexibase

36641021

Analogs

36641024
36888414
36888416
4475867
4475869

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-4-(4-tert-butylphenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acet 2-[(4S)-4-(4-tert-butylphenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	7.96	-15.16	2	7	0	88	423.513	7	↓ MOL2 SDF SMILES Flexibase

36641024

Analogs

36888414
36888416
36641021
4475867
4475869

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-4-(4-tert-butylphenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acet 2-[(4R)-4-(4-tert-butylphenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	7.96	-13.99	2	7	0	88	423.513	7	↓ MOL2 SDF SMILES Flexibase

13012955

Analogs

13012956

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[2-(diethylaminomethyl)phenyl]methyl]-2-[(4S)-4-(4-fluorophenyl)-4-methyl-2,5-dioxo-imidazolidin- N-[[2-(diethylaminomethyl)phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.88	9.65	-41.55	3	7	1	83	441.527	9	↓ MOL2 SDF SMILES Flexibase

13012956

Analogs

13012955

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[2-(diethylaminomethyl)phenyl]methyl]-2-[(4R)-4-(4-fluorophenyl)-4-methyl-2,5-dioxo-imidazolidin- N-[[2-(diethylaminomethyl)phenyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.88	9.66	-41.31	3	7	1	83	441.527	9	↓ MOL2 SDF SMILES Flexibase

22741568

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2-chlorophenyl)methyl]-2-[(4S)-4-isobutyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-[(2-chlorophenyl)methyl]-2-[(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.12	9.72	-16.25	2	6	0	79	413.905	7	↓ MOL2 SDF SMILES Flexibase

22741571

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2-chlorophenyl)methyl]-2-[(4R)-4-isobutyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-[(2-chlorophenyl)methyl]-2-[(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.12	9.14	-16.27	2	6	0	79	413.905	7	↓ MOL2 SDF SMILES Flexibase

22741630

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-N-tert-butyl-2-[(4S)-4-isobutyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-benzyl-N-tert-butyl-2-[(4S)-4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.42	12.6	-16.03	1	6	0	70	435.568	8	↓ MOL2 SDF SMILES Flexibase

22741634

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-N-tert-butyl-2-[(4R)-4-isobutyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-benzyl-N-tert-butyl-2-[(4R)-4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.42	11.84	-16.11	1	6	0	70	435.568	8	↓ MOL2 SDF SMILES Flexibase

22745069

Analogs

31069000
31069002
8889878
8889880
7277074

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4S)-4-(4-methoxyphenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-propyl-acetamide N-benzyl-2-[(4S)-4-(4-methoxyphe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.89	9.35	-18.19	1	7	0	79	409.486	8	↓ MOL2 SDF SMILES Flexibase

22745073

Analogs

31069000
31069002
14267762
14267763
8889878

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4R)-4-(4-methoxyphenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-propyl-acetamide N-benzyl-2-[(4R)-4-(4-methoxyphe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.89	9.36	-18.09	1	7	0	79	409.486	8	↓ MOL2 SDF SMILES Flexibase

36875650

Analogs

36875651

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(4-chlorophenyl)methyl]-2-[(4S)-4-methyl-4-(4-nitrophenyl)-2,5-dioxo-imidazolidin-1-yl]acetamide N-[(4-chlorophenyl)methyl]-2-[(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.85	7.58	-17.31	2	9	0	124	416.821	6	↓ MOL2 SDF SMILES Flexibase

36875651

Analogs

36875650

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(4-chlorophenyl)methyl]-2-[(4R)-4-methyl-4-(4-nitrophenyl)-2,5-dioxo-imidazolidin-1-yl]acetamide N-[(4-chlorophenyl)methyl]-2-[(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.85	7.58	-16.4	2	9	0	124	416.821	6	↓ MOL2 SDF SMILES Flexibase

36875984

Analogs

36875985
23261879
23261883
3595125

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4R)-4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-ethyl-acetamide N-benzyl-2-[(4R)-4-(2,4-dichloro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.61	10.39	-14.5	1	6	0	70	434.323	6	↓ MOL2 SDF SMILES Flexibase

36875985

Analogs

36875984
23261879
23261883

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4S)-4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-ethyl-acetamide N-benzyl-2-[(4S)-4-(2,4-dichloro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.61	10.4	-14.28	1	6	0	70	434.323	6	↓ MOL2 SDF SMILES Flexibase

36876120

Analogs

36876121
3595345
3595346

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4S)-4-(4-chlorophenyl)-4-ethyl-2,5-dioxo-imidazolidin-1-yl]-N-ethyl-acetamide N-benzyl-2-[(4S)-4-(4-chlorophen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	10.92	-15.16	1	6	0	70	413.905	7	↓ MOL2 SDF SMILES Flexibase

36876121

Analogs

3595345
3595346
36876120

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4R)-4-(4-chlorophenyl)-4-ethyl-2,5-dioxo-imidazolidin-1-yl]-N-ethyl-acetamide N-benzyl-2-[(4R)-4-(4-chlorophen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.51	10.82	-13.96	1	6	0	70	413.905	7	↓ MOL2 SDF SMILES Flexibase

23043132

Analogs

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Popular Name: N-benzyl-2-[(4S)-4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-(2,2,2-trifluoroethy N-benzyl-2-[(4S)-4-(2,4-dichloro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.16	10.65	-17.12	1	6	0	70	488.293	7	↓ MOL2 SDF SMILES Flexibase

23043134

Analogs

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Popular Name: N-benzyl-2-[(4R)-4-(2,4-dichlorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-(2,2,2-trifluoroethy N-benzyl-2-[(4R)-4-(2,4-dichloro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.16	10.63	-17.27	1	6	0	70	488.293	7	↓ MOL2 SDF SMILES Flexibase

59013077

Analogs

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Popular Name: 2-[(4R)-4-(2,4-difluorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(1S)-3-methyl-1-phenyl-butyl 2-[(4R)-4-(2,4-difluorophenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.40	9.34	-13.19	2	6	0	79	429.467	7	↓ MOL2 SDF SMILES Flexibase

59013078

Analogs

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Popular Name: 2-[(4R)-4-(2,4-difluorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(1R)-3-methyl-1-phenyl-butyl 2-[(4R)-4-(2,4-difluorophenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.40	9.35	-14.46	2	6	0	79	429.467	7	↓ MOL2 SDF SMILES Flexibase

59013080

Analogs

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Popular Name: 2-[(4S)-4-(2,4-difluorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(1S)-3-methyl-1-phenyl-butyl 2-[(4S)-4-(2,4-difluorophenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.40	9.35	-13.03	2	6	0	79	429.467	7	↓ MOL2 SDF SMILES Flexibase

59013082

Analogs

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Popular Name: 2-[(4S)-4-(2,4-difluorophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(1R)-3-methyl-1-phenyl-butyl 2-[(4S)-4-(2,4-difluorophenyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.40	9.36	-14.4	2	6	0	79	429.467	7	↓ MOL2 SDF SMILES Flexibase

14227540

Analogs

14227543
14227546
14227549

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Popular Name: N-[(1S)-1-(3,4-difluorophenyl)ethyl]-2-[(4S)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-[(1S)-1-(3,4-difluorophenyl)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	8.48	-15.9	2	6	0	79	401.413	6	↓ MOL2 SDF SMILES Flexibase

14227543

Analogs

14227546
14227549
14227540

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-1-(3,4-difluorophenyl)ethyl]-2-[(4R)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-[(1S)-1-(3,4-difluorophenyl)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	8.39	-15.23	2	6	0	79	401.413	6	↓ MOL2 SDF SMILES Flexibase

14227546

Analogs

14227549
14227540
14227543

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(3,4-difluorophenyl)ethyl]-2-[(4S)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-[(1R)-1-(3,4-difluorophenyl)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	8.49	-17.01	2	6	0	79	401.413	6	↓ MOL2 SDF SMILES Flexibase

14227549

Analogs

14227540
14227543

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(3,4-difluorophenyl)ethyl]-2-[(4R)-4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl]acetamide N-[(1R)-1-(3,4-difluorophenyl)et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.53	8.39	-16.88	2	6	0	79	401.413	6	↓ MOL2 SDF SMILES Flexibase

14249516

Analogs

43744656
43744657
43744658
43744659
3314428

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Popular Name: N-benzyl-2-[(4S)-4-ethyl-2,5-dioxo-4-(p-tolyl)imidazolidin-1-yl]acetamide N-benzyl-2-[(4S)-4-ethyl-2,5-dio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.16	8.21	-13.89	2	6	0	79	365.433	6	↓ MOL2 SDF SMILES Flexibase

14249518

Analogs

43744656
43744657
43744658
43744659
3314428

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4R)-4-ethyl-2,5-dioxo-4-(p-tolyl)imidazolidin-1-yl]acetamide N-benzyl-2-[(4R)-4-ethyl-2,5-dio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.16	8.09	-12.65	2	6	0	79	365.433	6	↓ MOL2 SDF SMILES Flexibase

14251404

Analogs

14251406

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Popular Name: 2-[(4S)-4-(2-bromophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acetamide 2-[(4S)-4-(2-bromophenyl)-4-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.00	6.05	-16.28	2	7	0	88	446.301	6	↓ MOL2 SDF SMILES Flexibase

14251406

Analogs

14251404

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-4-(2-bromophenyl)-4-methyl-2,5-dioxo-imidazolidin-1-yl]-N-[(3-methoxyphenyl)methyl]acetamide 2-[(4R)-4-(2-bromophenyl)-4-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.00	6.28	-14.82	2	7	0	88	446.301	6	↓ MOL2 SDF SMILES Flexibase

3593092

Analogs

39544655
39544657

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4R)-4-(3-bromophenyl)-2,5-diketo-4-methyl-imidazolidin-1-yl]-N-veratryl-acetamide 2-[(4R)-4-(3-bromophenyl)-2,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.64	-2.61	-15.84	2	8	0	96	476.327	7	↓ MOL2 SDF SMILES Flexibase

3593095

Analogs

39544655
39544657

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-4-(3-bromophenyl)-2,5-diketo-4-methyl-imidazolidin-1-yl]-N-veratryl-acetamide 2-[(4S)-4-(3-bromophenyl)-2,5-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.64	-2.56	-17.25	2	8	0	96	476.327	7	↓ MOL2 SDF SMILES Flexibase

3593151

Analogs

39544655
39544657

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Popular Name: N-benzyl-2-[(4S)-4-(3-bromophenyl)-2,5-diketo-4-methyl-imidazolidin-1-yl]-N-isopropyl-acetamide N-benzyl-2-[(4S)-4-(3-bromopheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.41	-0.42	-14.92	1	6	0	69	458.356	6	↓ MOL2 SDF SMILES Flexibase

3593153

Analogs

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Popular Name: N-benzyl-2-[(4R)-4-(3-bromophenyl)-2,5-diketo-4-methyl-imidazolidin-1-yl]-N-isopropyl-acetamide N-benzyl-2-[(4R)-4-(3-bromopheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.41	-0.45	-14.32	1	6	0	69	458.356	6	↓ MOL2 SDF SMILES Flexibase

3593264

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-benzyl-2-[(4R)-4-(3-bromophenyl)-2,5-diketo-4-methyl-imidazolidin-1-yl]-N-methyl-acetamide N-benzyl-2-[(4R)-4-(3-bromopheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.74	-0.91	-14.6	1	6	0	69	430.302	5	↓ MOL2 SDF SMILES Flexibase

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