UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 2-(phenoxymethyl)-1-[(2,3,5,6-tetramethylphenyl)methyl]benzimidazole 2-(phenoxymethyl)-1-[(2,3,5,6-te…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.43 13.47 -12.01 0 3 0 27 370.496 5 ↓
Lo Low (pH 4.5-6) 6.43 13.92 -27.43 1 3 1 28 371.504 5 ↓

Analogs

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Popular Name: 2-(phenoxymethyl)-1-[(2,4,6-trimethylphenyl)methyl]benzimidazole 2-(phenoxymethyl)-1-[(2,4,6-trim…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.05 12.8 -12.51 0 3 0 27 356.469 5 ↓
Lo Low (pH 4.5-6) 6.05 13.51 -26.88 1 3 1 28 357.477 5 ↓

Analogs

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Popular Name: 1-[(3-bromophenyl)methyl]-2-(phenoxymethyl)benzimidazole 1-[(3-bromophenyl)methyl]-2-(phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.63 12.49 -10.96 0 3 0 27 393.284 5 ↓
Lo Low (pH 4.5-6) 5.63 13.21 -32.69 1 3 1 28 394.292 5 ↓

Analogs

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Popular Name: 1-[(4-bromophenyl)methyl]-2-(phenoxymethyl)benzimidazole 1-[(4-bromophenyl)methyl]-2-(phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.66 12.5 -11.05 0 3 0 27 393.284 5 ↓
Lo Low (pH 4.5-6) 5.66 13.22 -33.34 1 3 1 28 394.292 5 ↓

Analogs

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Popular Name: 1-[(4-methoxyphenyl)methyl]-2-(phenoxymethyl)benzimidazole 1-[(4-methoxyphenyl)methyl]-2-(p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.91 11.18 -12.13 0 4 0 36 344.414 6 ↓
Lo Low (pH 4.5-6) 4.91 11.89 -32.1 1 4 1 38 345.422 6 ↓

Analogs

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Popular Name: 2-[(4-chlorophenoxy)methyl]-1-[(2,5-dimethylphenyl)methyl]benzimidazole 2-[(4-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.35 13.23 -9.99 0 3 0 27 376.887 5 ↓
Lo Low (pH 4.5-6) 6.35 13.93 -31.74 1 3 1 28 377.895 5 ↓

Analogs

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Popular Name: 2-[(4-chlorophenoxy)methyl]-1-[(2,3,5,6-tetramethylphenyl)methyl]benzimidazole 2-[(4-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.11 13.98 -11.02 0 3 0 27 404.941 5 ↓
Lo Low (pH 4.5-6) 7.11 14.44 -30.04 1 3 1 28 405.949 5 ↓

Analogs

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Popular Name: 2-[(4-chlorophenoxy)methyl]-1-[(2,4,6-trimethylphenyl)methyl]benzimidazole 2-[(4-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.73 13.31 -11.6 0 3 0 27 390.914 5 ↓
Lo Low (pH 4.5-6) 6.73 14.02 -29.24 1 3 1 28 391.922 5 ↓

Analogs

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Popular Name: 1-[(2-chloro-6-fluoro-phenyl)methyl]-2-[(4-chlorophenoxy)methyl]benzimidazole 1-[(2-chloro-6-fluoro-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.27 12.5 -9.53 0 3 0 27 401.268 5 ↓
Lo Low (pH 4.5-6) 6.27 13.08 -25.89 1 3 1 28 402.276 5 ↓

Analogs

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Popular Name: 1-[(3-bromophenyl)methyl]-2-[(4-chlorophenoxy)methyl]benzimidazole 1-[(3-bromophenyl)methyl]-2-[(4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.31 13.01 -10.27 0 3 0 27 427.729 5 ↓
Lo Low (pH 4.5-6) 6.31 13.73 -33.75 1 3 1 28 428.737 5 ↓

Analogs

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Popular Name: 1-[(4-bromophenyl)methyl]-2-[(4-chlorophenoxy)methyl]benzimidazole 1-[(4-bromophenyl)methyl]-2-[(4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.34 13.02 -10.7 0 3 0 27 427.729 5 ↓
Lo Low (pH 4.5-6) 6.34 13.73 -36.65 1 3 1 28 428.737 5 ↓

Analogs

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Popular Name: 2-[(4-chlorophenoxy)methyl]-1-[(4-methoxyphenyl)methyl]benzimidazole 2-[(4-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.58 11.7 -11.68 0 4 0 36 378.859 6 ↓
Lo Low (pH 4.5-6) 5.58 12.4 -35.24 1 4 1 38 379.867 6 ↓

Analogs

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Popular Name: 2-[(4-chlorophenoxy)methyl]-1-[(2-methoxyphenyl)methyl]benzimidazole 2-[(4-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.54 11.95 -11.16 0 4 0 36 378.859 6 ↓
Lo Low (pH 4.5-6) 5.54 12.65 -31.72 1 4 1 38 379.867 6 ↓

Analogs

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Popular Name: 2-[(2,4-dichlorophenoxy)methyl]-1-[(2,5-dimethylphenyl)methyl]benzimidazole 2-[(2,4-dichlorophenoxy)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.96 13.78 -10.98 0 3 0 27 411.332 5 ↓
Lo Low (pH 4.5-6) 6.96 14.48 -33.11 1 3 1 28 412.34 5 ↓

Analogs

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Popular Name: 2-[(2,4-dichlorophenoxy)methyl]-1-[(2,3,5,6-tetramethylphenyl)methyl]benzimidazole 2-[(2,4-dichlorophenoxy)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.71 14.53 -12.53 0 3 0 27 439.386 5 ↓
Lo Low (pH 4.5-6) 7.71 14.99 -30.98 1 3 1 28 440.394 5 ↓

Analogs

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Popular Name: 2-[(2,4-dichlorophenoxy)methyl]-1-[(2,4,6-trimethylphenyl)methyl]benzimidazole 2-[(2,4-dichlorophenoxy)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.33 13.86 -12.87 0 3 0 27 425.359 5 ↓
Lo Low (pH 4.5-6) 7.33 14.57 -29.99 1 3 1 28 426.367 5 ↓

Analogs

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Popular Name: 1-[(3-bromophenyl)methyl]-2-[(2,4-dichlorophenoxy)methyl]benzimidazole 1-[(3-bromophenyl)methyl]-2-[(2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.92 13.56 -10.92 0 3 0 27 462.174 5 ↓
Lo Low (pH 4.5-6) 6.92 14.28 -34.94 1 3 1 28 463.182 5 ↓

Analogs

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Popular Name: 1-[(4-bromophenyl)methyl]-2-[(2,4-dichlorophenoxy)methyl]benzimidazole 1-[(4-bromophenyl)methyl]-2-[(2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.94 13.57 -11.73 0 3 0 27 462.174 5 ↓
Lo Low (pH 4.5-6) 6.94 14.28 -38.27 1 3 1 28 463.182 5 ↓

Analogs

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Popular Name: 2-[(2,4-dichlorophenoxy)methyl]-1-[(4-methoxyphenyl)methyl]benzimidazole 2-[(2,4-dichlorophenoxy)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.19 12.25 -12.53 0 4 0 36 413.304 6 ↓
Lo Low (pH 4.5-6) 6.19 12.95 -36.69 1 4 1 38 414.312 6 ↓

Analogs

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Popular Name: 2-[(2,4-dichlorophenoxy)methyl]-1-[[4-[(1R)-1-methylpropyl]phenyl]methyl]benzimidazole 2-[(2,4-dichlorophenoxy)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.99 15.54 -10.75 0 3 0 27 439.386 7 ↓
Lo Low (pH 4.5-6) 7.99 16.25 -33.81 1 3 1 28 440.394 7 ↓

Analogs

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Popular Name: 2-[(2,4-dichlorophenoxy)methyl]-1-[[4-[(1S)-1-methylpropyl]phenyl]methyl]benzimidazole 2-[(2,4-dichlorophenoxy)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.99 15.54 -10.73 0 3 0 27 439.386 7 ↓
Lo Low (pH 4.5-6) 7.99 16.25 -33.8 1 3 1 28 440.394 7 ↓

Analogs

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Popular Name: 2-[(2,4-dichlorophenoxy)methyl]-1-[(2-methoxyphenyl)methyl]benzimidazole 2-[(2,4-dichlorophenoxy)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.14 12.5 -12.3 0 4 0 36 413.304 6 ↓
Lo Low (pH 4.5-6) 6.14 13.2 -33.24 1 4 1 38 414.312 6 ↓

Analogs

39908562
39908562

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Popular Name: 1-benzyl-2-[(2-chlorophenoxy)methyl]benzimidazole 1-benzyl-2-[(2-chlorophenoxy)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.48 12.44 -12.07 0 3 0 27 348.833 5 ↓
Lo Low (pH 4.5-6) 5.48 13.14 -31.14 1 3 1 28 349.841 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(1S)-1-phenylethyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.84 12.78 -11.71 0 3 0 27 362.86 5 ↓
Lo Low (pH 4.5-6) 5.84 13.39 -27.6 1 3 1 28 363.868 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(1R)-1-phenylethyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.84 12.67 -10.92 0 3 0 27 362.86 5 ↓
Lo Low (pH 4.5-6) 5.84 13.33 -27.54 1 3 1 28 363.868 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-(o-tolylmethyl)benzimidazole 2-[(2-chlorophenoxy)methyl]-1-(o…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.88 13.41 -10.83 0 3 0 27 362.86 5 ↓
Lo Low (pH 4.5-6) 5.88 14 -29.76 1 3 1 28 363.868 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2,5-dimethylphenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.30 13.27 -12.07 0 3 0 27 376.887 5 ↓
Lo Low (pH 4.5-6) 6.30 13.97 -30.42 1 3 1 28 377.895 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-(m-tolylmethyl)benzimidazole 2-[(2-chlorophenoxy)methyl]-1-(m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.90 13.1 -12.06 0 3 0 27 362.86 5 ↓
Lo Low (pH 4.5-6) 5.90 13.81 -31.08 1 3 1 28 363.868 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2,3,5,6-tetramethylphenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.06 14.02 -13.78 0 3 0 27 404.941 5 ↓
Lo Low (pH 4.5-6) 7.06 14.48 -28.77 1 3 1 28 405.949 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2,4,6-trimethylphenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.68 13.35 -14.22 0 3 0 27 390.914 5 ↓
Lo Low (pH 4.5-6) 6.68 14.06 -27.99 1 3 1 28 391.922 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2,6-dichlorophenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.74 12.58 -10.2 0 3 0 27 417.723 5 ↓
Lo Low (pH 4.5-6) 6.74 13.17 -22.85 1 3 1 28 418.731 5 ↓

Analogs

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Popular Name: 1-[(2-chloro-6-fluoro-phenyl)methyl]-2-[(2-chlorophenoxy)methyl]benzimidazole 1-[(2-chloro-6-fluoro-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.22 12.54 -10.96 0 3 0 27 401.268 5 ↓
Lo Low (pH 4.5-6) 6.22 13.12 -24.38 1 3 1 28 402.276 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2-fluorophenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.59 12.32 -13.37 0 3 0 27 366.823 5 ↓
Lo Low (pH 4.5-6) 5.59 13.02 -32.27 1 3 1 28 367.831 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2-chlorophenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.11 12.53 -12.47 0 3 0 27 383.278 5 ↓
Lo Low (pH 4.5-6) 6.11 13.24 -31.1 1 3 1 28 384.286 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2,4-dichlorophenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.76 13.21 -11.4 0 3 0 27 417.723 5 ↓
Lo Low (pH 4.5-6) 6.76 13.73 -34.4 1 3 1 28 418.731 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(4-chlorophenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.16 12.96 -12.46 0 3 0 27 383.278 5 ↓
Lo Low (pH 4.5-6) 6.16 13.67 -35.11 1 3 1 28 384.286 5 ↓

Analogs

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Popular Name: 1-[(3-bromophenyl)methyl]-2-[(2-chlorophenoxy)methyl]benzimidazole 1-[(3-bromophenyl)methyl]-2-[(2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.26 13.05 -11.92 0 3 0 27 427.729 5 ↓
Lo Low (pH 4.5-6) 6.26 13.77 -32.26 1 3 1 28 428.737 5 ↓

Analogs

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Popular Name: 1-[(4-bromophenyl)methyl]-2-[(2-chlorophenoxy)methyl]benzimidazole 1-[(4-bromophenyl)methyl]-2-[(2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.29 13.06 -12.41 0 3 0 27 427.729 5 ↓
Lo Low (pH 4.5-6) 6.29 13.77 -35.16 1 3 1 28 428.737 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(4-fluorophenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.64 12.51 -13.02 0 3 0 27 366.823 5 ↓
Lo Low (pH 4.5-6) 5.64 13.21 -36.09 1 3 1 28 367.831 5 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(4-methoxyphenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.54 11.74 -13.41 0 4 0 36 378.859 6 ↓
Lo Low (pH 4.5-6) 5.54 12.44 -33.82 1 4 1 38 379.867 6 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[[4-[(1R)-1-methylpropyl]phenyl]methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.33 15.03 -11.64 0 3 0 27 404.941 7 ↓
Lo Low (pH 4.5-6) 7.33 15.74 -30.93 1 3 1 28 405.949 7 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[[4-[(1S)-1-methylpropyl]phenyl]methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.33 15.03 -11.6 0 3 0 27 404.941 7 ↓
Lo Low (pH 4.5-6) 7.33 15.74 -30.96 1 3 1 28 405.949 7 ↓

Analogs

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Popular Name: 1-[(4-tert-butylphenyl)methyl]-2-[(2-chlorophenoxy)methyl]benzimidazole 1-[(4-tert-butylphenyl)methyl]-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 7.19 14.76 -11.71 0 3 0 27 404.941 6 ↓
Lo Low (pH 4.5-6) 7.19 15.47 -30.98 1 3 1 28 405.949 6 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(4-isopropylphenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.99 14.37 -11.69 0 3 0 27 390.914 6 ↓
Lo Low (pH 4.5-6) 6.99 15.07 -30.96 1 3 1 28 391.922 6 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-[(2-methoxyphenyl)methyl]benzimidazole 2-[(2-chlorophenoxy)methyl]-1-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.49 11.99 -13.2 0 4 0 36 378.859 6 ↓
Lo Low (pH 4.5-6) 5.49 12.69 -30.32 1 4 1 38 379.867 6 ↓

Analogs

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Popular Name: 2-[(2-chlorophenoxy)methyl]-1-(p-tolylmethyl)benzimidazole 2-[(2-chlorophenoxy)methyl]-1-(p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.93 13.11 -12.13 0 3 0 27 362.86 5 ↓
Lo Low (pH 4.5-6) 5.93 13.82 -31.1 1 3 1 28 363.868 5 ↓

Analogs

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Popular Name: 1-[(2,5-dimethylphenyl)methyl]-2-[(2-methoxyphenoxy)methyl]benzimidazole 1-[(2,5-dimethylphenyl)methyl]-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.29 12.61 -13.67 0 4 0 36 372.468 6 ↓
Lo Low (pH 4.5-6) 5.29 13.3 -29.42 1 4 1 38 373.476 6 ↓

Analogs

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Popular Name: 2-[(2-methoxyphenoxy)methyl]-1-(m-tolylmethyl)benzimidazole 2-[(2-methoxyphenoxy)methyl]-1-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.89 12.44 -13.69 0 4 0 36 358.441 6 ↓
Lo Low (pH 4.5-6) 4.89 13.14 -30.09 1 4 1 38 359.449 6 ↓

Analogs

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Popular Name: 2-[(2-methoxyphenoxy)methyl]-1-[(2,3,5,6-tetramethylphenyl)methyl]benzimidazole 2-[(2-methoxyphenoxy)methyl]-1-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 6.04 13.36 -15.34 0 4 0 36 400.522 6 ↓
Lo Low (pH 4.5-6) 6.04 13.8 -28.06 1 4 1 38 401.53 6 ↓

Analogs

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Popular Name: 2-[(2-methoxyphenoxy)methyl]-1-[(2,4,6-trimethylphenyl)methyl]benzimidazole 2-[(2-methoxyphenoxy)methyl]-1-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.66 12.69 -15.98 0 4 0 36 386.495 6 ↓
Lo Low (pH 4.5-6) 5.66 13.38 -27.45 1 4 1 38 387.503 6 ↓

Parameters Provided:

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Structural Results Found: (before additional filtering)

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