UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 1-[2-(cyclopentylamino)-2-oxo-ethyl]-N,N,3,5-tetramethyl-pyrazole-4-carboxamide 1-[2-(cyclopentylamino)-2-oxo-et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.23 -0.64 -16.59 1 6 0 67 292.383 4 ↓

Analogs

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Popular Name: N-cyclopentyl-2-(4-formyl-3,5-dimethyl-pyrazol-1-yl)acetamide N-cyclopentyl-2-(4-formyl-3,5-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 4.66 -18.25 1 5 0 64 249.314 4 ↓

Analogs

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Popular Name: N-cyclopentyl-2-[4-(hydroxymethyl)-3,5-dimethyl-pyrazol-1-yl]acetamide N-cyclopentyl-2-[4-(hydroxymethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 2.11 -17.31 2 5 0 67 251.33 4 ↓

Analogs

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Popular Name: 2-[4-(aminomethyl)-3,5-dimethyl-pyrazol-1-yl]-N-cyclopentyl-acetamide 2-[4-(aminomethyl)-3,5-dimethyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.45 2.82 -49.34 4 5 1 75 251.354 4 ↓
Hi High (pH 8-9.5) 0.45 2.42 -14.32 3 5 0 73 250.346 4 ↓

Analogs

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Popular Name: N-cyclopentyl-2-[3,5-dimethyl-4-(methylaminomethyl)pyrazol-1-yl]acetamide N-cyclopentyl-2-[3,5-dimethyl-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.82 4.7 -44.14 3 5 1 64 265.381 5 ↓
Hi High (pH 8-9.5) 0.82 3.25 -13.61 2 5 0 59 264.373 5 ↓

Analogs

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Popular Name: N-cyclopentyl-2-[4-(ethylaminomethyl)-3,5-dimethyl-pyrazol-1-yl]acetamide N-cyclopentyl-2-[4-(ethylaminome…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.20 5.6 -43.8 3 5 1 64 279.408 6 ↓
Hi High (pH 8-9.5) 1.20 4.24 -13.32 2 5 0 59 278.4 6 ↓

Analogs

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Popular Name: N-cyclopentyl-2-[3,5-dimethyl-4-(propylaminomethyl)pyrazol-1-yl]acetamide N-cyclopentyl-2-[3,5-dimethyl-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 6.36 -44.51 3 5 1 64 293.435 7 ↓
Hi High (pH 8-9.5) 1.70 5 -13.21 2 5 0 59 292.427 7 ↓

Analogs

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Popular Name: N-cyclopentyl-2-[4-[(isopropylamino)methyl]-3,5-dimethyl-pyrazol-1-yl]acetamide N-cyclopentyl-2-[4-[(isopropylam…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.50 6.08 -41.76 3 5 1 64 293.435 6 ↓
Hi High (pH 8-9.5) 1.50 4.88 -13.2 2 5 0 59 292.427 6 ↓

Analogs

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Popular Name: N-cyclopentyl-2-[4-(2,2,2-trifluoroethylcarbamoylamino)pyrazol-1-yl]acetamide N-cyclopentyl-2-[4-(2,2,2-triflu…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 2.71 -21.49 3 7 0 88 333.314 6 ↓

Analogs

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Popular Name: N-[1-[2-(cyclopentylamino)-2-oxo-ethyl]pyrazol-4-yl]-2-ethyl-butanamide N-[1-[2-(cyclopentylamino)-2-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.13 5.56 -21.37 2 6 0 76 306.41 7 ↓

Analogs

2782072
2782072
2782073
2782073
2782074
2782074
2782384
2782384
826498
826498

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Popular Name: 2-[4-bromo-3-(difluoromethyl)-5-methyl-pyrazol-1-yl]-N-cyclopentyl-acetamide 2-[4-bromo-3-(difluoromethyl)-5-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.63 -0.14 -15.72 1 4 0 46 336.18 4 ↓

Analogs

2781743
2781743

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Popular Name: (2S)-N-cyclopentyl-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]propionamide (2S)-N-cyclopentyl-2-[5-methyl-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.61 1.73 -15.99 1 4 0 46 289.301 4 ↓

Analogs

2781742
2781742

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Popular Name: (2R)-N-cyclopentyl-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]propionamide (2R)-N-cyclopentyl-2-[5-methyl-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.61 1.79 -15.81 1 4 0 46 289.301 4 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 5.62 -17.8 1 6 0 73 279.34 5 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.16 6.31 -21.69 1 6 0 73 333.31 7 ↓

Analogs

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Popular Name: 2-(3-amino-4-chloro-pyrazol-1-yl)-N-cyclopentyl-acetamide 2-(3-amino-4-chloro-pyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 3.27 -14.87 3 5 0 73 242.71 3 ↓

Analogs

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Popular Name: 1H-pyrazole-1-acetamide, 3-amino-N-cyclopentyl-4-methyl- 1H-pyrazole-1-acetamide, 3-amino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 3.44 -15.81 3 5 0 73 222.292 3 ↓

Analogs

42350131
42350131
42350132
42350132

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Popular Name: 2-(4-bromo-3-nitro-pyrazol-1-yl)-N-cyclopentyl-acetamide 2-(4-bromo-3-nitro-pyrazol-1-yl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.71 6.13 -21.2 1 7 0 93 317.143 4 ↓

Analogs

36778026
36778026
36778027
36778027
36778028
36778028
36778029
36778029
36778066
36778066

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Popular Name: (2S)-N-cyclopentyl-2-(3,5-dimethylpyrazol-1-yl)propanamide (2S)-N-cyclopentyl-2-(3,5-dimeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 5.64 -14.99 1 4 0 47 235.331 3 ↓

Analogs

36778026
36778026
36778027
36778027
36778028
36778028
36778029
36778029
36778066
36778066

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Popular Name: (2R)-N-cyclopentyl-2-(3,5-dimethylpyrazol-1-yl)propanamide (2R)-N-cyclopentyl-2-(3,5-dimeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 5.63 -14.97 1 4 0 47 235.331 3 ↓

Analogs

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Popular Name: 1-[[(2S)-2-pyrazol-1-ylpropanoyl]amino]cyclopentanecarboxylic 1-[[(2S)-2-pyrazol-1-ylpropanoyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.41 5.44 -65.06 1 6 -1 87 250.278 4 ↓

Analogs

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Popular Name: 1-[[(2R)-2-pyrazol-1-ylpropanoyl]amino]cyclopentanecarboxylic 1-[[(2R)-2-pyrazol-1-ylpropanoyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.41 5.43 -59.67 1 6 -1 87 250.278 4 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

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