ZINC 12

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ZINC Item

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12016153

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-2-methoxy-N-methyl-N-phenyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.81	-6.09	-17.62	0	7	0	84	410.517	5	↓ MOL2 SDF SMILES Flexibase

12016156

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-chlorophenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methoxy-benzenesulfonamide N-(2-chlorophenyl)-5-(1,1-dioxot…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.20	-7.95	-18.6	1	7	0	93	430.935	5	↓ MOL2 SDF SMILES Flexibase

12016157

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chlorophenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methoxy-benzenesulfonamide N-(3-chlorophenyl)-5-(1,1-dioxot…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.22	-7.39	-26.14	1	7	0	93	430.935	5	↓ MOL2 SDF SMILES Flexibase

12016158

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-chlorophenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methoxy-benzenesulfonamide N-(4-chlorophenyl)-5-(1,1-dioxot…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.25	-7.62	-22.55	1	7	0	93	430.935	5	↓ MOL2 SDF SMILES Flexibase

12016159

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-4-fluoro-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methoxy-benzenesulfonamide N-(3-chloro-4-fluoro-phenyl)-5-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.34	-6.95	-20.75	1	7	0	93	448.925	5	↓ MOL2 SDF SMILES Flexibase

12016160

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chloro-4-methoxy-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methoxy-benzenesulfonamide N-(3-chloro-4-methoxy-phenyl)-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.23	-7.57	-21.93	1	8	0	102	460.961	6	↓ MOL2 SDF SMILES Flexibase

12016161

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.35	-6.52	-21	1	9	0	119	488.971	7	↓ MOL2 SDF SMILES Flexibase

12209027

Analogs

12209038
12209044

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-2-methyl-N-phenyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.96	4.67	-17.71	1	6	0	84	380.491	4	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	2.96	4.75	-47.1	0	6	-1	86	379.483	4	↓ MOL2 SDF SMILES Flexibase

12209028

Analogs

12209056
12209075
12209108

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-2-methyl-N-(o-tolyl)benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	-6.81	-16.03	1	6	0	84	394.518	4	↓ MOL2 SDF SMILES Flexibase

12209033

Analogs

12209069

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-2-methyl-N-(m-tolyl)benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	-6.98	-15.82	1	6	0	84	394.518	4	↓ MOL2 SDF SMILES Flexibase

12209038

Analogs

12209044
12209027

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-2-methyl-N-(p-tolyl)benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.41	-6.97	-16.42	1	6	0	84	394.518	4	↓ MOL2 SDF SMILES Flexibase

12209044

Analogs

12209096
12209038
12209027

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N,2-dimethyl-N-phenyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N,2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.21	-6.06	-18.62	0	6	0	75	394.518	4	↓ MOL2 SDF SMILES Flexibase

12209056

Analogs

12209075
12209108
12209028

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2,4-dimethylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.79	-6.49	-16.04	1	6	0	84	408.545	4	↓ MOL2 SDF SMILES Flexibase

12209061

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2,5-dimethylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.79	-6.49	-23.7	1	6	0	84	408.545	4	↓ MOL2 SDF SMILES Flexibase

12209066

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,4-dimethylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3,4-dimethylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.79	-6.63	-16.58	1	6	0	84	408.545	4	↓ MOL2 SDF SMILES Flexibase

12209069

Analogs

12209033

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,5-dimethylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3,5-dimethylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.79	-6.65	-16.56	1	6	0	84	408.545	4	↓ MOL2 SDF SMILES Flexibase

12209075

Analogs

12209108
12209028
12209056

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,6-dimethylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2,6-dimethylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	-6.43	-15.76	1	6	0	84	408.545	4	↓ MOL2 SDF SMILES Flexibase

12209081

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,3-dimethylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2,3-dimethylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	-6.31	-24.1	1	6	0	84	408.545	4	↓ MOL2 SDF SMILES Flexibase

12209084

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-ethylphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.83	-6.72	-15.73	1	6	0	84	408.545	5	↓ MOL2 SDF SMILES Flexibase

12209090

Analogs

12209105
12209127

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(4-ethylphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.87	-6.82	-16.29	1	6	0	84	408.545	5	↓ MOL2 SDF SMILES Flexibase

12209096

Analogs

12209044

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-ethyl-2-methyl-N-phenyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.58	-6	-16.69	0	6	0	75	408.545	5	↓ MOL2 SDF SMILES Flexibase

12209097

Analogs

12209113

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-ethyl-6-methyl-phenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.23	-6.2	-15.87	1	6	0	84	422.572	5	↓ MOL2 SDF SMILES Flexibase

12209101

Analogs

12209122

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-isopropylphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	-6.29	-15.55	1	6	0	84	422.572	5	↓ MOL2 SDF SMILES Flexibase

12209105

Analogs

12209127
12209090

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(4-isopropylphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.47	-6.5	-16.1	1	6	0	84	422.572	5	↓ MOL2 SDF SMILES Flexibase

12209108

Analogs

12209028
12209056
12209075

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-2-methyl-N-(2,4,6-trimethylphenyl)benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.16	-5.99	-15.89	1	6	0	84	422.572	4	↓ MOL2 SDF SMILES Flexibase

12209113

Analogs

12209097

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,6-diethylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2,6-diethylphenyl)-5-(1,1-dio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.69	-6.26	-15.82	1	6	0	84	436.599	6	↓ MOL2 SDF SMILES Flexibase

12209118

Analogs

12209407

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-isopropyl-6-methyl-phenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.35	-5.88	-15.66	1	6	0	84	436.599	5	↓ MOL2 SDF SMILES Flexibase

12209122

Analogs

12209101

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-tert-butylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2-tert-butylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.62	-5.95	-23.76	1	6	0	84	436.599	5	↓ MOL2 SDF SMILES Flexibase

12209127

Analogs

12209090
12209105

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-tert-butylphenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(4-tert-butylphenyl)-5-(1,1-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.67	-6.14	-16.07	1	6	0	84	436.599	5	↓ MOL2 SDF SMILES Flexibase

12209132

Analogs

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Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-fluorophenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.08	-6.53	-16.08	1	6	0	84	398.481	4	↓ MOL2 SDF SMILES Flexibase

12209136

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(4-fluorophenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.12	-6.56	-16.68	1	6	0	84	398.481	4	↓ MOL2 SDF SMILES Flexibase

12209139

Analogs

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Popular Name: N-(2-chlorophenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2-chlorophenyl)-5-(1,1-dioxot…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.59	-7.33	-15.36	1	6	0	84	414.936	4	↓ MOL2 SDF SMILES Flexibase

12209141

Analogs

12209165

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chlorophenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3-chlorophenyl)-5-(1,1-dioxot…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.61	-7.84	-23.61	1	6	0	84	414.936	4	↓ MOL2 SDF SMILES Flexibase

12209146

Analogs

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Popular Name: N-(4-chlorophenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(4-chlorophenyl)-5-(1,1-dioxot…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.64	-7.44	-16.19	1	6	0	84	414.936	4	↓ MOL2 SDF SMILES Flexibase

12209150

Analogs

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Popular Name: N-(3-chloro-2-methyl-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3-chloro-2-methyl-phenyl)-5-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.99	-6.69	-21.29	1	6	0	84	428.963	4	↓ MOL2 SDF SMILES Flexibase

12209155

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(5-chloro-2-methyl-phenyl)-5-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.01	-6.96	-16.23	1	6	0	84	428.963	4	↓ MOL2 SDF SMILES Flexibase

12209161

Analogs

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Popular Name: N-(4-chloro-2-methyl-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(4-chloro-2-methyl-phenyl)-5-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.01	-6.96	-15.88	1	6	0	84	428.963	4	↓ MOL2 SDF SMILES Flexibase

12209165

Analogs

12209141

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Popular Name: N-(3-chloro-4-methyl-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3-chloro-4-methyl-phenyl)-5-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.01	-7.5	-23.15	1	6	0	84	428.963	4	↓ MOL2 SDF SMILES Flexibase

12209170

Analogs

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Popular Name: N-(3-chloro-4-fluoro-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3-chloro-4-fluoro-phenyl)-5-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.73	-7.11	-22.75	1	6	0	84	432.926	4	↓ MOL2 SDF SMILES Flexibase

12209173

Analogs

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Popular Name: N-(2-chloro-4,6-dimethyl-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(2-chloro-4,6-dimethyl-phenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.39	-6.49	-18.02	1	6	0	84	442.99	4	↓ MOL2 SDF SMILES Flexibase

12209177

Analogs

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Popular Name: N-(3-chloro-4-methoxy-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3-chloro-4-methoxy-phenyl)-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.62	-7.76	-24.65	1	7	0	93	444.962	5	↓ MOL2 SDF SMILES Flexibase

12209181

Analogs

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Popular Name: N-(5-chloro-2-methoxy-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(5-chloro-2-methoxy-phenyl)-5-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.62	-7.37	-15.9	1	7	0	93	444.962	5	↓ MOL2 SDF SMILES Flexibase

12209187

Analogs

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Popular Name: N-(4-bromophenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(4-bromophenyl)-5-(1,1-dioxoth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	-8.05	-16.12	1	6	0	84	459.387	4	↓ MOL2 SDF SMILES Flexibase

12209188

Analogs

12209381

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Popular Name: N-(3-bromo-4-methyl-phenyl)-5-(1,1-dioxothiazinan-2-yl)-2-methyl-benzenesulfonamide N-(3-bromo-4-methyl-phenyl)-5-(1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.14	-8.08	-23.13	1	6	0	84	473.414	4	↓ MOL2 SDF SMILES Flexibase

12209194

Analogs

12209236

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Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-methoxyphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.97	-7.22	-16.48	1	7	0	93	410.517	5	↓ MOL2 SDF SMILES Flexibase

12209200

Analogs

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Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(3-methoxyphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.99	-7.67	-24.77	1	7	0	93	410.517	5	↓ MOL2 SDF SMILES Flexibase

12209205

Analogs

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Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(4-methoxyphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.02	-7.29	-17.51	1	7	0	93	410.517	5	↓ MOL2 SDF SMILES Flexibase

12209211

Analogs

12209224

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-ethoxyphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.34	-7.2	-16.19	1	7	0	93	424.544	6	↓ MOL2 SDF SMILES Flexibase

12209216

Analogs

12209229

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(4-ethoxyphenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.39	-7.27	-17.36	1	7	0	93	424.544	6	↓ MOL2 SDF SMILES Flexibase

12209220

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(1,1-dioxothiazinan-2-yl)-N-(2-methoxy-5-methyl-phenyl)-2-methyl-benzenesulfonamide 5-(1,1-dioxothiazinan-2-yl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.39	-6.62	-23.57	1	7	0	93	424.544	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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SQL Query Was

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