UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

39703647
39703647
39703651
39703651

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Popular Name: (3-methoxyphenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]dec-8-yl]-methanone (3-methoxyphenyl)-[4-(2-thienyls…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 -4.58 -17.54 0 7 0 76 422.528 4 ↓

Analogs

20614800
20614800
39703640
39703640
39703651
39703651

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Popular Name: (4-ethoxyphenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]dec-8-yl]-methanone (4-ethoxyphenyl)-[4-(2-thienylsu…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 -4.55 -15.41 0 7 0 76 436.555 5 ↓

Analogs

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Popular Name: (4-bromophenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]dec-8-yl]-methanone (4-bromophenyl)-[4-(2-thienylsul…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.89 -5.36 -13.48 0 6 0 66 471.398 3 ↓

Analogs

39703640
39703640
39703649
39703649
39703651
39703651
39703670
39703670
39703671
39703671

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Popular Name: (4-methoxyphenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decan-8-yl]methanone (4-methoxyphenyl)-[4-(2-thienyls…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 4.39 -15.84 0 7 0 76 422.528 4 ↓

Analogs

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Popular Name: (3,4-difluorophenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decan-8-yl]methanone (3,4-difluorophenyl)-[4-(2-thien…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.34 5.2 -14.58 0 6 0 67 428.482 3 ↓

Analogs

39703676
39703676

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Popular Name: (4-nitrophenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decan-8-yl]methanone (4-nitrophenyl)-[4-(2-thienylsul…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.04 5.74 -14.77 0 9 0 113 437.499 4 ↓

Analogs

21114309
21114309

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Popular Name: (3,4-dimethoxyphenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decan-8-yl]methanone (3,4-dimethoxyphenyl)-[4-(2-thie…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.73 4.32 -17.59 0 8 0 85 452.554 5 ↓

Analogs

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Popular Name: (4-chloro-3-nitro-phenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decan-8-yl]methanone (4-chloro-3-nitro-phenyl)-[4-(2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.65 6.12 -17.27 0 9 0 113 471.944 4 ↓

Analogs

39703652
39703652

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Popular Name: (2-chloro-6-fluoro-phenyl)-[4-(2-thienylsulfonyl)-1-oxa-4,8-diazaspiro[4.5]decan-8-yl]methanone (2-chloro-6-fluoro-phenyl)-[4-(2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 5.76 -17.65 0 6 0 67 444.937 3 ↓

Parameters Provided:

ring.id = 8143
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 8143 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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