ZINC 12

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.86	8.17	-13.42	1	5	0	51	340.423	5	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.86	8.82	-44.24	2	5	1	52	341.431	5	↓ MOL2 SDF SMILES Flexibase

69698375

Analogs

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Popular Name: 2-chloro-N-[1-(4-methoxyphenyl)-4-piperidyl]benzamide 2-chloro-N-[1-(4-methoxyphenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.94	8.13	-11.64	1	4	0	42	344.842	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.94	8.79	-43.72	2	4	1	43	345.85	4	↓ MOL2 SDF SMILES Flexibase

69699023

Analogs

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Popular Name: 2,4-difluoro-N-[1-(4-methoxyphenyl)-4-piperidyl]benzamide 2,4-difluoro-N-[1-(4-methoxyphen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	7.77	-12.96	1	4	0	42	346.377	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.56	8.43	-47.19	2	4	1	43	347.385	4	↓ MOL2 SDF SMILES Flexibase

69705102

Analogs

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Popular Name: 4-fluoro-N-[1-(4-methoxyphenyl)-4-piperidyl]benzamide 4-fluoro-N-[1-(4-methoxyphenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.47	7.69	-9.93	1	4	0	42	328.387	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.47	8.34	-43.86	2	4	1	43	329.395	4	↓ MOL2 SDF SMILES Flexibase

69709682

Analogs

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Popular Name: 3-fluoro-N-[1-(4-methoxyphenyl)-4-piperidyl]benzamide 3-fluoro-N-[1-(4-methoxyphenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.44	7.68	-12.15	1	4	0	42	328.387	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.44	8.34	-45.93	2	4	1	43	329.395	4	↓ MOL2 SDF SMILES Flexibase

69709820

Analogs

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Popular Name: 3-methoxy-N-[1-(4-methoxyphenyl)-4-piperidyl]benzamide 3-methoxy-N-[1-(4-methoxyphenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.34	6.92	-13.06	1	5	0	51	340.423	5	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.34	7.57	-45.42	2	5	1	52	341.431	5	↓ MOL2 SDF SMILES Flexibase

65530707

Analogs

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Popular Name: 2-fluoro-N-[1-(4-methoxyphenyl)-4-piperidyl]benzamide 2-fluoro-N-[1-(4-methoxyphenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.42	7.69	-14.27	1	4	0	42	328.387	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.42	8.35	-46.3	2	4	1	43	329.395	4	↓ MOL2 SDF SMILES Flexibase

69740892

Analogs

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Popular Name: N-[1-(4-methoxyphenyl)-4-piperidyl]-2-methyl-benzamide N-[1-(4-methoxyphenyl)-4-piperid…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.70	8.29	-9.33	1	4	0	42	324.424	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.70	8.95	-41.27	2	4	1	43	325.432	4	↓ MOL2 SDF SMILES Flexibase

56166156

Analogs

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Popular Name: N-(1-phenyl-4-piperidyl)-3-ureido-benzamide N-(1-phenyl-4-piperidyl)-3-ureid…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.36	4.4	-20.37	4	6	0	87	338.411	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	2.36	5.04	-48.96	5	6	1	89	339.419	4	↓ MOL2 SDF SMILES Flexibase

69876410

Analogs

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Popular Name: 2,5-difluoro-N-[1-(4-methoxyphenyl)-4-piperidyl]benzamide 2,5-difluoro-N-[1-(4-methoxyphen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.56	7.76	-11.45	1	4	0	42	346.377	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.56	8.42	-43.87	2	4	1	43	347.385	4	↓ MOL2 SDF SMILES Flexibase

37276611

Analogs

35810455
35810456
35810585

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Popular Name: 2-[4-[(2-methylbenzoyl)amino]-1-piperidyl]-N-propyl-benzamide 2-[4-[(2-methylbenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	10.02	-14.66	2	5	0	61	379.504	6	↓ MOL2 SDF SMILES Flexibase

37276613

Analogs

35810418
35810741

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Popular Name: 2-[4-[(4-nitrobenzoyl)amino]-1-piperidyl]-N-propyl-benzamide 2-[4-[(4-nitrobenzoyl)amino]-1-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.23	10.06	-16.73	2	8	0	107	410.474	7	↓ MOL2 SDF SMILES Flexibase

37276622

Analogs

35810413

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Popular Name: N-[1-[2-(tert-butylcarbamoyl)phenyl]-4-piperidyl]-4-methyl-benzamide N-[1-[2-(tert-butylcarbamoyl)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.03	10.58	-14.47	2	5	0	61	393.531	5	↓ MOL2 SDF SMILES Flexibase

37276628

Analogs

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Popular Name: N-[1-[2-(tert-butylcarbamoyl)phenyl]-4-piperidyl]-2,4-dichloro-benzamide N-[1-[2-(tert-butylcarbamoyl)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.86	10.93	-14.29	2	5	0	61	448.394	5	↓ MOL2 SDF SMILES Flexibase

37276630

Analogs

35810455
35810456
35810585

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Popular Name: N-[1-[2-(tert-butylcarbamoyl)phenyl]-4-piperidyl]-2-methyl-benzamide N-[1-[2-(tert-butylcarbamoyl)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.98	10.57	-13.46	2	5	0	61	393.531	5	↓ MOL2 SDF SMILES Flexibase

37276632

Analogs

35810419

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Popular Name: N-[1-[2-(tert-butylcarbamoyl)phenyl]-4-piperidyl]-4-ethyl-benzamide N-[1-[2-(tert-butylcarbamoyl)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.49	11.35	-14.2	2	5	0	61	407.558	6	↓ MOL2 SDF SMILES Flexibase

37276654

Analogs

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Popular Name: 2-[4-[(2-chlorobenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(2-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.65	11.26	-16.74	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276657

Analogs

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Popular Name: 2-[4-[(2-chlorobenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(2-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.65	11.26	-16.74	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276659

Analogs

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Popular Name: 2-[4-[(4-methoxybenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(4-methoxybenzoyl)amino]-1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.08	10.07	-15.46	2	6	0	71	423.557	8	↓ MOL2 SDF SMILES Flexibase

37276662

Analogs

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Popular Name: 2-[4-[(4-methoxybenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(4-methoxybenzoyl)amino]-1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.08	10.08	-15.49	2	6	0	71	423.557	8	↓ MOL2 SDF SMILES Flexibase

37276668

Analogs

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Popular Name: 2-[4-[(4-methylbenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(4-methylbenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.47	11.42	-15.25	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276671

Analogs

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Popular Name: 2-[4-[(4-methylbenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(4-methylbenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.47	11.43	-15.23	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276679

Analogs

35810595

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Popular Name: 2-[4-[(4-chlorobenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(4-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	11.26	-14.05	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276681

Analogs

35810595

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Popular Name: 2-[4-[(4-chlorobenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(4-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	11.27	-14.06	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276688

Analogs

35810597

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Popular Name: 2,4-dichloro-N-[1-[2-[[(2R)-2-methylbutyl]carbamoyl]phenyl]-4-piperidyl]benzamide 2,4-dichloro-N-[1-[2-[[(2R)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.30	11.78	-15.22	2	5	0	61	462.421	7	↓ MOL2 SDF SMILES Flexibase

37276691

Analogs

35810597

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Popular Name: 2,4-dichloro-N-[1-[2-[[(2S)-2-methylbutyl]carbamoyl]phenyl]-4-piperidyl]benzamide 2,4-dichloro-N-[1-[2-[[(2S)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.30	11.79	-15.27	2	5	0	61	462.421	7	↓ MOL2 SDF SMILES Flexibase

37276693

Analogs

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Popular Name: 2-[4-[(2-methylbenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(2-methylbenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.42	11.42	-14.26	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276696

Analogs

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Popular Name: 2-[4-[(2-methylbenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(2-methylbenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.42	11.42	-14.33	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276698

Analogs

52303395
52303396
52303400
52303402
52303405

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Popular Name: 2-[4-[(3-chlorobenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(3-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.67	11.25	-16.14	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276701

Analogs

52303395
52303396
52303400
52303402
52303405

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Popular Name: 2-[4-[(3-chlorobenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(3-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.67	11.26	-16.2	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276703

Analogs

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Popular Name: 2-[4-[(2-methoxybenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(2-methoxybenzoyl)amino]-1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.58	11.3	-18.54	2	6	0	71	423.557	8	↓ MOL2 SDF SMILES Flexibase

37276705

Analogs

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Popular Name: 2-[4-[(2-methoxybenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(2-methoxybenzoyl)amino]-1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.58	11.31	-18.62	2	6	0	71	423.557	8	↓ MOL2 SDF SMILES Flexibase

37276708

Analogs

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Popular Name: 2-[4-[(3-methylbenzoyl)amino]-1-piperidyl]-N-[(2R)-2-methylbutyl]benzamide 2-[4-[(3-methylbenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.44	11.41	-15.46	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276711

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[(3-methylbenzoyl)amino]-1-piperidyl]-N-[(2S)-2-methylbutyl]benzamide 2-[4-[(3-methylbenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.44	11.42	-15.49	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276713

Analogs

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Popular Name: 4-ethyl-N-[1-[2-[[(2S)-2-methylbutyl]carbamoyl]phenyl]-4-piperidyl]benzamide 4-ethyl-N-[1-[2-[[(2S)-2-methylb…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.93	12.2	-15.06	2	5	0	61	421.585	8	↓ MOL2 SDF SMILES Flexibase

37276716

Analogs

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Popular Name: 4-ethyl-N-[1-[2-[[(2R)-2-methylbutyl]carbamoyl]phenyl]-4-piperidyl]benzamide 4-ethyl-N-[1-[2-[[(2R)-2-methylb…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.93	12.2	-15.07	2	5	0	61	421.585	8	↓ MOL2 SDF SMILES Flexibase

37276720

Analogs

35810417

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Popular Name: 3,4-dichloro-N-[1-[2-[3-(dimethylamino)propylcarbamoyl]phenyl]-4-piperidyl]benzamide 3,4-dichloro-N-[1-[2-[3-(dimethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.98	11.63	-49.07	3	6	1	66	478.444	8	↓ MOL2 SDF SMILES Flexibase

37276743

Analogs

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Popular Name: 2-[4-[(2-chlorobenzoyl)amino]-1-piperidyl]-N-isopentyl-benzamide 2-[4-[(2-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.68	11.14	-16.91	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276745

Analogs

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Popular Name: N-isopentyl-2-[4-[(4-methoxybenzoyl)amino]-1-piperidyl]benzamide N-isopentyl-2-[4-[(4-methoxybenz…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.10	9.95	-15.68	2	6	0	71	423.557	8	↓ MOL2 SDF SMILES Flexibase

37276750

Analogs

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Popular Name: N-[1-[2-(isopentylcarbamoyl)phenyl]-4-piperidyl]-4-methyl-benzamide N-[1-[2-(isopentylcarbamoyl)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.50	11.32	-15.56	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276757

Analogs

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Popular Name: 2-[4-[(4-chlorobenzoyl)amino]-1-piperidyl]-N-isopentyl-benzamide 2-[4-[(4-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.72	11.15	-14.28	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276761

Analogs

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Popular Name: N-[1-[2-(isopentylcarbamoyl)phenyl]-4-piperidyl]-2-methyl-benzamide N-[1-[2-(isopentylcarbamoyl)phen…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.45	11.31	-14.5	2	5	0	61	407.558	7	↓ MOL2 SDF SMILES Flexibase

37276763

Analogs

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Popular Name: N-isopentyl-2-[4-[(4-nitrobenzoyl)amino]-1-piperidyl]benzamide N-isopentyl-2-[4-[(4-nitrobenzoy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.01	11.34	-16.49	2	8	0	107	438.528	8	↓ MOL2 SDF SMILES Flexibase

37276766

Analogs

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Popular Name: 2-[4-[(3-chlorobenzoyl)amino]-1-piperidyl]-N-isopentyl-benzamide 2-[4-[(3-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	11.14	-16.39	2	5	0	61	427.976	7	↓ MOL2 SDF SMILES Flexibase

37276775

Analogs

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Popular Name: N-allyl-2-[4-[(4-chlorobenzoyl)amino]-1-piperidyl]benzamide N-allyl-2-[4-[(4-chlorobenzoyl)a…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.72	9.65	-14.2	2	5	0	61	397.906	6	↓ MOL2 SDF SMILES Flexibase

37276777

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-[2-(allylcarbamoyl)phenyl]-4-piperidyl]-2,4-dichloro-benzamide N-[1-[2-(allylcarbamoyl)phenyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	10.19	-15.39	2	5	0	61	432.351	6	↓ MOL2 SDF SMILES Flexibase

37276783

Analogs

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Popular Name: N-[1-[2-(allylcarbamoyl)phenyl]-4-piperidyl]-4-ethyl-benzamide N-[1-[2-(allylcarbamoyl)phenyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	10.6	-15.27	2	5	0	61	391.515	7	↓ MOL2 SDF SMILES Flexibase

37276814

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[(4-chlorobenzoyl)amino]-1-piperidyl]-N-[(1R)-1,2-dimethylpropyl]benzamide 2-[4-[(4-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.52	11.13	-14.04	2	5	0	61	427.976	6	↓ MOL2 SDF SMILES Flexibase

37276816

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[4-[(4-chlorobenzoyl)amino]-1-piperidyl]-N-[(1S)-1,2-dimethylpropyl]benzamide 2-[4-[(4-chlorobenzoyl)amino]-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.52	11.42	-14.09	2	5	0	61	427.976	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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