UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 3-(1,3-dioxo-2,4-diazaspiro[4.5]dec-2-yl)-N-(4-methylsulfanylphenyl)-propanamide 3-(1,3-dioxo-2,4-diazaspiro[4.5]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.66 -2.8 -13.05 2 6 0 79 361.467 5 ↓

Analogs

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Popular Name: 2-[3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)propanoylamino]-N-(2,2,2-trifluoroethyl)benzamide 2-[3-(1,3-dioxo-2,4-diazaspiro[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 5.67 -13.51 3 8 0 108 440.422 7 ↓

Analogs

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Popular Name: 3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)-N-(3-isopropylphenyl)propanamide 3-(1,3-dioxo-2,4-diazaspiro[4.5]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.71 7.52 -11.49 2 6 0 79 357.454 5 ↓

Analogs

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Popular Name: N-(2,4-dimethoxyphenyl)-3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)propanamide N-(2,4-dimethoxyphenyl)-3-(1,3-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.27 4.32 -12.39 2 8 0 97 375.425 6 ↓

Analogs

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Popular Name: N-[5-(diethylsulfamoyl)-2-hydroxy-phenyl]-3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)propanamide N-[5-(diethylsulfamoyl)-2-hydrox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 2.6 -19.6 3 10 0 136 466.56 8 ↓

Analogs

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Popular Name: 3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)-N-(5-fluoro-2-methyl-phenyl)propanamide 3-(1,3-dioxo-2,4-diazaspiro[4.5]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 6.54 -13.88 2 6 0 79 347.39 4 ↓

Analogs

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Popular Name: N-(3-acetylphenyl)-3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)propanamide N-(3-acetylphenyl)-3-(1,3-dioxo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 6 -20.08 2 7 0 96 357.41 5 ↓

Analogs

15192948
15192948
25764364
25764364
25884663
25884663

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Popular Name: N-(4-acetamidophenyl)-3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)propanamide N-(4-acetamidophenyl)-3-(1,3-dio…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 4.52 -16.99 3 8 0 108 372.425 5 ↓

Analogs

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Popular Name: 4-[3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)propanoylamino]-N,N-diethyl-benzamide 4-[3-(1,3-dioxo-2,4-diazaspiro[4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 7.33 -18.77 2 8 0 99 414.506 7 ↓

Analogs

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Popular Name: N-(4-acetylphenyl)-3-(1,3-dioxo-2,4-diazaspiro[4.5]decan-2-yl)propanamide N-(4-acetylphenyl)-3-(1,3-dioxo-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 6.02 -14.43 2 7 0 96 357.41 5 ↓

Parameters Provided:

ring.id = 85464
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 85464 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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