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61430612

Analogs

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Popular Name: N-(2-carbamoylphenyl)-3,6-dimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-carbamoylphenyl)-3,6-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.02	2.06	-27.63	3	8	0	120	326.312	3	↓ MOL2 SDF SMILES Flexibase

65321297

Analogs

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Popular Name: N-(4-bromo-2-fluoro-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(4-bromo-2-fluoro-phenyl)-3-is…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.23	7.4	-17.46	1	6	0	77	422.254	4	↓ MOL2 SDF SMILES Flexibase

65321298

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(5-chloro-2-methyl-phenyl)-3-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.39	8.05	-21.62	1	6	0	77	373.84	4	↓ MOL2 SDF SMILES Flexibase

65329480

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-N,3,6-trimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(5-chloro-2-methyl-phenyl)-N,3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.51	8.04	-23.48	0	6	0	68	345.786	2	↓ MOL2 SDF SMILES Flexibase

65329481

Analogs

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Popular Name: N-(4-fluorophenyl)-3,6-dimethyl-4-oxo-N-propyl-furo[2,3-d]pyrimidine-5-carboxamide N-(4-fluorophenyl)-3,6-dimethyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.50	8	-20.37	0	6	0	68	343.358	4	↓ MOL2 SDF SMILES Flexibase

65329482

Analogs

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Popular Name: N-(3-chlorophenyl)-N,3,6-trimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3-chlorophenyl)-N,3,6-trimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.11	7.07	-21.16	0	6	0	68	331.759	2	↓ MOL2 SDF SMILES Flexibase

65329483

Analogs

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Popular Name: N-(3,4-dimethylphenyl)-N,3,6-trimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3,4-dimethylphenyl)-N,3,6-tri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.28	7.75	-23.52	0	6	0	68	325.368	2	↓ MOL2 SDF SMILES Flexibase

65329484

Analogs

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Popular Name: N-ethyl-3,6-dimethyl-N-(m-tolyl)-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-ethyl-3,6-dimethyl-N-(m-tolyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.26	7.84	-22.13	0	6	0	68	325.368	3	↓ MOL2 SDF SMILES Flexibase

65329485

Analogs

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Popular Name: N-(2-chlorophenyl)-N,3,6-trimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-chlorophenyl)-N,3,6-trimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	7.41	-22.08	0	6	0	68	331.759	2	↓ MOL2 SDF SMILES Flexibase

65329486

Analogs

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Popular Name: N-(2,5-dimethylphenyl)-N-ethyl-3,6-dimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2,5-dimethylphenyl)-N-ethyl-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.66	8.63	-23.55	0	6	0	68	339.395	3	↓ MOL2 SDF SMILES Flexibase

65329487

Analogs

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Popular Name: N,3,6-trimethyl-N-(m-tolyl)-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N,3,6-trimethyl-N-(m-tolyl)-4-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	7.19	-23.25	0	6	0	68	311.341	2	↓ MOL2 SDF SMILES Flexibase

65329499

Analogs

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Popular Name: dimethyl dimethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.48	6.14	-26.51	1	10	0	130	399.359	6	↓ MOL2 SDF SMILES Flexibase

65329505

Analogs

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Popular Name: 3,6-dimethyl-4-oxo-N-(4-sulfamoylphenyl)furo[2,3-d]pyrimidine-5-carboxamide 3,6-dimethyl-4-oxo-N-(4-sulfamoy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.10	-0.19	-27.9	3	9	0	137	362.367	3	↓ MOL2 SDF SMILES Flexibase

65329523

Analogs

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Popular Name: N-(4-fluorophenyl)-N,3,6-trimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(4-fluorophenyl)-N,3,6-trimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.62	6.61	-22.34	0	6	0	68	315.304	2	↓ MOL2 SDF SMILES Flexibase

65329582

Analogs

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Popular Name: 3-isobutyl-N-(2-methoxyphenyl)-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide 3-isobutyl-N-(2-methoxyphenyl)-6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.34	6.08	-21.21	1	7	0	86	355.394	5	↓ MOL2 SDF SMILES Flexibase

65329583

Analogs

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Popular Name: N-(4-fluorophenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(4-fluorophenyl)-3-isobutyl-6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.50	6.72	-19.86	1	6	0	77	343.358	4	↓ MOL2 SDF SMILES Flexibase

65329584

Analogs

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Popular Name: N-(3-chlorophenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3-chlorophenyl)-3-isobutyl-6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.99	7.18	-21.88	1	6	0	77	359.813	4	↓ MOL2 SDF SMILES Flexibase

65329585

Analogs

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Popular Name: N-(2-bromo-4-methyl-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-bromo-4-methyl-phenyl)-3-is…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.52	8.05	-18.73	1	6	0	77	418.291	4	↓ MOL2 SDF SMILES Flexibase

65329588

Analogs

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Popular Name: N-(3-fluoro-4-methyl-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3-fluoro-4-methyl-phenyl)-3-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.87	7.75	-21.15	1	6	0	77	357.385	4	↓ MOL2 SDF SMILES Flexibase

65329589

Analogs

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Popular Name: N-(3-chloro-4-fluoro-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3-chloro-4-fluoro-phenyl)-3-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.10	7.66	-21.77	1	6	0	77	377.803	4	↓ MOL2 SDF SMILES Flexibase

65329590

Analogs

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Popular Name: N-(3-chloro-4-methoxy-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3-chloro-4-methoxy-phenyl)-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.00	6.51	-23.64	1	7	0	86	389.839	5	↓ MOL2 SDF SMILES Flexibase

65329591

Analogs

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Popular Name: N-(2,4-dimethoxyphenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2,4-dimethoxyphenyl)-3-isobut…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.37	5.78	-21.5	1	8	0	96	385.42	6	↓ MOL2 SDF SMILES Flexibase

65329592

Analogs

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Popular Name: N-(2,4-difluorophenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2,4-difluorophenyl)-3-isobuty…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.59	6.83	-17.65	1	6	0	77	361.348	4	↓ MOL2 SDF SMILES Flexibase

65329593

Analogs

7001377

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Popular Name: N-(3,4-dimethoxyphenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3,4-dimethoxyphenyl)-3-isobut…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	6.26	-22.54	1	8	0	96	385.42	6	↓ MOL2 SDF SMILES Flexibase

65329595

Analogs

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Popular Name: N-(5-chloro-2-methoxy-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(5-chloro-2-methoxy-phenyl)-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.00	6.58	-20.81	1	7	0	86	389.839	5	↓ MOL2 SDF SMILES Flexibase

65329596

Analogs

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Popular Name: N-(2-fluorophenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-fluorophenyl)-3-isobutyl-6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.45	6.77	-19.89	1	6	0	77	343.358	4	↓ MOL2 SDF SMILES Flexibase

65329597

Analogs

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Popular Name: N-(2-chloro-4-fluoro-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-chloro-4-fluoro-phenyl)-3-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.10	7.34	-17.08	1	6	0	77	377.803	4	↓ MOL2 SDF SMILES Flexibase

65329598

Analogs

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Popular Name: 3-isobutyl-N-(3-methoxyphenyl)-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide 3-isobutyl-N-(3-methoxyphenyl)-6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.37	5.94	-22.32	1	7	0	86	355.394	5	↓ MOL2 SDF SMILES Flexibase

65329599

Analogs

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Popular Name: N-(4-bromo-2-methyl-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(4-bromo-2-methyl-phenyl)-3-is…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.52	8.14	-19.21	1	6	0	77	418.291	4	↓ MOL2 SDF SMILES Flexibase

65329626

Analogs

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Popular Name: N-(4-ethoxyphenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(4-ethoxyphenyl)-3-isobutyl-6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.77	6.84	-20.37	1	7	0	86	369.421	6	↓ MOL2 SDF SMILES Flexibase

65329632

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.01	8.97	-23.93	1	8	0	103	397.431	7	↓ MOL2 SDF SMILES Flexibase

65329633

Analogs

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Popular Name: N-(2-ethoxyphenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-ethoxyphenyl)-3-isobutyl-6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.72	6.99	-21.05	1	7	0	86	369.421	6	↓ MOL2 SDF SMILES Flexibase

65329637

Analogs

7001387

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Popular Name: N-(4-ethylphenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(4-ethylphenyl)-3-isobutyl-6-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.25	8.06	-19.53	1	6	0	77	353.422	5	↓ MOL2 SDF SMILES Flexibase

65329638

Analogs

7001387

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Popular Name: 3-isobutyl-N-(4-isopropylphenyl)-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide 3-isobutyl-N-(4-isopropylphenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.85	9	-20.75	1	6	0	77	367.449	5	↓ MOL2 SDF SMILES Flexibase

65329639

Analogs

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Popular Name: N-(4-chloro-2-methoxy-5-methyl-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(4-chloro-2-methoxy-5-methyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.37	7.58	-19.64	1	7	0	86	403.866	5	↓ MOL2 SDF SMILES Flexibase

65329646

Analogs

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Popular Name: N-(2-ethylphenyl)-3-isobutyl-N,6-dimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-ethylphenyl)-3-isobutyl-N,6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.44	9.83	-21.78	0	6	0	68	367.449	5	↓ MOL2 SDF SMILES Flexibase

65329647

Analogs

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Popular Name: N-(5-chloro-2-methyl-phenyl)-3-isobutyl-N,6-dimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(5-chloro-2-methyl-phenyl)-3-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.63	9.84	-22.31	0	6	0	68	387.867	4	↓ MOL2 SDF SMILES Flexibase

65329649

Analogs

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Popular Name: N-(3-chlorophenyl)-3-isobutyl-N,6-dimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3-chlorophenyl)-3-isobutyl-N,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.23	8.88	-19.65	0	6	0	68	373.84	4	↓ MOL2 SDF SMILES Flexibase

65329650

Analogs

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Popular Name: N-(5-chloro-2-methoxy-phenyl)-3-isobutyl-N,6-dimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(5-chloro-2-methoxy-phenyl)-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.24	8.77	-23.08	0	7	0	78	403.866	5	↓ MOL2 SDF SMILES Flexibase

65329651

Analogs

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Popular Name: N-(2-fluorophenyl)-3-isobutyl-N,6-dimethyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-fluorophenyl)-3-isobutyl-N,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.69	8.95	-21.93	0	6	0	68	357.385	4	↓ MOL2 SDF SMILES Flexibase

65329652

Analogs

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Popular Name: N-ethyl-3-isobutyl-6-methyl-N-(m-tolyl)-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-ethyl-3-isobutyl-6-methyl-N-(m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.38	10.07	-21.17	0	6	0	68	367.449	5	↓ MOL2 SDF SMILES Flexibase

65329653

Analogs

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Popular Name: N-(2,5-dimethylphenyl)-N-ethyl-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2,5-dimethylphenyl)-N-ethyl-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.78	10.43	-22.34	0	6	0	68	381.476	5	↓ MOL2 SDF SMILES Flexibase

65329665

Analogs

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Popular Name: 3-isobutyl-N,6-dimethyl-4-oxo-N-phenyl-furo[2,3-d]pyrimidine-5-carboxamide 3-isobutyl-N,6-dimethyl-4-oxo-N-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.58	8.77	-22.39	0	6	0	68	339.395	4	↓ MOL2 SDF SMILES Flexibase

65329667

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.86	8.62	-25.33	1	8	0	103	397.431	7	↓ MOL2 SDF SMILES Flexibase

65329668

Analogs

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Popular Name: N-(2-chloro-4-methyl-phenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-chloro-4-methyl-phenyl)-3-i…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.39	7.91	-18.79	1	6	0	77	373.84	4	↓ MOL2 SDF SMILES Flexibase

65329673

Analogs

7001390

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Popular Name: N-(3-ethylphenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(3-ethylphenyl)-3-isobutyl-6-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.22	8.06	-19.65	1	6	0	77	353.422	5	↓ MOL2 SDF SMILES Flexibase

65329676

Analogs

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Popular Name: 3-isobutyl-6-methyl-N-(3-methylsulfanylphenyl)-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide 3-isobutyl-6-methyl-N-(3-methyls…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.74	7.67	-21.88	1	6	0	77	371.462	5	↓ MOL2 SDF SMILES Flexibase

65329686

Analogs

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Popular Name: 3-isobutyl-6-methyl-N-(o-tolyl)-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide 3-isobutyl-6-methyl-N-(o-tolyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	7.95	-21.15	1	6	0	77	339.395	4	↓ MOL2 SDF SMILES Flexibase

65329687

Analogs

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Popular Name: N-(2-ethylphenyl)-3-isobutyl-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide N-(2-ethylphenyl)-3-isobutyl-6-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.20	8.31	-20.55	1	6	0	77	353.422	5	↓ MOL2 SDF SMILES Flexibase

65329690

Analogs

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Popular Name: 3-isobutyl-N-(4-methoxyphenyl)-6-methyl-4-oxo-furo[2,3-d]pyrimidine-5-carboxamide 3-isobutyl-N-(4-methoxyphenyl)-6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.39	5.95	-20.97	1	7	0	86	355.394	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

ring.id = 87764
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 87764 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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<div id="zinc-link"></div>
<script type="text/javascript" src="//zinc12.docking.org/js/embed.js"></script>
<script type="text/javascript">
    window.zinc.embed('zinc-link', {
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