UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: 3-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]phenol 3-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 290 0.46 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 290 0.46 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 290 0.46 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.16 6.57 -26.33 2 4 1 49 290.412 3 ↓
Lo Low (pH 4.5-6) 0.16 6.68 -94.19 3 4 2 50 291.42 3 ↓

Analogs

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Popular Name: methyl methyl

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 230 0.40 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 230 0.40 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 230 0.40 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.84 9.83 -29.94 1 5 1 55 332.449 5 ↓
Lo Low (pH 4.5-6) 0.84 9.96 -104.63 2 5 2 56 333.457 5 ↓

Analogs

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Popular Name: 4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]benzenesulfonamide 4-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 150 0.42 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 150 0.42 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 150 0.42 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.64 4.38 -34.62 3 6 1 89 353.493 4 ↓
Hi High (pH 8-9.5) 4.03 3.3 -11.29 2 6 0 90 352.485 3 ↓
Lo Low (pH 4.5-6) -0.64 4.49 -109.4 4 6 2 90 354.501 4 ↓

Analogs

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Popular Name: methyl methyl

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 140 0.42 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 140 0.42 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 140 0.42 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.81 10.06 -29.78 1 5 1 55 332.449 5 ↓
Lo Low (pH 4.5-6) 0.81 10.18 -99 2 5 2 56 333.457 5 ↓

Analogs

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Popular Name: 4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]-N-(2-dimethylaminoethyl)-N-methyl-benzamid 4-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 470 0.32 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 470 0.32 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 470 0.32 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.34 11.35 -74.31 2 6 2 54 403.596 7 ↓
Lo Low (pH 4.5-6) -0.34 11.48 -158.28 3 6 3 55 404.604 7 ↓

Analogs

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Popular Name: N-cyclohexyl-3-methyl-5-(4-methylsulfonylphenyl)-1,3,4-thiadiazol-2-imine N-cyclohexyl-3-methyl-5-(4-methy…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 130 0.42 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 130 0.42 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 130 0.42 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.46 6.96 -34.7 1 5 1 63 352.505 4 ↓
Lo Low (pH 4.5-6) -0.46 7.08 -108.16 2 5 2 64 353.513 4 ↓

Analogs

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Popular Name: 5-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]-2-methoxy-benzene-1,3-diol 5-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 60 0.44 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 60 0.44 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 60 0.44 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.32 4.45 -31.05 3 6 1 78 336.437 4 ↓
Hi High (pH 8-9.5) -0.32 5.35 -46.61 2 6 0 81 335.429 4 ↓
Lo Low (pH 4.5-6) -0.32 4.56 -102.62 4 6 2 80 337.445 4 ↓

Analogs

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Popular Name: 4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]-2-hydroxy-benzamide 4-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 120 0.42 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 120 0.42 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 120 0.42 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.05 4.57 -36.2 4 6 1 92 333.437 4 ↓
Hi High (pH 8-9.5) -0.05 5.58 -59 3 6 0 95 332.429 4 ↓
Lo Low (pH 4.5-6) -0.05 4.7 -109.52 5 6 2 93 334.445 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]-2-methoxy-benzamide 4-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 470 0.37 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 470 0.37 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 470 0.37 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.02 6.59 -37.46 3 6 1 81 347.464 5 ↓
Lo Low (pH 4.5-6) 0.02 6.72 -112.35 4 6 2 82 348.472 5 ↓

Analogs

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Popular Name: 4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]benzoic 4-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 550 0.40 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 550 0.40 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 550 0.40 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.58 9.74 -57.11 1 5 0 69 317.414 4 ↓
Lo Low (pH 4.5-6) 0.58 9.87 -115.76 2 5 1 70 318.422 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]-2-methyl-benzamide 4-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 930 0.37 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 930 0.37 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 930 0.37 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.14 6.66 -32.87 3 5 1 72 331.465 4 ↓
Lo Low (pH 4.5-6) -0.14 6.8 -106.28 4 5 2 73 332.473 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]benzenesulfonamide 3-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 200 0.41 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 200 0.41 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 200 0.41 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.66 4.39 -34.44 3 6 1 89 353.493 4 ↓
Hi High (pH 8-9.5) 4.00 3.3 -12.5 2 6 0 90 352.485 3 ↓
Lo Low (pH 4.5-6) -0.66 4.5 -106.11 4 6 2 90 354.501 4 ↓

Analogs

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Popular Name: 4-[[5-(4-chlorophenyl)-3-methyl-1,3,4-thiadiazol-2-ylidene]amino]cyclohexanamine 4-[[5-(4-chlorophenyl)-3-methyl-…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 5900 0.35 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 5900 0.35 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.77 7.48 -93.4 4 4 2 56 324.881 3 ↓

Analogs

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Popular Name: 3-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]benzamide 3-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 90 0.45 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 90 0.45 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 90 0.45 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.54 6.2 -31.95 3 5 1 72 317.438 4 ↓
Lo Low (pH 4.5-6) -0.54 6.31 -98.7 4 5 2 73 318.446 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 3-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]benzoic 3-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 870 0.39 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 870 0.39 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 870 0.39 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.55 9.98 -57.09 1 5 0 69 317.414 4 ↓
Lo Low (pH 4.5-6) 0.55 10.09 -105.78 2 5 1 70 318.422 4 ↓

Analogs

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Popular Name: methyl methyl

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 7500 0.31 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 7500 0.31 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.45 9.89 -25.13 1 5 1 55 332.449 5 ↓
Lo Low (pH 4.5-6) 0.45 9.7 -84.85 2 5 2 56 333.457 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-amino-4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]benzamide 2-amino-4-[(5Z)-5-cyclohexylimin…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 80 0.43 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 80 0.43 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 80 0.43 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.10 4.19 -31.49 5 6 1 98 332.453 4 ↓
Lo Low (pH 4.5-6) -1.10 4.32 -103.53 6 6 2 99 333.461 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[(5Z)-5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl]-N-(2-dimethylaminoethyl)benzamide 4-[(5Z)-5-cyclohexylimino-4-meth…

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Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PDE7A-1-E Phosphodiesterase 7A (cluster #1 Of 1), Eukaryotic Eukaryotes 60 0.37 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 60 0.37 Binding ≤ 1μM
PDE7A_HUMAN Q13946 Phosphodiesterase 7A, Human 60 0.37 Binding ≤ 10μM

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.11 9.6 -76.92 3 6 2 62 389.569 7 ↓
Lo Low (pH 4.5-6) -0.11 9.73 -162.66 4 6 3 64 390.577 7 ↓

Parameters Provided:

ring.id = 89706
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 89706 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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