UCSF
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Analogs

9562182
9562182

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Popular Name: 2-[(4S)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]-N-(4-iodo-2-methyl-phenyl)acetamide 2-[(4S)-2,5-dioxospiro[imidazoli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 8.31 -18.54 2 6 0 79 475.286 3 ↓

Analogs

36637073
36637073

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Popular Name: 2-[(4S)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-iodo-4-methyl-phenyl)acetamide 2-[(4S)-2,5-dioxospiro[imidazoli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 8.06 -13.35 2 6 0 79 475.286 3 ↓

Analogs

36637071
36637071

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Popular Name: 2-[(4R)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-iodo-4-methyl-phenyl)acetamide 2-[(4R)-2,5-dioxospiro[imidazoli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 8.07 -17.98 2 6 0 79 475.286 3 ↓

Analogs

36637077
36637077

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Popular Name: 2-[(4S)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-propoxyphenyl)acetamide 2-[(4S)-2,5-dioxospiro[imidazoli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.15 7.59 -14.05 2 7 0 88 393.443 6 ↓

Analogs

36637075
36637075

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Popular Name: 2-[(4R)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-propoxyphenyl)acetamide 2-[(4R)-2,5-dioxospiro[imidazoli…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.15 7.59 -15.99 2 7 0 88 393.443 6 ↓

Analogs

13012380
13012380

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Popular Name: N-[4-[[2-[(4R)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetyl]amino]phenyl]-3-methyl-butanami N-[4-[[2-[(4R)-2,5-dioxospiro[im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7.5 -18.66 3 8 0 108 434.496 6 ↓

Analogs

13012379
13012379

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Popular Name: N-[4-[[2-[(4S)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetyl]amino]phenyl]-3-methyl-butanami N-[4-[[2-[(4S)-2,5-dioxospiro[im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7.51 -20.02 3 8 0 108 434.496 6 ↓

Analogs

36875862
36875862
7278847
7278847
7278850
7278850
7278838
7278838

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Popular Name: 3-[[2-[(4S)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetyl]amino]benzamide 3-[[2-[(4S)-2,5-dioxospiro[imida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 3.21 -28.77 4 8 0 122 378.388 4 ↓

Analogs

36875861
36875861
7278847
7278847
7278850
7278850

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Popular Name: 3-[[2-[(4R)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetyl]amino]benzamide 3-[[2-[(4R)-2,5-dioxospiro[imida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 3.22 -25.97 4 8 0 122 378.388 4 ↓

Analogs

36875880
36875880

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Popular Name: N-(3-chloro-4-cyano-phenyl)-2-[(4S)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(3-chloro-4-cyano-phenyl)-2-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.25 -17.32 2 7 0 102 394.818 3 ↓

Analogs

36875879
36875879

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Popular Name: N-(3-chloro-4-cyano-phenyl)-2-[(4R)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(3-chloro-4-cyano-phenyl)-2-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.25 -15.78 2 7 0 102 394.818 3 ↓

Analogs

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Popular Name: N-(5-chloro-2,4-dimethoxy-phenyl)-2-[(4R)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(5-chloro-2,4-dimethoxy-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 5.73 -21.28 2 8 0 97 429.86 5 ↓

Analogs

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Popular Name: N-(5-chloro-2,4-dimethoxy-phenyl)-2-[(4S)-2,5-dioxospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(5-chloro-2,4-dimethoxy-phenyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.91 5.72 -22.13 2 8 0 97 429.86 5 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.79 7.99 -27.65 2 8 0 105 407.426 6 ↓

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.79 7.97 -27.69 2 8 0 105 407.426 6 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2,4-dimethoxyphenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 5.15 -16.33 2 8 0 97 395.415 5 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2,4-dimethoxyphenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 5.15 -16.36 2 8 0 97 395.415 5 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-fluorophenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 6.5 -17.39 2 6 0 79 353.353 3 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-fluorophenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 6.5 -19.7 2 6 0 79 353.353 3 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-iodophenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.30 -2.84 -13.76 2 6 0 78 461.259 3 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-iodophenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.30 -2.84 -13.71 2 6 0 78 461.259 3 ↓

Analogs

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Popular Name: N-(4-chloro-2-methyl-phenyl)-2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(4-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 -1.85 -15.77 2 6 0 78 383.835 3 ↓

Analogs

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Popular Name: N-(4-chloro-2-methyl-phenyl)-2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(4-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 -1.88 -15.68 2 6 0 78 383.835 3 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(5-fluoro-2-methyl-phenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 -0.99 -18.87 2 6 0 78 367.38 3 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(5-fluoro-2-methyl-phenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 -0.99 -18.64 2 6 0 78 367.38 3 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-fluoro-4-methyl-phenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 7.15 -15.23 2 6 0 79 367.38 3 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-fluoro-4-methyl-phenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 7.14 -15.14 2 6 0 79 367.38 3 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-methyl-3-nitro-phenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 -1.31 -16.53 2 9 0 124 394.387 4 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-methyl-3-nitro-phenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 -1.31 -16.58 2 9 0 124 394.387 4 ↓

Analogs

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Popular Name: N-(2-acetylphenyl)-2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(2-acetylphenyl)-2-[(4R)-2,5-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.11 -1.42 -17.91 2 7 0 95 377.4 4 ↓

Analogs

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Popular Name: N-(2-acetylphenyl)-2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(2-acetylphenyl)-2-[(4S)-2,5-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.11 -1.42 -17.76 2 7 0 95 377.4 4 ↓

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-ethyl-6-methyl-phenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 8.79 -15.04 2 6 0 79 377.444 4 ↓

Analogs

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-ethyl-6-methyl-phenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 8.9 -16.4 2 6 0 79 377.444 4 ↓

Analogs

8890445
8890445
8890447
8890447

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-isopropyl-N-phenyl-acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 -0.32 -14.62 1 6 0 69 377.444 4 ↓

Analogs

8890445
8890445
8890447
8890447

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-isopropyl-N-phenyl-acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 8.86 -14.66 1 6 0 70 377.444 4 ↓

Analogs

21337260
21337260

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-methyl-N-phenyl-acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 8.12 -17.88 1 6 0 70 349.39 3 ↓

Analogs

21337260
21337260

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-methyl-N-phenyl-acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 8.12 -15.54 1 6 0 70 349.39 3 ↓

Analogs

3378521
3378521
3378523
3378523

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3,4-dimethylphenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7.65 -16.77 2 6 0 79 363.417 3 ↓

Analogs

3378521
3378521
3378523
3378523

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Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3,4-dimethylphenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7.65 -16.72 2 6 0 79 363.417 3 ↓

Analogs

31817854
31817854
31817860
31817860

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-methoxyphenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 5.73 -17.17 2 7 0 88 365.389 4 ↓

Analogs

31817854
31817854
31817860
31817860

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(3-methoxyphenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 5.72 -15.24 2 7 0 88 365.389 4 ↓

Analogs

14429107
14429107
14429108
14429108
22059441
22059441
22059445
22059445
26380333
26380333

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(m-tolyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 -1.96 -16.63 2 6 0 78 349.39 3 ↓

Analogs

14429107
14429107
14429108
14429108
22059441
22059441
22059445
22059445
26380333
26380333

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(m-tolyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 -1.97 -17.07 2 6 0 78 349.39 3 ↓

Analogs

8890602
8890602
8890603
8890603
44701189
44701189

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-methoxy-5-methyl-phenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 6.52 -16.34 2 7 0 88 379.416 4 ↓

Analogs

8890602
8890602
8890603
8890603
44701189
44701189

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2-methoxy-5-methyl-phenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 6.52 -16.43 2 7 0 88 379.416 4 ↓

Analogs

8312431
8312431
8312434
8312434
8889943
8889943
8889945
8889945
16617736
16617736

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2,6-dimethylphenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.13 -1.44 -14.07 2 6 0 78 363.417 3 ↓

Analogs

8312431
8312431
8312434
8312434

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2,6-dimethylphenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.13 -1.44 -15.49 2 6 0 78 363.417 3 ↓

Analogs

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Popular Name: 2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2,5-dimethoxyphenyl)acetamide 2-[(4R)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 -2.13 -19.17 2 8 0 96 395.415 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[(4S)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]-N-(2,5-dimethoxyphenyl)acetamide 2-[(4S)-2,5-diketospiro[imidazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 -2.14 -19.24 2 8 0 96 395.415 5 ↓

Analogs

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Popular Name: N-(3-bromophenyl)-2-[(4R)-2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl]acetamide N-(3-bromophenyl)-2-[(4R)-2,5-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 -3.03 -17.65 2 6 0 78 414.259 3 ↓

Parameters Provided:

ring.id = 94436
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 94436 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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