UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

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Popular Name: N-(3-fluorophenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(3-fluorophenyl)-2-[2-(hydroxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.30 -0.73 -37.3 2 6 0 81 306.293 5 ↓

Analogs

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Popular Name: N-(4-fluorophenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(4-fluorophenyl)-2-[2-(hydroxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.32 -0.74 -35.32 2 6 0 81 306.293 5 ↓

Analogs

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Popular Name: N-(3-chlorophenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(3-chlorophenyl)-2-[2-(hydroxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.81 -1.62 -35.92 2 6 0 81 322.748 5 ↓

Analogs

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Popular Name: N-(4-chlorophenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(4-chlorophenyl)-2-[2-(hydroxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.83 -1.62 -34.5 2 6 0 81 322.748 5 ↓

Analogs

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Popular Name: N-(2,4-difluorophenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(2,4-difluorophenyl)-2-[2-(hyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.41 0.03 -31.17 2 6 0 81 324.283 5 ↓

Analogs

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Popular Name: N-(3,4-dichlorophenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(3,4-dichlorophenyl)-2-[2-(hyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 -1.75 -37.29 2 6 0 81 357.193 5 ↓

Analogs

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Popular Name: N-(5-chloro-2-methoxy-phenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(5-chloro-2-methoxy-phenyl)-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.82 -1.49 -32.91 2 7 0 90 352.774 6 ↓

Analogs

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Popular Name: N-(2,5-dimethoxyphenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(2,5-dimethoxyphenyl)-2-[2-(hy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 -1.34 -34.33 2 8 0 99 348.355 7 ↓

Analogs

71282958
71282958

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Popular Name: N-(3,4-dimethoxyphenyl)-2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetamide N-(3,4-dimethoxyphenyl)-2-[2-(hy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.20 -1.15 -36.89 2 8 0 99 348.355 7 ↓

Analogs

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Popular Name: 2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]-N-[2-(trifluoromethyl)phenyl]acetamide 2-[2-(hydroxymethyl)-5-methoxy-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.00 0.96 -29.33 2 6 0 81 356.3 6 ↓

Analogs

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Popular Name: 2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]-N-[3-(trifluoromethyl)phenyl]acetamide 2-[2-(hydroxymethyl)-5-methoxy-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.03 0.69 -33.32 2 6 0 81 356.3 6 ↓

Analogs

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Popular Name: 2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]-N-[4-(trifluoromethyl)phenyl]acetamide 2-[2-(hydroxymethyl)-5-methoxy-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 0.69 -35.71 2 6 0 81 356.3 6 ↓

Analogs

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Popular Name: 2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]-N-[4-(trifluoromethoxy)phenyl]acetamide 2-[2-(hydroxymethyl)-5-methoxy-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.13 0.03 -35.66 2 7 0 90 372.299 7 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.33 -0.35 -37.64 2 8 0 107 346.339 7 ↓

Analogs

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Popular Name: 4-[[2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]acetyl]amino]benzamide 4-[[2-[2-(hydroxymethyl)-5-metho…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.02 -4.19 -38.76 4 8 0 124 331.328 6 ↓

Analogs

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Popular Name: 2-[2-(hydroxymethyl)-5-methoxy-4-oxo-1-pyridyl]-N-methyl-N-phenyl-acetamide 2-[2-(hydroxymethyl)-5-methoxy-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.40 0.11 -32.94 1 6 0 72 302.33 5 ↓

Parameters Provided:

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