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ZINC Item

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12232783

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-acetamidophenyl)-2-(2-methyl-7-phenyl-thiazolo[4,5-d]pyridazin-4-yl)sulfanyl-acetamide N-(3-acetamidophenyl)-2-(2-methy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.07	-3.05	-20.79	2	7	0	97	449.561	6	↓ MOL2 SDF SMILES Flexibase

12232788

Analogs

13973384
14007748

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-acetamidophenyl)-2-(2-methyl-7-phenyl-thiazolo[4,5-d]pyridazin-4-yl)sulfanyl-acetamide N-(4-acetamidophenyl)-2-(2-methy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	-3.03	-20.63	2	7	0	97	449.561	6	↓ MOL2 SDF SMILES Flexibase

12232816

Analogs

14007857

Draw Identity 99% 90% 80% 70%

Popular Name: 4-[[2-(2-methyl-7-phenyl-thiazolo[4,5-d]pyridazin-4-yl)sulfanylacetyl]amino]benzamide 4-[[2-(2-methyl-7-phenyl-thiazol…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.69	-4.65	-23.3	3	7	0	111	435.534	6	↓ MOL2 SDF SMILES Flexibase

14007026

Analogs

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Popular Name: 2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-phenyl-acetamide 2-[7-(4-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.93	7.86	-15.97	1	6	0	77	422.535	6	↓ MOL2 SDF SMILES Flexibase

14007028

Analogs

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Popular Name: 2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(o-tolyl)acetamide 2-[7-(4-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.33	8.75	-15.9	1	6	0	77	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007030

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(m-tolyl)acetamide 2-[7-(4-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.35	8.53	-15.96	1	6	0	77	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007032

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(p-tolyl)acetamide 2-[7-(4-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.38	8.54	-16.04	1	6	0	77	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007034

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,3-dimethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,3-dimethylphenyl)-2-[7-(4-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.73	9.27	-16.04	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007036

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,5-dimethylphenyl)-2-[7-(4-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	9.38	-16.03	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007039

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,4-dimethylphenyl)-2-[7-(4-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	9.42	-16.03	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007041

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3,5-dimethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(3,5-dimethylphenyl)-2-[7-(4-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	9.2	-16.14	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007043

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-ethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(4-ethylphenyl)-2-[7-(4-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.84	9.3	-15.94	1	6	0	77	450.589	7	↓ MOL2 SDF SMILES Flexibase

14007045

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-fluorophenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2-fluorophenyl)-2-[7-(4-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.04	7.96	-14.94	1	6	0	77	440.525	6	↓ MOL2 SDF SMILES Flexibase

14007047

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-fluorophenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(3-fluorophenyl)-2-[7-(4-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.07	7.93	-18.25	1	6	0	77	440.525	6	↓ MOL2 SDF SMILES Flexibase

14007049

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-fluorophenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(4-fluorophenyl)-2-[7-(4-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.09	7.93	-16.04	1	6	0	77	440.525	6	↓ MOL2 SDF SMILES Flexibase

14007155

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-methyl-N-phenyl-acetamide 2-[7-(4-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.17	9.62	-16.46	0	6	0	68	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007177

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-ethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2-ethylphenyl)-2-[7-(4-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.80	9.53	-15.39	1	6	0	77	450.589	7	↓ MOL2 SDF SMILES Flexibase

14007179

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,6-dimethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,6-dimethylphenyl)-2-[7-(4-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.79	9.71	-16.13	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007181

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-ethylphenyl)-2-[7-(4-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(3-ethylphenyl)-2-[7-(4-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.82	9.3	-15.67	1	6	0	77	450.589	7	↓ MOL2 SDF SMILES Flexibase

14007217

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-phenyl-acetamide 2-[7-(3-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.90	7.86	-17.71	1	6	0	77	422.535	6	↓ MOL2 SDF SMILES Flexibase

14007219

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(o-tolyl)acetamide 2-[7-(3-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.31	8.75	-17.6	1	6	0	77	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007221

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(m-tolyl)acetamide 2-[7-(3-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.33	8.54	-17.6	1	6	0	77	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007223

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(p-tolyl)acetamide 2-[7-(3-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.35	8.54	-17.79	1	6	0	77	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007225

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,3-dimethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,3-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.71	9.27	-17.72	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007227

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,5-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.73	9.38	-17.7	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007230

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,4-dimethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,4-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.73	9.42	-17.7	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007232

Analogs

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Popular Name: N-(3,5-dimethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(3,5-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.73	9.2	-17.87	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007234

Analogs

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Popular Name: N-(4-ethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(4-ethylphenyl)-2-[7-(3-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.82	9.3	-17.63	1	6	0	77	450.589	7	↓ MOL2 SDF SMILES Flexibase

14007236

Analogs

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Popular Name: N-(2-fluorophenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2-fluorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.02	7.96	-16.76	1	6	0	77	440.525	6	↓ MOL2 SDF SMILES Flexibase

14007238

Analogs

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Popular Name: N-(3-fluorophenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(3-fluorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.04	7.93	-19.83	1	6	0	77	440.525	6	↓ MOL2 SDF SMILES Flexibase

14007241

Analogs

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Popular Name: N-(4-fluorophenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(4-fluorophenyl)-2-[7-(3-metho…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.07	7.93	-17.68	1	6	0	77	440.525	6	↓ MOL2 SDF SMILES Flexibase

14007383

Analogs

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Popular Name: 2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-methyl-N-phenyl-acetamide 2-[7-(3-methoxyphenyl)-2-methyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.15	9.62	-18.07	0	6	0	68	436.562	6	↓ MOL2 SDF SMILES Flexibase

14007412

Analogs

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Popular Name: N-(2-ethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2-ethylphenyl)-2-[7-(3-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	9.53	-17.11	1	6	0	77	450.589	7	↓ MOL2 SDF SMILES Flexibase

14007414

Analogs

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Popular Name: N-(2,6-dimethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetam N-(2,6-dimethylphenyl)-2-[7-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.77	9.71	-17.78	1	6	0	77	450.589	6	↓ MOL2 SDF SMILES Flexibase

14007416

Analogs

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Popular Name: N-(3-ethylphenyl)-2-[7-(3-methoxyphenyl)-2-methyl-thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(3-ethylphenyl)-2-[7-(3-methox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.80	9.3	-17.37	1	6	0	77	450.589	7	↓ MOL2 SDF SMILES Flexibase

14007748

Analogs

12232788

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Popular Name: 2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-phenyl-acetamide 2-[2-methyl-7-(p-tolyl)thiazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.32	9.24	-15.69	1	5	0	68	406.536	5	↓ MOL2 SDF SMILES Flexibase

14007750

Analogs

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Popular Name: 2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(o-tolyl)acetamide 2-[2-methyl-7-(p-tolyl)thiazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.72	10.09	-15.55	1	5	0	68	420.563	5	↓ MOL2 SDF SMILES Flexibase

14007753

Analogs

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Popular Name: 2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(m-tolyl)acetamide 2-[2-methyl-7-(p-tolyl)thiazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	9.91	-15.84	1	5	0	68	420.563	5	↓ MOL2 SDF SMILES Flexibase

14007755

Analogs

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Popular Name: 2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(p-tolyl)acetamide 2-[2-methyl-7-(p-tolyl)thiazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	9.92	-15.74	1	5	0	68	420.563	5	↓ MOL2 SDF SMILES Flexibase

14007758

Analogs

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Popular Name: N-(2,3-dimethylphenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2,3-dimethylphenyl)-2-[2-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.12	10.65	-15.75	1	5	0	68	434.59	5	↓ MOL2 SDF SMILES Flexibase

14007761

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dimethylphenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2,5-dimethylphenyl)-2-[2-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	10.76	-15.81	1	5	0	68	434.59	5	↓ MOL2 SDF SMILES Flexibase

14007764

Analogs

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Popular Name: N-(2,4-dimethylphenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2,4-dimethylphenyl)-2-[2-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	10.76	-15.66	1	5	0	68	434.59	5	↓ MOL2 SDF SMILES Flexibase

14007767

Analogs

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Popular Name: N-(3,5-dimethylphenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(3,5-dimethylphenyl)-2-[2-meth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	10.58	-15.79	1	5	0	68	434.59	5	↓ MOL2 SDF SMILES Flexibase

14007770

Analogs

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Popular Name: 2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-N-(2,4,6-trimethylphenyl)acetamide 2-[2-methyl-7-(p-tolyl)thiazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.59	11.51	-15.34	1	5	0	68	448.617	5	↓ MOL2 SDF SMILES Flexibase

14007774

Analogs

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Popular Name: N-(4-ethylphenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(4-ethylphenyl)-2-[2-methyl-7-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.24	10.68	-15.58	1	5	0	68	434.59	6	↓ MOL2 SDF SMILES Flexibase

14007777

Analogs

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Popular Name: N-(2-fluorophenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(2-fluorophenyl)-2-[2-methyl-7…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.44	9.34	-14.66	1	5	0	68	424.526	5	↓ MOL2 SDF SMILES Flexibase

14007780

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-fluorophenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(3-fluorophenyl)-2-[2-methyl-7…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.46	9.31	-17.85	1	5	0	68	424.526	5	↓ MOL2 SDF SMILES Flexibase

14007783

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-fluorophenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(4-fluorophenyl)-2-[2-methyl-7…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.49	9.31	-15.72	1	5	0	68	424.526	5	↓ MOL2 SDF SMILES Flexibase

14007789

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(3-chlorophenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(3-chlorophenyl)-2-[2-methyl-7…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.97	9.76	-16.86	1	5	0	68	440.981	5	↓ MOL2 SDF SMILES Flexibase

14007792

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(4-chlorophenyl)-2-[2-methyl-7-(p-tolyl)thiazolo[4,5-d]pyridazin-4-yl]sulfanyl-acetamide N-(4-chlorophenyl)-2-[2-methyl-7…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.00	9.76	-15.19	1	5	0	68	440.981	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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