UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

12236230
12236230

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Popular Name: N-(4-fluorophenyl)-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-fluorophenyl)-2-[(3R)-5-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.53 -1.2 -11.28 1 5 0 64 305.334 3 ↓

Analogs

12236228
12236228

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Popular Name: N-(4-fluorophenyl)-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-fluorophenyl)-2-[(3S)-5-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.53 -1.23 -11.71 1 5 0 64 305.334 3 ↓

Analogs

12236234
12236234

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Popular Name: N-(2-chlorophenyl)-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2-chlorophenyl)-2-[(3R)-5-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 -1.91 -9.48 1 5 0 64 321.789 3 ↓

Analogs

12236233
12236233

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Popular Name: N-(2-chlorophenyl)-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2-chlorophenyl)-2-[(3S)-5-oxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 -1.93 -10.4 1 5 0 64 321.789 3 ↓

Analogs

12236244
12236244

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Popular Name: N-(3,4-dichlorophenyl)-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-dichlorophenyl)-2-[(3R)-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.65 -2.21 -12.32 1 5 0 64 356.234 3 ↓

Analogs

12236242
12236242

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Popular Name: N-(3,4-dichlorophenyl)-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-dichlorophenyl)-2-[(3S)-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.65 -2.25 -10.6 1 5 0 64 356.234 3 ↓

Analogs

12236249
12236249
14031249
14031249
14031250
14031250

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Popular Name: N-(2,3-dimethylphenyl)-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,3-dimethylphenyl)-2-[(3R)-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.17 -1.08 -10.91 1 5 0 64 315.398 3 ↓

Analogs

14031249
14031249
14031250
14031250
12236246
12236246

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Popular Name: N-(2,3-dimethylphenyl)-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,3-dimethylphenyl)-2-[(3S)-5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.17 -1.1 -11.15 1 5 0 64 315.398 3 ↓

Analogs

12236253
12236253
14031335
14031335
14031337
14031337

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Popular Name: N-(3,4-dimethoxyphenyl)-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-dimethoxyphenyl)-2-[(3R)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.01 -1.6 -13.8 1 7 0 82 347.396 5 ↓

Analogs

14031335
14031335
14031337
14031337
12236252
12236252

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Popular Name: N-(3,4-dimethoxyphenyl)-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-dimethoxyphenyl)-2-[(3S)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.01 -1.63 -14.15 1 7 0 82 347.396 5 ↓

Analogs

12236259
12236259

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Popular Name: N-(2,5-dimethoxyphenyl)-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,5-dimethoxyphenyl)-2-[(3R)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.41 -1.8 -13.04 1 7 0 82 347.396 5 ↓

Analogs

12236256
12236256

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Popular Name: N-(2,5-dimethoxyphenyl)-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,5-dimethoxyphenyl)-2-[(3S)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.41 -1.82 -13.33 1 7 0 82 347.396 5 ↓

Analogs

12236273
12236273

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Popular Name: N-[3,5-bis(trifluoromethyl)phenyl]-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-[3,5-bis(trifluoromethyl)pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 2.41 -11.52 1 5 0 64 423.338 5 ↓

Analogs

12236268
12236268

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Popular Name: N-[3,5-bis(trifluoromethyl)phenyl]-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-[3,5-bis(trifluoromethyl)pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 2.37 -11.99 1 5 0 64 423.338 5 ↓

Analogs

12236279
12236279

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 -1.77 -12.11 1 5 0 64 335.816 3 ↓

Analogs

12236275
12236275

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 -1.8 -10.26 1 5 0 64 335.816 3 ↓

Analogs

12236329
12236329

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Popular Name: 2-[(3R)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]-N-(2,3,4-trifluorophenyl)acetamide 2-[(3R)-5-oxo-2,3-dihydrothiazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.72 0.31 -10.46 1 5 0 64 341.314 3 ↓

Analogs

12236327
12236327

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Popular Name: 2-[(3S)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]-N-(2,3,4-trifluorophenyl)acetamide 2-[(3S)-5-oxo-2,3-dihydrothiazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.72 0.28 -10.63 1 5 0 64 341.314 3 ↓

Analogs

12236448
12236448
14031611
14031611
14031612
14031612
14031617
14031617
14031619
14031619

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Popular Name: N-(4-isopropylphenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-isopropylphenyl)-2-[(3R)-7-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 -1.01 -10.59 1 5 0 64 343.452 4 ↓

Analogs

14031611
14031611
14031612
14031612
14031617
14031617
14031619
14031619
12236445
12236445

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Popular Name: N-(4-isopropylphenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-isopropylphenyl)-2-[(3S)-7-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 -1.01 -10.87 1 5 0 64 343.452 4 ↓

Analogs

12236453
12236453
14031710
14031710
14031712
14031712

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Popular Name: N-(3-chlorophenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3-chlorophenyl)-2-[(3S)-7-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 -1.94 -11.83 1 5 0 64 335.816 3 ↓

Analogs

14031710
14031710
14031712
14031712
12236450
12236450

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Popular Name: N-(3-chlorophenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3-chlorophenyl)-2-[(3R)-7-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 -1.94 -9.62 1 5 0 64 335.816 3 ↓

Analogs

12236458
12236458

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Popular Name: 2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetam 2-[(3S)-7-methyl-5-oxo-2,3-dihyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 0.35 -11.83 1 5 0 64 369.368 4 ↓

Analogs

12236455
12236455

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Popular Name: 2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetam 2-[(3R)-7-methyl-5-oxo-2,3-dihyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 0.35 -11.59 1 5 0 64 369.368 4 ↓

Analogs

12236463
12236463

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Popular Name: N-(3-methoxyphenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3-methoxyphenyl)-2-[(3R)-7-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 -1.77 -10.99 1 6 0 73 331.397 4 ↓

Analogs

12236461
12236461

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Popular Name: N-(3-methoxyphenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3-methoxyphenyl)-2-[(3S)-7-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 -1.79 -12.91 1 6 0 73 331.397 4 ↓

Analogs

12236473
12236473

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Popular Name: N-(2,4-difluorophenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,4-difluorophenyl)-2-[(3S)-7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 -0.28 -10.46 1 5 0 64 337.351 3 ↓

Analogs

12236471
12236471

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Popular Name: N-(2,4-difluorophenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,4-difluorophenyl)-2-[(3R)-7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 -0.28 -8.98 1 5 0 64 337.351 3 ↓

Analogs

12236479
12236479
14031606
14031606
14031607
14031607

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Popular Name: N-(2,6-dimethylphenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,6-dimethylphenyl)-2-[(3S)-7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.67 -0.97 -10.71 1 5 0 64 329.425 3 ↓

Analogs

14031606
14031606
14031607
14031607
12236476
12236476

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Popular Name: N-(2,6-dimethylphenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(2,6-dimethylphenyl)-2-[(3R)-7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.67 -0.92 -10.57 1 5 0 64 329.425 3 ↓

Analogs

12236484
12236484
14031609
14031609
14031610
14031610

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Popular Name: N-(3,5-dimethylphenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,5-dimethylphenyl)-2-[(3R)-7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.63 -1.16 -11 1 5 0 64 329.425 3 ↓

Analogs

14031609
14031609
14031610
14031610
12236481
12236481

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Popular Name: N-(3,5-dimethylphenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,5-dimethylphenyl)-2-[(3S)-7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.63 -1.17 -11.19 1 5 0 64 329.425 3 ↓

Analogs

12236488
12236488

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetami N-(3-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.86 -1.64 -12.58 1 5 0 64 349.843 3 ↓

Analogs

12236486
12236486

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Popular Name: N-(3-chloro-4-methyl-phenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetami N-(3-chloro-4-methyl-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.86 -1.63 -11.7 1 5 0 64 349.843 3 ↓

Analogs

12236492
12236492

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Popular Name: N-[4-fluoro-3-(trifluoromethyl)phenyl]-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3- N-[4-fluoro-3-(trifluoromethyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 1.05 -12.39 1 5 0 64 387.358 4 ↓

Analogs

12236491
12236491

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Popular Name: N-[4-fluoro-3-(trifluoromethyl)phenyl]-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3- N-[4-fluoro-3-(trifluoromethyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 1.06 -11.04 1 5 0 64 387.358 4 ↓

Analogs

12236496
12236496

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Popular Name: N-(2-methoxy-5-methyl-phenyl)-2-[(3R)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetam N-(2-methoxy-5-methyl-phenyl)-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 -1.33 -11.01 1 6 0 73 345.424 4 ↓

Analogs

12236495
12236495

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Popular Name: N-(2-methoxy-5-methyl-phenyl)-2-[(3S)-7-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetam N-(2-methoxy-5-methyl-phenyl)-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 -1.32 -11 1 6 0 73 345.424 4 ↓

Analogs

12236589
12236589
14032106
14032106
14032108
14032108
14032114
14032114
14032116
14032116

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Popular Name: N-(4-isopropylphenyl)-2-[(3R)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-isopropylphenyl)-2-[(3R)-6-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 -0.83 -10.42 1 5 0 64 343.452 4 ↓

Analogs

14032106
14032106
14032108
14032108
14032114
14032114
14032116
14032116
12236586
12236586

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Popular Name: N-(4-isopropylphenyl)-2-[(3S)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-isopropylphenyl)-2-[(3S)-6-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 -0.87 -10.7 1 5 0 64 343.452 4 ↓

Analogs

12236591
12236591

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Popular Name: N-(4-methoxyphenyl)-2-[(3R)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-methoxyphenyl)-2-[(3R)-6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 -1.62 -11.64 1 6 0 73 331.397 4 ↓

Analogs

12236590
12236590

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Popular Name: N-(4-methoxyphenyl)-2-[(3S)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(4-methoxyphenyl)-2-[(3S)-6-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 -1.66 -12.59 1 6 0 73 331.397 4 ↓

Analogs

12236595
12236595

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Popular Name: 2-[(3R)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]-N-[4-(trifluoromethoxy)phenyl]aceta 2-[(3R)-6-methyl-5-oxo-2,3-dihyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 -0.11 -11.5 1 6 0 73 385.367 5 ↓

Analogs

12236594
12236594

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Popular Name: 2-[(3S)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]-N-[4-(trifluoromethoxy)phenyl]aceta 2-[(3S)-6-methyl-5-oxo-2,3-dihyd…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 -0.15 -10.79 1 6 0 73 385.367 5 ↓

Analogs

12236602
12236602

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Popular Name: N-(3,4-difluorophenyl)-2-[(3R)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-difluorophenyl)-2-[(3R)-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.05 -0.18 -13.63 1 5 0 64 337.351 3 ↓

Analogs

12236601
12236601

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Popular Name: N-(3,4-difluorophenyl)-2-[(3S)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-difluorophenyl)-2-[(3S)-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.05 -0.2 -13.47 1 5 0 64 337.351 3 ↓

Analogs

12236607
12236607

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Popular Name: N-(3-chloro-4-fluoro-phenyl)-2-[(3R)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetami N-(3-chloro-4-fluoro-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 -1.07 -12.49 1 5 0 64 353.806 3 ↓

Analogs

12236604
12236604

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Popular Name: N-(3-chloro-4-fluoro-phenyl)-2-[(3S)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetami N-(3-chloro-4-fluoro-phenyl)-2-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 -1.08 -10.73 1 5 0 64 353.806 3 ↓

Analogs

12236610
12236610

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Popular Name: N-(3,4-dimethylphenyl)-2-[(3R)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-dimethylphenyl)-2-[(3R)-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 -1.04 -10.39 1 5 0 64 329.425 3 ↓

Analogs

12236608
12236608

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Popular Name: N-(3,4-dimethylphenyl)-2-[(3S)-6-methyl-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidin-3-yl]acetamide N-(3,4-dimethylphenyl)-2-[(3S)-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 -1.12 -11.24 1 5 0 64 329.425 3 ↓

Parameters Provided:

ring.id = 98781
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 98781 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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