| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| August 6th, 2004 | 31 | Yes |
Popular Name: N1-[4-(trifluoromethoxy)phenyl]-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide N1-[4-(trifluoromethoxy)phenyl]-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.88 | 8.42 | -13.97 | 1 | 7 | 0 | 71 | 449.458 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FAAH1-1-E | Anandamide Amidohydrolase (cluster #1 Of 7), Eukaryotic | Eukaryotes | 8330 | 0.23 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FAAH1_HUMAN | O00519 | Anandamide Amidohydrolase, Human | 5000 | 0.24 | Binding ≤ 10μM |
| FAAH1_RAT | P97612 | Anandamide Amidohydrolase, Rat | 8330 | 0.23 | Binding ≤ 10μM |
