UCSF

ZINC01028145

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Substance Information

In ZINC since Heavy atoms Benign functionality
August 6th, 2004 26 Yes

Popular Name: JNJ 1661010 JNJ 1661010

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CAS Number: 681136-29-8

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.91 9.81 -14.4 1 6 0 61 365.462 3 ↓

Vendor Notes

Note Type Comments Provided By
Target FAAH Selleck Chemicals

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
FAAH1-1-E Anandamide Amidohydrolase (cluster #1 Of 7), Eukaryotic Eukaryotes 34 0.40 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
FAAH1_RAT P97612 Anandamide Amidohydrolase, Rat 10 0.43 Binding ≤ 1μM
FAAH1_HUMAN O00519 Anandamide Amidohydrolase, Human 12 0.43 Binding ≤ 1μM
FAAH1_RAT P97612 Anandamide Amidohydrolase, Rat 10 0.43 Binding ≤ 10μM
FAAH1_HUMAN O00519 Anandamide Amidohydrolase, Human 12 0.43 Binding ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )