| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| August 8th, 2004 | 28 | Yes |
Popular Name: N-[4-(4-benzoylpiperazino)-3-chloro-phenyl]-2,2-dimethyl-propionamide N-[4-(4-benzoylpiperazino)-3-chl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.98 | -1.24 | -13.88 | 1 | 5 | 0 | 52 | 399.922 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY1R-1-E | Neuropeptide Y Receptor Type 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6310 | 0.26 | Functional ≤ 10μM |
| NPY2R-1-E | Neuropeptide Y Receptor Type 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 501 | 0.32 | Functional ≤ 10μM |
| NPY5R-1-E | Neuropeptide Y Receptor Type 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5012 | 0.26 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NPY1R_HUMAN | P25929 | Neuropeptide Y Receptor Type 1, Human | 6309.57344 | 0.26 | Functional ≤ 10μM |
| NPY2R_HUMAN | P49146 | Neuropeptide Y Receptor Type 2, Human | 501.187234 | 0.31 | Functional ≤ 10μM |
| NPY5R_HUMAN | Q15761 | Neuropeptide Y Receptor Type 5, Human | 5011.87234 | 0.26 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
