| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 2nd, 2008 | 16 | No |
Popular Name: DNC008917 DNC008917
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.68 | 6.18 | -5.65 | 1 | 3 | 0 | 41 | 234.324 | 2 | ↓ |
| Mid Mid (pH 6-8) | 2.68 | 6.25 | -36.71 | 0 | 3 | -1 | 44 | 233.316 | 3 | ↓ |
| Lo Low (pH 4.5-6) | 2.68 | 6.58 | -10.5 | 1 | 3 | 0 | 41 | 234.324 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DHI1-3-E | 11-beta-hydroxysteroid Dehydrogenase 1 (cluster #3 Of 3), Eukaryotic | Eukaryotes | 189 | 0.59 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DHI1_HUMAN | P28845 | 11-beta-hydroxysteroid Dehydrogenase 1, Human | 189 | 0.59 | Binding ≤ 1μM |
| DHI1_HUMAN | P28845 | 11-beta-hydroxysteroid Dehydrogenase 1, Human | 189 | 0.59 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glucocorticoid biosynthesis |
