| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 10th, 2008 | 20 | Yes |
Popular Name: Diphenyl-piperidin-4-yl-methanol Diphenyl-piperidin-4-yl-methanol
Find On: PubMed — Wikipedia — Google
CAS Numbers: 115-46-8 , 1798-50-1 , [115-46-8] , [1798-50-1]
"¦Á,¦Á-Diphenyl-4-piperidinomethanol, 98%"
115-46-8; Azacyclonol; Prestwick_84
4-Piperidinemethanol, alpha,alpha-diphenyl-
4-[hydroxy(diphenyl)methyl]piperidine
?,?-Diphenyl-4-piperidinemethanol
ALPHA,ALPHA-DIPHENYL-4-PIPERIDINEMETHANOL
alpha,alpha-Diphenyl-4-piperidinomethanol
alpha,alpha-Diphenyl-4-piperidinomethanol HCl;Azacyclonol HCl
alpha,alpha-Diphenyl-4-piperidinomethanol hydrochloride, 98%
alpha,alpha-Diphenyl-4-piperidinomethanol, 98+%
Diphenyl(4-piperidinyl)methanol hydrochloride
Diphenyl(4-piperidinyl)methanol, 95%
diphenyl(piperidin-4-yl)methanol
Diphenyl(piperidin-4-yl)methanol hydrochloride
Diphenyl-piperidin-4-yl-methanol hydrochloride
Diphenyl-piperidin-4-yl-methanolhydrochloride
Diphenylpiperidin-4-ylmethanol hydrochloride
DIPHENYLPIPERIDINYLMETHANOLHYDROCHLORID
INN); Azacyclonol Hydrochloride (MI
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.51 | 6.89 | -44.33 | 3 | 2 | 1 | 37 | 268.38 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Molecular_Solubility | 4.455 | Bitter DB |
| Mp [°C] | 160 - 163 | Acros Organics |
| Melting_Point | 160-163? | Alfa-Aesar |
| MP | 160-163° | Oakwood Chemical |
| MP | 163 | TCI |
| Mp [°C] | 270 - 281 | Acros Organics |
| MP | 283-285° | Matrix Scientific |
| Target | 5-HT Receptor | Selleck Chemicals |
| Purity | 95% | Fluorochem |
| mechanism | Antagonist to mescaline and LSD | IBScreen Bioactives |
| H phrase | H319: Causes serious eye irritation | Acros Organics |
| H phrase | H319: Causes serious eye irritation; H302: Harmful if swallowed | Acros Organics |
| H phrase | H335: May cause respiratory irritation | Acros Organics |
| H phrase | H335: May cause respiratory irritation; H315: Causes skin irritation; H319: Causes serious eye irritation | Acros Organics |
| Warnings | IRRITANT | Matrix Scientific |
| Target | Others | Selleck Chemicals |
| P phrase | P261: Avoid breathing dust/fume/gas/mist/vapors/spray | Acros Organics |
| P phrase | P261: Avoid breathing dust/fume/gas/mist/vapors/spray; P302+ P352: IF ON SKIN: Wash with plenty of soap and water; P280: Wear protective gloves/protective clothing/eye protection/face protection; P305 + P351 + P338: IF IN EYES: Rinse cautiously with water | Acros Organics |
| P phrase | P280: Wear protective gloves/protective clothing/eye protection/face protection; P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing | Acros Organics |
| biological_use | Psychosedative | IBScreen Bioactives |
| R phrase | R22: Harmful if swallowed.; R36: Irritating to eyes. | Acros Organics |
| R phrase | R36/37/38: Irritating to eyes, respiratory system and skin. | Acros Organics |
| S phrase | S24/25: Avoid contact with skin and eyes. | Acros Organics |
| biological_use | Tranquilliser | IBScreen Bioactives IBScreen Bioactives |
| Hazard | XI: Irritant | Acros Organics |
| Hazard | XN: Harmful | Acros Organics |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH1-2-E | Histamine H1 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 659 | 0.43 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH1_HUMAN | P35367 | Histamine H1 Receptor, Human | 659 | 0.43 | Binding ≤ 1μM |
| HRH1_HUMAN | P35367 | Histamine H1 Receptor, Human | 659 | 0.43 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Histamine receptors |
