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Quick Search ZINC ID or SMILES

Synonyms (37)
Vendors (17)
Annotations (22)
Representations (0)
Notes (6)
Targets (6)
Clustered (3)
Reactome (3)
Rings (0)
Analogs (0)

ZINC12405087

12405087

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since	Heavy atoms	Benign functionality
May 13^th, 2008	29	No

Popular Name: Uridine-5'-triphosphoric acid trisodium salt Uridine-5'-triphosphoric acid tr…

Find On: PubMed — Wikipedia — Google

CAS Numbers: 108321-53-5 , 116295-90-0 , 19817-92-6 , 285978-18-9 , 63-39-8 , [19817-92-6] , [285978-18-9]

Other Names:

({[(2R,3S,4R,5R)-5-(2,4-dioxo-3H-pyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid

5'-UTP; BRN 0071520; C9H15N2O15P3; EINECS 200-558-7; INS316; INS365 Ophthalmic Solution; LS-160841; UTP; Uridine 5'-(tetrahydrogen triphosphate); Uridine 5'-triphosphate; Uridine 5'-triphosphoric acid; Uridine triphosphate; Uridine, 5'-(tetrahydrogen trip

5'-UTP; BRN 0071520; URIDINE 5'-TRIPHOSPHATE; UTP; Uridine 5'-(tetrahydrogen triphosphate); Uridine 5'-triphosphoric acid; Uridine triphosphate; Uteplex; bmse000295

5'-UTP; H4utp; uridine 5'-triphosphoric acid

5'-UTP; Uridine 5'-triphosphate; Uridine mono(tetrahydrogen triphosphate); Uridine triphosphate; Uridine triphosphic acid; Uteplex; UTP

5'-UTP; UTP; Uridine 5'-triphosphate; Uridine mono(tetrahydrogen triphosphate); Uridine triphosphate; Uteplex

5'-UTP;Uridine 5'-triphosphate;Uridine mono(tetrahydrogen triphosphate);Uridine triphosphate;Uteplex;UTP

5'-UTP;UTP;Uridine 5'-triphosphate;Uridine mono(tetrahydrogen triphosphate);Uridine triphosphate;Uteplex

63-39-8; C00075; UTP; Uridine 5'-triphosphate; Uridine triphosphate

63-39-8; UTP; uridine-5'-triphosphate; uridine-triphosphate

CHEBI:13510; CHEBI:9850; CHEBI:27233

Thiophene sulfonamide

Uridine 5'-triphosphate

Uridine 5'-triphosphate tris salt

Uridine 5'-Triphosphate Trisodium Salt Hydrate

Uridine 5'-triphosphate, trisodium salt, hydrate, 90%

Uridine triphosphate

uridine triphosphate trisodium

URIDINE-13C9, 15N2-5 TRIPHOSPHATE SODI U

URIDINE-13C9,15N2-5TRIPHOSPHATESODIU

Uridine-5'-triphosphate disodium salt

Uridine-5'-triphosphate trisodium salt

Uridine-5'-triphosphate trisodium salt dihydrate

Uridine5'-(tetrahydrogen triphosphate)

UTP (3-); UTP trianion

SMILES:

Annotations

Vendors

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL

Vendor Notes

Note Type	Comments	Provided By
Mp [°C]	>140	Acros Organics
UniProt Database Links	ACKA_SALTY; ACKA_THEMA; ACTH_THEAC; ACTH_THEVO; AGLF_HALVD; ARC_RHOER; CBACL_PSEUC; CDA_MYROD; CELA_GLUXY; COFE_METJA; DER_THEMA; DGK_BACSU; ENPP1_HUMAN; ENPP1_MOUSE; ENPP1_RAT; ENTP2_HUMAN; ENTP4_HUMAN; ENTP7_HUMAN; ENTP7_MOUSE; ENTP7_PONAB; ENTP7_XENTR	ChEBI
Therapy	psychostimulant	SMDC MicroSource
Reactome Database Links	REACT_1082; REACT_1094; REACT_1138; REACT_1160; REACT_1179; REACT_1374; REACT_1467; REACT_15538; REACT_1611; REACT_1638; REACT_1645; REACT_18287; REACT_18310; REACT_2030; REACT_2053; REACT_209; REACT_21273; REACT_21292; REACT_21305; REACT_21362; REACT_214	ChEBI
S phrase	S24/25: Avoid contact with skin and eyes.	Acros Organics
Patent Database Links	US2007219224; WO2007089703	ChEBI

Activity (Go SEA)

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
P2RY2-1-E	Purinergic Receptor P2Y2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	130	0.33	Functional ≤ 10μM
P2RY4-1-E	Pyrimidinergic Receptor P2Y4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	90	0.34	Functional ≤ 10μM
P2RY6-1-E	Pyrimidinergic Receptor P2Y6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	6000	0.25	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
P2RY2_MOUSE	P35383	P2Y Purinoceptor 2, Mouse	1260	0.28	Functional ≤ 10μM
P2RY2_RAT	P41232	Purinergic Receptor P2Y2, Rat	130	0.33	Functional ≤ 10μM
P2RY2_HUMAN	P41231	Purinergic Receptor P2Y2, Human	100	0.34	Functional ≤ 10μM
P2RY4_HUMAN	P51582	Pyrimidinergic Receptor P2Y4, Human	100	0.34	Functional ≤ 10μM
P2RY4_RAT	O35811	Pyrimidinergic Receptor P2Y4, Rat	2600	0.27	Functional ≤ 10μM
P2RY6_HUMAN	Q15077	Pyrimidinergic Receptor P2Y6, Human	424	0.31	Functional ≤ 10μM

Direct Reactome Annotations (via ChEBI)

Description	Species
DNA replication initiation	Mus musculus Schizosaccharomyces pombe Sus scrofa Caenorhabditis elegans Oryza sativa Drosophila melanogaster Arabidopsis thaliana Dictyostelium discoideum Plasmodium falciparum Rattus norvegicus Saccharomyces cerevisiae Bos taurus Xenopus tropicalis Danio rerio
Formation of the active cofactor, UDP-glucuronate	Schizosaccharomyces pombe Xenopus tropicalis Oryza sativa Dictyostelium discoideum Saccharomyces cerevisiae Danio rerio Drosophila melanogaster Arabidopsis thaliana Rattus norvegicus Bos taurus Sus scrofa Gallus gallus Taeniopygia guttata Caenorhabditis elegans Canis familiaris Mus musculus Homo sapiens
Formation of the Early Elongation Complex	Dictyostelium discoideum Mus musculus Taeniopygia guttata Canis familiaris Drosophila melanogaster Rattus norvegicus Sus scrofa Danio rerio Bos taurus Xenopus tropicalis Gallus gallus
G alpha (i) signalling events	Sus scrofa Gallus gallus Rattus norvegicus Xenopus tropicalis Danio rerio Mus musculus Bos taurus Homo sapiens Taeniopygia guttata Canis familiaris
Glycogen synthesis	Caenorhabditis elegans Danio rerio Bos taurus Homo sapiens Arabidopsis thaliana Oryza sativa Schizosaccharomyces pombe Canis familiaris Drosophila melanogaster Mus musculus Saccharomyces cerevisiae Taeniopygia guttata Dictyostelium discoideum Gallus gallus Rattus norvegicus Sus scrofa Xenopus tropicalis
P2Y receptors	Rattus norvegicus Gallus gallus Homo sapiens Canis familiaris Sus scrofa Danio rerio Mus musculus Bos taurus Taeniopygia guttata Xenopus tropicalis
RNA Polymerase I Chain Elongation	Taeniopygia guttata Canis familiaris Mus musculus Bos taurus Xenopus tropicalis Danio rerio Rattus norvegicus Gallus gallus Sus scrofa
RNA Polymerase II Pre-transcription Events	Gallus gallus Canis familiaris Bos taurus Dictyostelium discoideum Sus scrofa Rattus norvegicus Taeniopygia guttata Danio rerio Mus musculus Drosophila melanogaster Caenorhabditis elegans Xenopus tropicalis
RNA Polymerase II Promoter Escape	Rattus norvegicus Gallus gallus Caenorhabditis elegans Oryza sativa Xenopus tropicalis Canis familiaris Arabidopsis thaliana Sus scrofa Dictyostelium discoideum Drosophila melanogaster Mus musculus Saccharomyces cerevisiae Danio rerio Taeniopygia guttata Schizosaccharomyces pombe Bos taurus
RNA Polymerase II Transcription Elongation	Caenorhabditis elegans Taeniopygia guttata Dictyostelium discoideum Rattus norvegicus Canis familiaris Bos taurus Drosophila melanogaster Gallus gallus Sus scrofa Danio rerio Mus musculus Xenopus tropicalis
RNA Polymerase II Transcription Initiation	Danio rerio Mus musculus Xenopus tropicalis Gallus gallus Caenorhabditis elegans Dictyostelium discoideum Taeniopygia guttata Saccharomyces cerevisiae Drosophila melanogaster Schizosaccharomyces pombe Oryza sativa Canis familiaris Rattus norvegicus Arabidopsis thaliana Bos taurus Sus scrofa
RNA Polymerase III Abortive And Retractive Initiation	Drosophila melanogaster Arabidopsis thaliana Dictyostelium discoideum Canis familiaris Danio rerio Bos taurus Schizosaccharomyces pombe Taeniopygia guttata Sus scrofa Caenorhabditis elegans Mus musculus Gallus gallus Xenopus tropicalis Rattus norvegicus Oryza sativa
RNA Polymerase III Chain Elongation	Mus musculus Oryza sativa Arabidopsis thaliana Rattus norvegicus Canis familiaris Schizosaccharomyces pombe Danio rerio Gallus gallus Caenorhabditis elegans Xenopus tropicalis Taeniopygia guttata Sus scrofa Drosophila melanogaster Bos taurus Dictyostelium discoideum
Synthesis and interconversion of nucleotide di- and triphosphates	Bos taurus Plasmodium falciparum Drosophila melanogaster Arabidopsis thaliana Taeniopygia guttata Saccharomyces cerevisiae Xenopus tropicalis Caenorhabditis elegans Homo sapiens Canis familiaris Mus musculus Danio rerio Sus scrofa Gallus gallus Schizosaccharomyces pombe Rattus norvegicus Dictyostelium discoideum Oryza sativa
Synthesis of UDP-N-acetyl-glucosamine	Schizosaccharomyces pombe Xenopus tropicalis Drosophila melanogaster Mus musculus Sus scrofa Caenorhabditis elegans Rattus norvegicus Homo sapiens Dictyostelium discoideum Gallus gallus Danio rerio Bos taurus Plasmodium falciparum Canis familiaris Arabidopsis thaliana Saccharomyces cerevisiae Oryza sativa Taeniopygia guttata
Telomere C-strand synthesis initiation	Bos taurus Arabidopsis thaliana Drosophila melanogaster Oryza sativa Sus scrofa Danio rerio Mus musculus Plasmodium falciparum Caenorhabditis elegans Xenopus tropicalis Saccharomyces cerevisiae Schizosaccharomyces pombe Rattus norvegicus Dictyostelium discoideum

Reactome Annotations from Targets (via Uniprot)

Description	Species
G alpha (i) signalling events	Homo sapiens (P2RY4_HUMAN) Rattus norvegicus (P2RY4_RAT)
G alpha (q) signalling events	Mus musculus (P2RY2_MOUSE) Homo sapiens (P2RY2_HUMAN)
P2Y receptors	Homo sapiens (P2RY2_HUMAN) Rattus norvegicus (P2RY4_RAT) Mus musculus (P2RY2_MOUSE)

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.

Synonyms (37)
Vendors (17)
Annotations (22)
Representations (0)
Notes (6)
Targets (6)
Clustered (3)
Reactome (3)
Rings (0)
Analogs (0)