UCSF

ZINC12495069

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Substance Information

In ZINC since Heavy atoms Benign functionality
May 16th, 2008 29 No

Popular Name: DTTP DTTP

Find On: PubMed — Wikipedia — Google

CAS Numbers: 18423-43-3 , 27821-54-1 , 3624-46-2 , 365-08-2 , [18423-43-3]

Other Names:

2'-Deoxy-thymidine-5'-triphosphate tetrasodium salt

2'-Deoxythymidine 5'-triphosphate; 2'-Deoxythymidine triphosphate; 5'-TTP; 5-Methyl-dUTP; Deoxy-TTP; Deoxythymidine 5'-triphosphate; Deoxythymidine triphosphate; dTTP; Thymidine 5'-triphosphate; Thymidine 5'-triphosphic acid; Thymidine mono(tetrahydrogen

2'-Deoxythymidine 5'-triphosphate; 2'-Deoxythymidine triphosphate; 5'-TTP; 5-Methyl-dUTP; Deoxy-TTP; Deoxythymidine 5'-triphosphate; Deoxythymidine triphosphate; TTP; Thymidine 5'-triphosphate; Thymidine mono(tetrahydrogen triphosphate); Thymidine triphos

2'-Deoxythymidine 5'-triphosphate; 2'-Deoxythymidine triphosphate; 5-Methyl-dUTP; 5'-TTP; Deoxy-TTP; Deoxythymidine 5'-triphosphate; Deoxythymidine triphosphate; dThd5'PPP; dTTP; pppdT; Thymidine 5'-triphosphate; Thymidine 5'-triphosphic acid; Thymidine m

2'-Deoxythymidine 5'-triphosphate;2'-Deoxythymidine triphosphate;5'-TTP;5-Methyl-dUTP;Deoxy-TTP;Deoxythymidine 5'-triphosphate;Deoxythymidine triphosphate;dTTP;Thymidine 5'-triphosphate;Thymidine mono(tetrahydrogen triphosphate);Thymidine triphosphate;TTP

2'-Deoxythymidine 5'-triphosphate;2'-Deoxythymidine triphosphate;5'-TTP;5-Methyl-dUTP;Deoxy-TTP;Deoxythymidine 5'-triphosphate;Deoxythymidine triphosphate;TTP;Thymidine 5'-triphosphate;Thymidine mono(tetrahydrogen triphosphate);Thymidine triphosphate;dTTP

2'-deoxythymidine triphosphate

2'-Deoxythymidine triphosphate; 5'-TTP; Deoxy-TTP; Deoxythymidine 5'-triphosphate; Deoxythymidine triphosphate; EINECS 206-669-7; LS-153785; TTP; TTP (nucleotide); Thymidine 5'-(tetrahydrogen triphosphate); Thymidine 5'-triphosphate; dTTP

2'-deoxythymidine triphosphate; 5'-TTP; dThd5'PPP; deoxy-TTP; pppdT; thymidine 5'-triphosphate

2'-Deoxythymidine-5'-triphosphate trisodium salt

365-08-2; TTP; dTTP; thymidine 5'-triphosphate; thymidine triphosphate

C00459; Deoxythymidine 5'-triphosphate; Deoxythymidine triphosphate; TTP; dTTP

CHEBI:46175; CHEBI:14093; CHEBI:10530; CHEBI:27000

DNC000052

dTTP trianion; dTTP(3-)

dTTP(3-)

dTTP(4-)

MFCD00043010

MFCD00080338

Sodium (2R,3S,5R)-2-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-olate

Thymidine 5'-triphosphate

THYMIDINE 5'-TRIPHOSPHATE SODIUM SALT

Thymidine 5'-triphosphate tetrasodium salt

[hydroxy({hydroxy[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3H-pyrimidin-1-yl)oxolan-2-yl]methoxyphosphoryl}oxy)phosphoryl]oxyphosphonic acid

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL

Vendor Notes

Note Type Comments Provided By
UniProt Database Links COFE_METJA; DCD_METJA; DCTD_BPT2; DCTD_BPT4; DCTD_HUMAN; DCTD_MOUSE; DCTD_PONAB; DCTD_RAT; DCTD_YEAST; DCTP1_BOVIN; DCTP1_HUMAN; DCTP1_MOUSE; DCTP1_RAT; DPOZ_YEAST; DRTS_TRYBB; ENPP1_HUMAN; ENPP1_MOUSE; ENPP1_RAT; ENTP4_HUMAN; GLMU_METJA; HDDC_ANETH; IDE_ ChEBI
UniProt Database Links DCD_METJA; DCTD_BPT2; DCTD_BPT4; DCTD_HUMAN; DCTD_MOUSE; DCTD_PONAB; DCTD_RAT; DCTD_YEAST; DCTP1_BOVIN; DCTP1_HUMAN; DCTP1_MOUSE; DCTP1_RAT; DPOZ_YEAST; DRTS_TRYBB; GLMU_METJA; HDDC_ANETH; KITH_ECO57; KITH_ECOL6; KITH_ECOLI; KITH_SHIFL; KTHY_ABVP; KTHY_AC ChEBI
Patent Database Links EP1806400; US2007224611 ChEBI
Reactome Database Links REACT_21273; REACT_21292; REACT_21362; REACT_21416; REACT_7985; REACT_8004; REACT_8019; REACT_8029; REACT_9039; REACT_91 ChEBI

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Assembly of telomerase and telomere extension
DNA replication initiation
Minus-strand DNA synthesis
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Processive synthesis on the C-strand of the telomere
Synthesis and interconversion of nucleotide di- and triphosphates
Telomere C-strand synthesis initiation
Telomere Extension By Telomerase

Analogs ( Draw Identity 99% 90% 80% 70% )