In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
May 16th, 2008 | 15 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | -4.08 | 1.5 | -88.89 | 5 | 6 | 0 | 125 | 218.253 | 8 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
UniProt Database Links | CEL_HUMAN; CHBF_ECOLI; CHBG_ECOLI; IFA1_CAEEL; IFA2_CAEEL; IFA3_CAEEL; IFA4_CAEEL; IFB1_CAEEL; IFB2_CAEEL; IFC1_CAEEL; IFC2_CAEEL; IFD1_CAEEL; IFD2_CAEEL; IFP1_CAEEL; LEG10_HUMAN; LEG10_MOUSE; LEG10_PONPY; PPK4_CELBM; PTEA_GEOSE; PTEB_AERHY; PTEB_GEOSE; P | ChEBI |
Reactome Database Links | REACT_163645; REACT_163850; REACT_163962; REACT_25020; REACT_25269; REACT_25382 | ChEBI |
Description | Species |
---|---|
Advanced glycosylation endproduct receptor signaling |
|
DEx/H-box helicases activate type I IFN and inflammatory cytokines production | |
RIP-mediated NFkB activation via ZBP1 | |
Scavenging by Class A Receptors | |
Scavenging by Class H Receptors | |
TAK1 activates NFkB by phosphorylation and activation of IKKs complex | |
TRAF6 mediated NF-kB activation |