| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 18th, 2008 | 18 | No |
Popular Name: (5Z)-5-[[4-(trifluoromethyl)phenyl]methylene]thiazolidine-2,4-dione (5Z)-5-[[4-(trifluoromethyl)phen…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.38 | 4 | -7.93 | 1 | 3 | 0 | 50 | 273.235 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PIM1-1-E | Serine/threonine-protein Kinase PIM1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 330 | 0.50 | Binding ≤ 10μM |
| PIM2-1-E | Serine/threonine-protein Kinase PIM2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 80 | 0.55 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PIM1_HUMAN | P11309 | Serine/threonine-protein Kinase PIM1, Human | 330 | 0.50 | Binding ≤ 1μM |
| PIM2_HUMAN | Q9P1W9 | Serine/threonine-protein Kinase PIM2, Human | 80 | 0.55 | Binding ≤ 1μM |
| PIM1_HUMAN | P11309 | Serine/threonine-protein Kinase PIM1, Human | 330 | 0.50 | Binding ≤ 10μM |
| PIM2_HUMAN | Q9P1W9 | Serine/threonine-protein Kinase PIM2, Human | 80 | 0.55 | Binding ≤ 10μM |
