| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 20th, 2008 | 28 | No |
Popular Name: Megestrol Acetate Megestrol Acetate
Find On: PubMed — Wikipedia — Google
CAS Number: 595-33-5
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.09 | 11.95 | -14.64 | 0 | 4 | 0 | 60 | 384.516 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | . | ZereneX Building Blocks |
| MP | 218 | TCI |
| biological_use | against carcinoma of the breast and endometrium | IBScreen Bioactives |
| mechanism | Also has direct cytotoxic effects on breast cancer cells in tissue culture and suppresses luteinising hormone release from the pituitary | IBScreen Bioactives |
| biological_use | Antineoplastic agent | IBScreen Bioactives |
| biological_use | Oral contraceptive | IBScreen Bioactives ZereneX Building Blocks |
| mechanism | The biochemical mechanism of progestin antitumour activity is not well but may involve interaction with progesterone and glucocorticoid receptors, androgenic properties | IBScreen Bioactives |
| mechanism | The precise mechanism by which megestrol acetate produces effects in anorexia and cachexia is unknown at the present time | IBScreen Bioactives IBScreen Bioactives |
No pre-computed analogs available. Try a structural similarity search.