| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 19th, 2008 | 32 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.28 | 3.95 | -71.72 | 3 | 11 | -1 | 165 | 451.5 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRAB-1-E | Granzyme B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 122 | 0.30 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRAB_HUMAN | P10144 | Granzyme B, Human | 122 | 0.30 | Binding ≤ 1μM |
| GRAB_HUMAN | P10144 | Granzyme B, Human | 122 | 0.30 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation, myristolyation of BID and translocation to mitochondria | |
| NOTCH2 intracellular domain regulates transcription |
