In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 19th, 2008 | 24 | No |
Popular Name: 3-(3-chlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione 3-(3-chlorophenyl)-4-(1-methylin…
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.04 | 8.76 | -12.25 | 1 | 4 | 0 | 55 | 336.778 | 2 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
KPCG-1-E | Protein Kinase C Gamma (cluster #1 Of 4), Eukaryotic | Eukaryotes | 2000 | 0.33 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
KPCG_RAT | P63319 | Protein Kinase C Gamma, Rat | 2000 | 0.33 | Binding ≤ 10μM |
Description | Species |
---|---|
Calmodulin induced events | |
Disinhibition of SNARE formation | |
G alpha (z) signalling events | |
Response to elevated platelet cytosolic Ca2+ | |
Trafficking of GluR2-containing AMPA receptors | |
WNT5A-dependent internalization of FZD4 |