In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 20th, 2008 | 25 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.57 | 10.59 | -51.36 | 1 | 4 | -1 | 69 | 330.363 | 4 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
TERT-2-E | Telomerase Reverse Transcriptase (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5000 | 0.30 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
TERT_HUMAN | O14746 | Telomerase Reverse Transcriptase, Human | 5000 | 0.30 | Binding ≤ 10μM |
Description | Species |
---|---|
formation of the beta-catenin:TCF transactivating complex | |
Telomere Extension By Telomerase |