| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 20th, 2008 | 19 | Yes |
Popular Name: 3-(3-amino-3-oxo-propyl)-4,6-dichloro-1H-indole-2-carboxylic 3-(3-amino-3-oxo-propyl)-4,6-dic…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.59 | 2.99 | -47.48 | 3 | 5 | -1 | 99 | 300.121 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| F16P1-1-E | Fructose-1,6-bisphosphatase 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2200 | 0.42 | Binding ≤ 10μM |
| F16P2-1-E | Fructose-1,6-bisphosphatase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2200 | 0.42 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| F16P1_HUMAN | P09467 | Fructose-1,6-bisphosphatase, Human | 2200 | 0.42 | Binding ≤ 10μM |
| F16P2_HUMAN | O00757 | Fructose-1,6-bisphosphatase 2, Human | 2200 | 0.42 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Gluconeogenesis |
