| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 20th, 2008 | 20 | Yes |
Popular Name: 4,6-dichloro-3-(4-hydroxy-4-oxo-butyl)-1H-indole-2-carboxylic 4,6-dichloro-3-(4-hydroxy-4-oxo-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.37 | 6.73 | -107.85 | 1 | 5 | -2 | 96 | 314.124 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| F16P1-1-E | Fructose-1,6-bisphosphatase 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.42 | Binding ≤ 10μM |
| F16P2-1-E | Fructose-1,6-bisphosphatase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.42 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| F16P1_HUMAN | P09467 | Fructose-1,6-bisphosphatase, Human | 1000 | 0.42 | Binding ≤ 1μM |
| F16P2_HUMAN | O00757 | Fructose-1,6-bisphosphatase 2, Human | 1000 | 0.42 | Binding ≤ 1μM |
| F16P1_HUMAN | P09467 | Fructose-1,6-bisphosphatase, Human | 1000 | 0.42 | Binding ≤ 10μM |
| F16P2_HUMAN | O00757 | Fructose-1,6-bisphosphatase 2, Human | 1000 | 0.42 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Gluconeogenesis |
