| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 27 | No |
Popular Name: DNC014844 DNC014844
Find On: PubMed — Wikipedia — Google
CAS Numbers: 132619-66-0 , 93939-77-6
2',3'-Dideoxycytidine 5'-triphosphate
2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE LITHIUM SALT
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.74 | -0.65 | -360.84 | 2 | 15 | -4 | 241 | 447.126 | 8 | ↓ |
| Mid Mid (pH 6-8) | -3.74 | -1.81 | -224.75 | 3 | 15 | -3 | 238 | 448.134 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOLB-1-E | DNA Polymerase Beta (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1300 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOLB_HUMAN | P06746 | DNA Polymerase Beta, Human | 1300 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Base-free sugar-phosphate removal via the single-nucleotide replacement pathway | |
| Removal of DNA patch containing abasic residue | |
| Resolution of AP sites via the single-nucleotide replacement pathway |
