| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 20 | Yes |
Popular Name: 4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylaniline 4-(6-Methoxybenzo[d]thiazol-2-yl…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 10205-71-7 , [10205-71-7]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.43 | 7.47 | -8.4 | 0 | 3 | 0 | 25 | 284.384 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| A4-2-E | Beta Amyloid A4 Protein (cluster #2 Of 5), Eukaryotic | Eukaryotes | 2 | 0.61 | Binding ≤ 10μM |
| LUCI-1-E | Luciferin 4-monooxygenase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2700 | 0.39 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| A4_HUMAN | P05067 | Beta Amyloid A4 Protein, Human | 1.9 | 0.61 | Binding ≤ 1μM |
| LUCI_PHOPY | P08659 | Luciferin 4-monooxygenase, Phopy | 700 | 0.43 | Binding ≤ 1μM |
| A4_HUMAN | P05067 | Beta Amyloid A4 Protein, Human | 1.9 | 0.61 | Binding ≤ 10μM |
| LUCI_PHOPE | Q27757 | Luciferin 4-monooxygenase, Phope | 2700 | 0.39 | Binding ≤ 10μM |
| LUCI_PHOPY | P08659 | Luciferin 4-monooxygenase, Phopy | 700 | 0.43 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Advanced glycosylation endproduct receptor signaling | |
| Amyloids | |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | |
| ECM proteoglycans | |
| Formyl peptide receptors bind formyl peptides and many other ligands | |
| G alpha (i) signalling events | |
| G alpha (q) signalling events | |
| Platelet degranulation | |
| RIP-mediated NFkB activation via ZBP1 | |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex | |
| The NLRP3 inflammasome | |
| TRAF6 mediated NF-kB activation |
No pre-computed analogs available. Try a structural similarity search.