| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 25 | Yes |
Popular Name: N-(3-chloro-4-fluoro-phenyl)-6,7-diethoxy-quinazolin-4-amine N-(3-chloro-4-fluoro-phenyl)-6,7…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.80 | 10.4 | -9.25 | 1 | 5 | 0 | 56 | 361.804 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| F16P1-2-E | Fructose-1,6-bisphosphatase 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 530 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| F16P1_HUMAN | P09467 | Fructose-1,6-bisphosphatase, Human | 530 | 0.35 | Binding ≤ 1μM |
| F16P1_PIG | P00636 | Fructose-1,6-bisphosphatase, Pig | 3100 | 0.31 | Binding ≤ 10μM |
| F16P1_HUMAN | P09467 | Fructose-1,6-bisphosphatase, Human | 530 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Gluconeogenesis |
