| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 29 | Yes |
Popular Name: 5-[4-(2,4-dichlorophenyl)phenyl]-2-(4-pyridylmethyl)pyrazole-3-carboxylic 5-[4-(2,4-dichlorophenyl)phenyl]…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.26 | 12.04 | -44.7 | 0 | 5 | -1 | 71 | 423.279 | 5 | ↓ |
| Lo Low (pH 4.5-6) | 5.26 | 12.32 | -50.21 | 1 | 5 | 0 | 72 | 424.287 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SYMC-1-E | Methionyl-tRNA Synthetase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 910 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SYMC_HUMAN | P56192 | Methionyl-tRNA Synthetase, Human | 910 | 0.29 | Binding ≤ 1μM |
| SYMC_HUMAN | P56192 | Methionyl-tRNA Synthetase, Human | 910 | 0.29 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Cytosolic tRNA aminoacylation |
