| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 25 | No |
Popular Name: Lactacystin Lactacystin
Find On: PubMed — Wikipedia — Google
CAS Numbers: 133343-34-7 , [133343-34-7]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -2.76 | -0.63 | -56.94 | 4 | 9 | -1 | 156 | 375.423 | 8 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Purity | >95% | Fluorochem |
| PUBCHEM_PATENT_ID | EP0723957A1; EP0820283A1; EP0863913A1; EP0876483A1; EP0914428A2; EP0937258A2; EP0942742A1; EP0943624A1; EP0956031A1; EP0957934A1; EP0977776A2; EP0995757A2; EP1021407A1; EP1034263A1; EP1053750A1; EP1056834A2; EP1058689A1; EP1062243A2; US5266588; US5756764 | IBM Patent Data |
| UniProt Database Links | PSA_STRCO; PSB_STRCO; SQSTM_MOUSE; SQSTM_RAT | ChEBI |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SF3B3-1-E | Splicing Factor 3B Subunit 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3481 | 0.31 | Binding ≤ 10μM |
| Z100256-1-O | Proteasome (cluster #1 Of 1), Other | Other | 259 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z100256 | Z100256 | Proteasome | 259 | 0.37 | Binding ≤ 1μM |
| Z100256 | Z100256 | Proteasome | 259 | 0.37 | Binding ≤ 10μM |
| SF3B3_HUMAN | Q15393 | Splicing Factor 3B Subunit 3, Human | 3481 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| mRNA Splicing - Major Pathway | |
| mRNA Splicing - Minor Pathway |
