| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 22nd, 2008 | 18 | Yes |
Popular Name: 4-[(1R,3R)-3-(3,5-dichlorophenyl)-2,2-dimethyl-cyclopropyl]-3H-imidazole 4-[(1R,3R)-3-(3,5-dichlorophenyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.70 | 9.96 | -38.44 | 2 | 2 | 1 | 30 | 282.194 | 2 | ↓ |
| Mid Mid (pH 6-8) | 3.70 | 9.7 | -7.51 | 1 | 2 | 0 | 29 | 281.186 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SL9A1-1-E | Sodium/hydrogen Exchanger 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4000 | 0.42 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SL9A1_HUMAN | P19634 | Sodium/hydrogen Exchanger 1, Human | 4000 | 0.42 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Hyaluronan uptake and degradation | |
| Sodium/Proton exchangers |
