| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 22nd, 2008 | 25 | No |
Popular Name: Andrographolide Andrographolide
Find On: PubMed — Wikipedia — Google
CAS Number: 5508-58-7
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.05 | 3.01 | -13.64 | 3 | 5 | 0 | 87 | 350.455 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| mechanism | Activator of alpha-1A-adrenoceptor | IBScreen Bioactives IBScreen Bioactives |
| biological_use | Cardioprotective | IBScreen Bioactives |
| biological_use | Hepatoprotective | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Prevents oxygen radical production by human neutrophils | IBScreen Bioactives |
| biological_use | Shown to be effective against certain cancers and is an effective purgative | IBScreen Bioactives |
| mechanism | Suppressor of the expression of inducible nitric oxide synthase | IBScreen Bioactives |
No pre-computed analogs available. Try a structural similarity search.