Physical Representations
|
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
|
Ref
Reference (pH 7)
|
4.33 |
11.57 |
-13.2 |
1 |
4 |
0 |
56 |
368.558 |
11 |
↓
|
Clustered Target Annotations
| Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
|
KPCD-2-E |
Protein Kinase C Delta (cluster #2 Of 4), Eukaryotic |
Eukaryotes |
1890 |
0.31 |
Binding ≤ 10μM
|
ChEMBL Target Annotations
| Uniprot |
Swissprot |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
|
KPCD_HUMAN |
Q05655
|
Protein Kinase C Delta, Human |
1890 |
0.31 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
| Description |
Species |
|
Apoptotic cleavage of cellular proteins |
|
|
Calmodulin induced events |
|
|
DAG and IP3 signaling |
|
|
Effects of PIP2 hydrolysis |
|
|
G alpha (z) signalling events |
|
|
HuR stabilizes mRNA |
|
|
Interferon gamma signaling |
|
|
Role of phospholipids in phagocytosis |
|
|
VEGFR2 mediated cell proliferation |
|
No pre-computed analogs available. Try a structural similarity search.
