| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 20 | Yes |
Popular Name: (2S)-1-[(2S)-2-aminobutanoyl]-N-ethyl-indoline-2-carboxamide (2S)-1-[(2S)-2-aminobutanoyl]-N-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.56 | 3.35 | -40.69 | 4 | 5 | 1 | 77 | 276.36 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPP2-1-E | Tripeptidyl Aminopeptidase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPP2_RAT | Q64560 | Tripeptidyl Aminopeptidase, Rat | 12 | 0.55 | Binding ≤ 1μM |
| TPP2_RAT | Q64560 | Tripeptidyl Aminopeptidase, Rat | 12 | 0.55 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Antigen processing: Ubiquitination & Proteasome degradation |
